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KHDRBS3 and INPP5D
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KHDRBS3
INPP5D
Gene Name
KH domain containing, RNA binding, signal transduction associated 3
inositol polyphosphate-5-phosphatase, 145kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Membrane
Molecular Function
RNA Binding
Protein Binding
SH3 Domain Binding
Poly(A) RNA Binding
Inositol-polyphosphate 5-phosphatase Activity
Protein Binding
SH3 Domain Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Spermatogenesis
Phospholipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
Phosphate-containing Compound Metabolic Process
Apoptotic Process
Signal Transduction
Blood Coagulation
Inositol Phosphate Metabolic Process
Small Molecule Metabolic Process
Phosphatidylinositol Dephosphorylation
T Cell Receptor Signaling Pathway
Leukocyte Migration
Pathways
Downstream TCR signaling
Metabolism of lipids and lipoproteins
Cytokine Signaling in Immune system
Inositol phosphate metabolism
PECAM1 interactions
Cell surface interactions at the vascular wall
Synthesis of PIPs at the plasma membrane
Signaling by Interleukins
TCR signaling
Interleukin receptor SHC signaling
Synthesis of IP3 and IP4 in the cytosol
Interleukin receptor SHC signaling
Interleukin-2 signaling
Phospholipid metabolism
Interleukin-3, 5 and GM-CSF signaling
PI Metabolism
Adaptive Immune System
Drugs
Diseases
GWAS
Crohn's disease (
22412388
23128233
)
Protein-Protein Interactions
30 interactors:
BAHD1
CACNA1A
CCDC33
DMRT3
FUS
HNRNPC
HNRNPK
INPP5D
KHDRBS1
KHDRBS2
LNX1
MARK4
NCOA5
NELFB
NUDT18
PRMT1
PRPF31
PSMF1
PTBP2
RBBP6
RBM7
RBMX
RBMY1A1
SGSM2
SIAH1
SNRPC
SRSF9
U2AF2
YTHDC1
ZNF408
40 interactors:
ARAP1
CD22
CD300LF
CRKL
CSF1R
CSF3R
DAB1
DAB2
DOK1
DOK2
DOK3
EPOR
FCGR2B
FGR
FLT3
GAB1
GAB2
GRB2
HCK
IL4R
JAK1
JAK3
KHDRBS3
KIT
KRT31
KRT40
KRTAP10-3
KRTAP10-7
KRTAP10-9
LILRB4
LYN
MET
NOTCH2NL
PECAM1
PLCG1
PTPN11
SH3KBP1
SHC1
XIAP
ZDHHC17
Entrez ID
10656
3635
HPRD ID
10007
09033
Ensembl ID
ENSG00000131773
ENSG00000168918
Uniprot IDs
O75525
Q92835
PDB IDs
2YSX
Enriched GO Terms of Interacting Partners
?
MRNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
RNA Splicing
MRNA Metabolic Process
RNA Processing
Gene Expression
RNA Metabolic Process
Negative Regulation Of RNA Splicing
Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of RNA Splicing
MRNA Splice Site Selection
Spliceosomal Complex Assembly
Negative Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of MRNA Splicing, Via Spliceosome
Ribonucleoprotein Complex Assembly
Regulation Of MRNA Processing
Metabolic Process
Regulation Of Metabolic Process
Ribonucleoprotein Complex Biogenesis
Regulation Of Gene Expression
Transcription, DNA-templated
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
RNA Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Cellular Component Assembly
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Negative Regulation Of Gene Expression
Cellular Macromolecular Complex Assembly
Positive Regulation Of RNA Splicing
Spliceosomal SnRNP Assembly
Termination Of RNA Polymerase II Transcription
Cerebellar Molecular Layer Development
DGDP Catabolic Process
DADP Catabolic Process
GDP Catabolic Process
Adult Walking Behavior
Cellular Process
Cellular Macromolecule Biosynthetic Process
Ventral Spinal Cord Development
Transmission Of Nerve Impulse
Macromolecule Biosynthetic Process
Vestibular Nucleus Development
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Signal Transduction
Signaling
Cell Communication
Immune System Process
Cell Migration
Positive Regulation Of Signal Transduction
Cell Motility
Intracellular Signal Transduction
Cell Surface Receptor Signaling Pathway
Cellular Response To Stimulus
Regulation Of Immune System Process
Positive Regulation Of Kinase Activity
Regulation Of Signal Transduction
Locomotion
Regulation Of Immune Response
Positive Regulation Of Transferase Activity
Leukocyte Migration
Cytokine-mediated Signaling Pathway
Regulation Of Signaling
Cellular Response To Organic Substance
Positive Regulation Of Intracellular Signal Transduction
Fc Receptor Signaling Pathway
Peptidyl-tyrosine Phosphorylation
Movement Of Cell Or Subcellular Component
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Phosphorylation
Response To Cytokine
Response To Stimulus
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Protein Modification Process
Protein Autophosphorylation
Regulation Of Protein Kinase Activity
Cellular Response To Cytokine Stimulus
Response To Organic Substance
Positive Regulation Of Protein Kinase Activity
Regulation Of MAPK Cascade
Regulation Of Kinase Activity
Innate Immune Response
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Protein Phosphorylation
Immune Response
Regulation Of Phosphorylation
Defense Response
Positive Regulation Of Cellular Protein Metabolic Process
Cellular Response To Hormone Stimulus
Cellular Response To Peptide Hormone Stimulus
Positive Regulation Of MAPK Cascade
Cellular Response To Peptide
Tagcloud
?
cytoskeleton
dataset
deposited
dysregulation
exerts
expand
heterodimeric
http
identifier
inositol
mapkapk2
nad
nadk
nonreceptor
org
pertaining
phosphatases
phosphoproteome
phosphoproteomic
polyphosphate
proteomecentral
proteomexchange
ptpn12
pxd000984
reorganization
ripk1
silac
threonine
tnfrsf
Tagcloud (Difference)
?
cytoskeleton
dataset
deposited
dysregulation
exerts
expand
heterodimeric
http
identifier
inositol
mapkapk2
nad
nadk
nonreceptor
org
pertaining
phosphatases
phosphoproteome
phosphoproteomic
polyphosphate
proteomecentral
proteomexchange
ptpn12
pxd000984
reorganization
ripk1
silac
threonine
tnfrsf
Tagcloud (Intersection)
?