NMU and SNTA1

Number of citations of the paper that reports this interaction (PubMedID 15123239)
0

Data Source:
BioGRID (unspecified method)

		NMU	SNTA1
Description		neuromedin U	syntrophin alpha 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Terminal Bouton	Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Syntrophin Complex Membrane Lateral Plasma Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Anchoring Junction
	Molecular Function	Signaling Receptor Binding Protein Binding Type 1 Neuromedin U Receptor Binding Type 2 Neuromedin U Receptor Binding Neuromedin U Receptor Binding	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Transmembrane Transporter Binding Nitric-oxide Synthase Binding ATPase Binding
	Biological Process	Temperature Homeostasis Gastric Acid Secretion Positive Regulation Of Systemic Arterial Blood Pressure Regulation Of Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Photoperiodism Positive Regulation Of Heart Rate Positive Regulation Of Heat Generation Eating Behavior Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of Smooth Muscle Contraction Positive Regulation Of Hormone Secretion Positive Regulation Of Synaptic Transmission Regulation Of Feeding Behavior Negative Regulation Of Gastric Acid Secretion Energy Homeostasis Negative Regulation Of Gastric Emptying Positive Regulation Of Stomach Fundus Smooth Muscle Contraction Positive Regulation Of Prolactin Secretion Negative Regulation Of Eating Behavior Positive Regulation Of Sensory Perception Of Pain Negative Regulation Of Feeding Behavior Regulation Of Grooming Behavior	Regulation Of Heart Rate Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases			Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Daytime sleep phenotypes ( 27126917) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432 32277301) Urinary albumin-to-creatinine ratio ( 31511532 31630189) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)	HDL cholesterol x physical activity interaction (1df test) ( 30670697) HDL cholesterol x physical activity interaction (2df test) ( 30670697)
Interacting Genes		16 interacting genes: CYSRT1 DCDC2 KRT34 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-6 KRTAP12-3 KRTAP17-1 KRTAP5-9 NBPF19 NMUR1 NMUR2 NOTCH2NLA SNTA1 TNS2	76 interacting genes: ABCA1 ABCC4 ACTA2 ADAMTS6 ADGRB1 ADGRB2 ADGRB3 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA DTNB ENTREP3 F8A1 FABP1 GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 RPS6KA1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TIAM1 TLX3 TRA TRBV12-3 UTRN VANGL2 XRCC6
Entrez ID		10874	6640
HPRD ID		05485	03009
Ensembl ID		ENSG00000109255	ENSG00000101400
Uniprot IDs		A0A0B4J202 A0A250SH36 E9PDJ7 P48645 Q86WB6	B3KTR0 Q13424
PDB IDs		7W53 7W55 7XK8
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Neuromedin U Receptor Activity Neuromedin U Binding Neuropeptide Receptor Activity Epidermis Development Structural Constituent Of Skin Epidermis Positive Regulation Of Calcium-mediated Signaling	Plasma Membrane System Process Regulation Of System Process Membrane G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Activity Regulation Of Blood Circulation Circulatory System Process Vascular Process In Circulatory System Monoatomic Ion Channel Complex Regulation Of Multicellular Organismal Process Regulation Of Heart Contraction Blood Vessel Diameter Maintenance Regulation Of Tube Size Basolateral Plasma Membrane Monoatomic Ion Transmembrane Transport Regulation Of Biological Quality Transmembrane Transport Muscle Contraction Inorganic Ion Transmembrane Transport Metal Ion Transport Monoatomic Ion Transport Regulation Of Heart Rate Inorganic Cation Transmembrane Transport Regulation Of Membrane Potential Monoatomic Cation Transmembrane Transport Monoatomic Cation Transport Cardiac Muscle Cell Action Potential Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Muscle System Process Synapse Inward Rectifier Potassium Channel Activity Synaptic Signaling Vasodilation Intracellular Signaling Cassette Regulation Of Monoatomic Ion Transmembrane Transport Adrenergic Receptor Activity CGMP-mediated Signaling Calcium-mediated Signaling Action Potential Potassium Ion Transport Regulation Of Blood Pressure Regulation Of Muscle Contraction Regulation Of Monoatomic Ion Transport Voltage-gated Sodium Channel Complex Signal Transduction Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Multicellular Organismal Process
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