NMU and SNTA1

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		NMU	SNTA1
Gene Name		neuromedin U	syntrophin, alpha 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Terminal Bouton	Intracellular Cytoplasm Cytoskeleton Syntrophin Complex Lateral Plasma Membrane Cell Junction Neuromuscular Junction Sarcolemma Protein Complex Postsynaptic Membrane
	Molecular Function	Receptor Binding Neuromedin U Receptor Binding	Actin Binding Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Ion Channel Binding Nitric-oxide Synthase Binding ATPase Binding
	Biological Process	Gastric Acid Secretion Regulation Of Smooth Muscle Contraction Signal Transduction G-protein Coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Digestion Photoperiodism Sensory Perception Of Pain Eating Behavior Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Hormone Secretion Positive Regulation Of Synaptic Transmission	Regulation Of Heart Rate Regulation Of Vasoconstriction By Circulating Norepinephrine Muscle Contraction Neuromuscular Junction Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: KRTAP5-9 NMUR1 NMUR2 NOTCH2NL SNTA1	72 interactors: ABCA1 ABCC4 ACTA2 ADAMTS6 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B BAI1 BAI2 BAI3 C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA F8A1 FABP1 FAM189B GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TLX3 TRA TRBV12-3 UTRN XRCC6
Entrez ID		10874	6640
HPRD ID		05485	03009
Ensembl ID		ENSG00000109255	ENSG00000101400
Uniprot IDs		P48645	B4DX40 Q13424
PDB IDs
Enriched GO Terms of Interacting Partners?		Inositol Phosphate-mediated Signaling Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Calcium-mediated Signaling Neuropeptide Signaling Pathway Regulation Of Vasoconstriction By Circulating Norepinephrine Chloride Transport Second-messenger-mediated Signaling Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Regulation Of Muscle Contraction Reduction Of Food Intake In Response To Dietary Excess Activation Of Phospholipase A2 Activity Muscle Contraction Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Phospholipase A2 Activity Inorganic Anion Transport Muscle System Process Calcium Ion Transport Regulation Of Phospholipase A2 Activity Arachidonic Acid Secretion Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Response To Dietary Excess Grooming Behavior Ventricular Cardiac Muscle Cell Action Potential Regulation Of Membrane Repolarization Synaptic Transmission Cardiac Muscle Cell Action Potential Involved In Contraction Eating Behavior Anion Transport Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Response To Pain Long-chain Fatty Acid Transport Regulation Of Cardiac Muscle Cell Contraction Activation Of Phospholipase C Activity Neuromuscular Junction Development Regulation Of Smooth Muscle Contraction Metal Ion Transport Positive Regulation Of Phospholipase C Activity Regulation Of Vasoconstriction Acid Secretion Smooth Muscle Contraction Fatty Acid Transport Cell-cell Signaling Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Hydrolase Activity	Cell-cell Signaling Synaptic Transmission Regulation Of Ion Transmembrane Transport Signaling Cell Communication Regulation Of Ion Transport Muscle System Process Muscle Contraction Regulation Of Heart Contraction G-protein Coupled Receptor Signaling Pathway Metal Ion Transport Ion Transport Regulation Of Muscle Contraction Blood Circulation Negative Regulation Of Adrenergic Receptor Signaling Pathway Monovalent Inorganic Cation Transport Regulation Of Sodium Ion Transmembrane Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Cation Transport Regulation Of Striated Muscle Contraction Cell Surface Receptor Signaling Pathway Cation Transmembrane Transport Transmembrane Transport Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Ion Homeostasis Positive Regulation Of Cell Proliferation Ion Transmembrane Transport Potassium Ion Import Regulation Of Phosphorus Metabolic Process Behavior Response To Stimulus Regulation Of Membrane Potential Positive Regulation Of Transport Regulation Of Cellular Process Regulation Of Sodium Ion Transport CGMP Metabolic Process Positive Regulation Of Ion Transport Response To Drug Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Action Potential Regulation Of Body Fluid Levels Multicellular Organismal Response To Stress Response To Stress Cellular Response To Stimulus
Tagcloud ?		alter animals burden carcinogen content dawley estrogen exercise exercised exercising experiment final grams hypothesized incline latency microg multiplicity overshadowed prior progressive pronounced saturated sedentary sets sprague terminated treadmill workload	acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound
Tagcloud (Difference) ?		alter animals burden carcinogen content dawley estrogen exercise exercised exercising experiment final grams hypothesized incline latency microg multiplicity overshadowed prior progressive pronounced saturated sedentary sets sprague terminated treadmill workload	acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound
Tagcloud (Intersection) ?