KHDRBS3 and SNX18

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KHDRBS3	SNX18
Description		KH RNA binding domain containing, signal transduction associated 3	sorting nexin 18
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Protein-containing Complex	Endosome Plasma Membrane Cytoplasmic Side Of Plasma Membrane Endosome Membrane Endomembrane System Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Phosphatidylinositol Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome	Mitotic Cell Cycle Mitotic Cytokinesis Endocytosis Positive Regulation Of Catabolic Process Protein Transport Endosomal Transport Cleavage Furrow Formation Positive Regulation Of GTPase Activity Cell Division Plasma Membrane Tubulation Positive Regulation Of Autophagosome Assembly
Pathways		PTK6 Regulates Proteins Involved in RNA Processing	Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Chronotype ( 30696823) Colorectal cancer ( 34062886) Disease progression in age-related macular degeneration ( 29346644) Polycystic ovary syndrome ( 25574032) Squamous cell lung carcinoma ( 28604730) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Immune response to smallpox vaccine (IL-6) ( 22542470)
Interacting Genes		59 interacting genes: AQP1 BAHD1 CACNA1A CCDC187 CCDC33 CNNM3 CPSF7 DMRT3 DOCK2 FBXO7 FUS FXR1 HBZ HNRNPC HNRNPK HNRNPR INPP5D KHDRBS1 KHDRBS2 LMNTD2 LNX1 MARK4 MYPOP NCOA5 NELFB NUDT18 OGT PCDHB14 PPP1R13B PRMT1 PRPF31 PRR3 PSMA1 PSMF1 PTBP2 RASAL3 RASD1 RBBP6 RBM3 RBM7 RBMX RBMY1A1 RFC3 RPH3AL SGSM2 SIAH1 SNRPC SNX18 SRSF9 TSGA10IP TYK2 U2AF2 WWP2 YTHDC1 ZNF326 ZNF408 ZNF575 ZNF580 ZNF688	19 interacting genes: ABI2 CPSF7 CYSRT1 DPPA4 GABARAP GOLGA2 HSF2BP HSPB2 HSPB2-C11orf52 KHDRBS3 KRTAP1-1 KRTAP6-3 MAP1LC3B MDFI MSS51 PTPN21 SOS1 SOS2 ZBTB42
Entrez ID		10656	112574
HPRD ID		10007	15407
Ensembl ID		ENSG00000131773	ENSG00000178996
Uniprot IDs		O75525	Q96RF0
PDB IDs		5EL3 5ELR 5ELS 5ELT 5EMO
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Splicing MRNA Processing Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing Regulation Of MRNA Processing RNA Processing MRNA Binding RNA Binding Regulation Of MRNA Metabolic Process MRNA Metabolic Process Spliceosomal Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Regulation Of RNA Metabolic Process Nucleus Negative Regulation Of MRNA Splicing, Via Spliceosome MRNA Splice Site Recognition Nucleic Acid Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of RNA Splicing Negative Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Poly(U) RNA Binding Protein-RNA Complex Assembly MRNA Alternative Polyadenylation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Gene Expression Commitment Complex Positive Regulation Of MRNA Splicing, Via Spliceosome Nucleoplasm Positive Regulation Of NK T Cell Proliferation Positive Regulation Of Translation Catalytic Step 2 Spliceosome Protein-containing Complex Assembly Positive Regulation Of NK T Cell Activation Protein Binding	Regulation Of Pro-B Cell Differentiation Regulation Of Lymphoid Progenitor Cell Differentiation Mitophagy Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding SH3 Domain Binding Regulation Of T Cell Differentiation In Thymus B Cell Homeostasis Macroautophagy Regulation Of Hematopoietic Progenitor Cell Differentiation
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