TUBGCP2 and PCNT

Number of citations of the paper that reports this interaction (PMID 12221128)
59

Data Source:
HPRD (in vivo)

		TUBGCP2	PCNT
Gene Name		tubulin, gamma complex associated protein 2	pericentrin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleoplasm Centrosome Microtubule Organizing Center Cytosol Cytoplasmic Microtubule Membrane	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Microtubule Membrane Motile Cilium Centriolar Satellite Ciliary Basal Body Intercellular Bridge
	Molecular Function	Protein Binding	Protein Binding Calmodulin Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Complex Assembly Microtubule Nucleation	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Cell Cycle In Utero Embryonic Development Neuron Migration Organelle Organization Spindle Organization Cerebellar Cortex Morphogenesis Olfactory Bulb Development Limb Morphogenesis Multicellular Organism Growth Cilium Assembly Negative Regulation Of Apoptotic Process Brain Morphogenesis Neural Precursor Cell Proliferation Positive Regulation Of Intracellular Protein Transport
Pathways		G2/M Transition Centrosome maturation Mitotic G2-G2/M phases Recruitment of NuMA to mitotic centrosomes Cell Cycle, Mitotic Recruitment of mitotic centrosome proteins and complexes	Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: PCNT UBC	11 interactors: AKAP9 CALM1 CALM2 CCP110 CEP55 DISC1 PCM1 TP53BP1 TUBG1 TUBGCP2 TUBGCP3
Entrez ID		10844	5116
HPRD ID		18245	05804
Ensembl ID			ENSG00000160299
Uniprot IDs		Q53EQ3 Q9BSJ2	O95613
PDB IDs
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Viral Protein Processing Mitotic Cell Cycle Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Notch Receptor Processing Virion Assembly Cell Cycle Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Glycogen Biosynthetic Process Intracellular Transport Of Virus Cellular Polysaccharide Biosynthetic Process Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Olfactory Bulb Development Cerebellar Cortex Morphogenesis Brain Morphogenesis Polysaccharide Biosynthetic Process Olfactory Lobe Development Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of ERBB Signaling Pathway Cerebellum Morphogenesis Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Hindbrain Morphogenesis Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Toll-like Receptor 2 Signaling Pathway Signal Transduction Involved In DNA Damage Checkpoint Toll-like Receptor 9 Signaling Pathway Signal Transduction Involved In Cell Cycle Checkpoint Glycogen Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Mitotic Cell Cycle Microtubule Cytoskeleton Organization Microtubule Nucleation Cell Cycle Process Microtubule Polymerization Microtubule-based Process Cell Cycle Organelle Organization Microtubule Polymerization Or Depolymerization Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Transporter Activity Regulation Of Cytokinesis Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cytoskeleton Organization Regulation Of Heart Rate Positive Regulation Of Ion Transmembrane Transport Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Protein Polymerization Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Heart Contraction Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process
Tagcloud ?			aberration arg585x assumed bones capabilities careful derive discreet disturbance dwarfism firm glu1774x heterozygous integrating intrauterine leu1361arg microcephaly mopd moyamoya proportionate provoke retardation segregate sga somatotropic specification suggestive syndromic underline
Tagcloud (Difference) ?			aberration arg585x assumed bones capabilities careful derive discreet disturbance dwarfism firm glu1774x heterozygous integrating intrauterine leu1361arg microcephaly mopd moyamoya proportionate provoke retardation segregate sga somatotropic specification suggestive syndromic underline
Tagcloud (Intersection) ?