TUBGCP2 and KIF14

Number of citations of the paper that reports this interaction (PubMedID 25348260)
69

Data Source:
BioGRID (unspecified method)

		TUBGCP2	KIF14
Description		tubulin gamma complex component 2	kinesin family member 14
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Gamma-tubulin Complex Nucleoplasm Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Cytoplasmic Microtubule Membrane Ciliary Basal Body	Nucleus Cytoplasm Spindle Cytosol Cytoskeleton Kinesin Complex Microtubule Plasma Membrane Membrane Midbody Spindle Midzone Flemming Body
	Molecular Function	Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity Tubulin Binding ATP Hydrolysis Activity Protein Kinase Binding PDZ Domain Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Neuron Migration Microtubule Nucleation Brain Development Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly	Regulation Of Cell Growth Microtubule-based Movement Microtubule Depolymerization Mitotic Metaphase Chromosome Alignment Positive Regulation Of Cell Population Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Cerebellar Granular Layer Structural Organization Cerebellar Purkinje Cell Layer Structural Organization Cerebellar Cortex Development Hippocampus Development Olfactory Bulb Development Cell Proliferation In Forebrain Cerebral Cortex Development Regulation Of Cell Adhesion Regulation Of Cell Migration SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Myelination Activation Of Protein Kinase Activity Positive Regulation Of Cytokinesis Regulation Of Rap Protein Signal Transduction Negative Regulation Of Integrin Activation Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Establishment Of Protein Localization Cell Division Regulation Of Cell Maturation Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	RHO GTPases activate CIT RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Mild influenza (H1N1) infection ( 26379185) Nonunion in individuals with fractures ( 30680360)	Femur bone mineral density x serum urate levels interaction ( 34046847) Neurofibrillary tangles ( 31497858) Refractive error ( 32231278) Tandem gait ( 26219847)
Interacting Genes		4 interacting genes: CEBPA KIF14 PCNT UBC	3 interacting genes: CLK1 TUBG1 TUBGCP2
Entrez ID		10844	9928
HPRD ID		18245	06605
Ensembl ID		ENSG00000130640	ENSG00000118193
Uniprot IDs		Q53EQ3 Q9BSJ2	A0A384P5W4 Q15058
PDB IDs		6V6B 6V6S 6X0V 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 8Q62 8RX1 8VRD 8VRJ 8VRK 9H9P
Enriched GO Terms of Interacting Partners?			Gamma-tubulin Complex Microtubule Nucleation Cytoplasmic Microtubule Organization Cytoplasmic Microtubule Mitotic Cell Cycle Spindle Organization Microtubule Nucleator Activity Polar Microtubule Ciliary Basal Body Microtubule Gamma-tubulin Ring Complex Microtubule Cytoskeleton Organization Supramolecular Fiber Organization Microtubule Minus-end Binding Mitotic Spindle Microtubule Meiotic Spindle Organization Centrosome Pericentriolar Material Protein Serine/threonine/tyrosine Kinase Activity Non-motile Cilium Mitotic Sister Chromatid Segregation Microtubule-based Process Gamma-tubulin Binding Non-membrane Spanning Protein Tyrosine Kinase Activity Spindle Microtubule Sister Chromatid Segregation Condensed Nuclear Chromosome Nuclear Chromosome Segregation Cytoskeleton Organization Cell Leading Edge Apical Part Of Cell Structural Constituent Of Cytoskeleton Reproductive Process Mitotic Spindle Organization Microtubule Organizing Center Spindle Assembly
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