RAI2 and SGTB

Number of citations of the paper that reports this interaction (PubMedID 29892012)
71

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAI2	SGTB
Description		retinoic acid induced 2	small glutamine rich tetratricopeptide repeat co-chaperone beta
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Membrane TRC Complex
	Molecular Function	Protein Binding	Protein Binding Hsp70 Protein Binding Identical Protein Binding Protein-folding Chaperone Binding Molecular Adaptor Activity
	Biological Process	Embryo Development Ending In Birth Or Egg Hatching Animal Organ Development	Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Protein Homooligomerization Protein Heterooligomerization
Pathways
Drugs
Diseases
GWAS		Prostate-specific antigen levels ( 28139693)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intralaminar thalamic nuclei volume ( 34006833) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		13 interacting genes: APP APPL2 ATXN1 CTBP1 CTBP2 DOK5 FHL2 FXR2 SGTB TRIM55 TRIM63 UBQLN1 UBQLN4	116 interacting genes: ABCG4 ADAT2 ADIPOQ AGR2 AGR3 ASPH BTC C1QA C1QL4 C1QTNF5 C1QTNF6 C5orf46 CALR CCL3L3 CD200R1 CD3D CD68 CD79B CD99L2 CDH15 CDSN CMPK1 COL10A1 COL1A2 COLQ COMP CREB3L3 CSH1 CSH2 CTAG1A CTAG1B CYB5R1 DEFA6 DEXI DMKN ECM1 EFEMP2 EMCN ERP29 ETNK1 EVA1A FBN1 FGF21 FZD7 GALNT11 GGH GIP GPX7 GYPA HSP90B1 HSPA13 IL6R IL6ST ITPRIP ITPRIPL1 KCNE5 KRT1 LAMP3 LAT LCN2 LHB LMO2 MYDGF NAXD NME3 OSMR PAGE3 PDIA6 PGRMC1 PODXL PPIB PPIC PRAP1 PRB1 PRB3 PRB4 PRR4 PSORS1C2 RAI2 RCN1 RNASE10 RNF144A RNF144B RNF170 SDC4 SDF2L1 SELENOM SERPINE1 SERPINF1 SERPINI2 SGCA SGTA SHISA5 SIL1 SLPI SOD3 SPINK4 SPP1 SRGN SYT11 SYT4 TFF1 TMEM108 TMEM123 TMPO TMUB1 TNFRSF19 TNFSF13 TXNDC12 UBL4A UPK3A VEGFC VWC2 WFDC12 ZG16 ZG16B
Entrez ID		10742	54557
HPRD ID		02199	18049
Ensembl ID		ENSG00000131831	ENSG00000197860
Uniprot IDs		B2RBE9 B3KPD7 Q9Y5P3	Q96EQ0
PDB IDs		8ARI 8ATI
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process White Fat Cell Differentiation Viral Genome Replication Regulation Of Signal Transduction Regulation Of Long-term Neuronal Synaptic Plasticity Nucleus Negative Regulation Of Macromolecule Metabolic Process NAD Binding Amyloid-beta Complex Protein Homooligomerization Growth Cone Lamellipodium Postsynapse Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Negative Regulation Of Transcription By RNA Polymerase II Amylin Binding Positive Regulation Of Toll Signaling Pathway Visual Learning Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Cytoplasm Transcription Corepressor Activity Transcription Coregulator Binding Transcription Corepressor Binding Negative Regulation Of Store-operated Calcium Channel Activity Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Regulation Of Neuronal Synaptic Plasticity Regulation Of Primary Metabolic Process Protein Complex Oligomerization Negative Regulation Of Biosynthetic Process Visual Behavior Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Transcription Repressor Complex Regulation Of Carbohydrate Catabolic Process Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Atrial Cardiac Muscle Cell Development Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation TRC Complex Positive Regulation Of Macropinocytosis Nuclear Proteasome Complex Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of ATP Metabolic Process	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Protein Binding Collagen Trimer Endoplasmic Reticulum Chaperone Complex Endoplasmic Reticulum Extracellular Matrix Protein Folding Smooth Endoplasmic Reticulum Extracellular Matrix Structural Constituent Serine-type Endopeptidase Inhibitor Activity Sarcoplasmic Reticulum Lumen Extracellular Exosome Interleukin-6 Binding Interleukin-6 Receptor Activity Oncostatin-M Receptor Complex Melanosome Response To Bacterium Hormone Activity Interleukin-6 Receptor Complex Ciliary Neurotrophic Factor Receptor Complex Oncostatin-M Receptor Activity Positive Regulation Of Transport Memory Response To Endoplasmic Reticulum Stress Defense Response To Bacterium Ciliary Neurotrophic Factor Receptor Activity Interleukin-11 Receptor Activity Interleukin-11 Binding Oncostatin-M-mediated Signaling Pathway Regulation Of Smooth Muscle Cell-matrix Adhesion Regulation Of Immune System Process Sequestering Of Calcium Ion Biomineral Tissue Development Basement Membrane Ciliary Neurotrophic Factor-mediated Signaling Pathway ERAD Pathway Growth Factor Activity Golgi Lumen Positive Regulation Of Acute Inflammatory Response Ciliary Neurotrophic Factor Receptor Binding Response To Stress Regulation Of Cell-substrate Adhesion
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