NOP56 and FILNC1

Number of citations of the paper that reports this interaction (PubMedID 28978906)
44

Data Source:
BioGRID (unspecified method)

		NOP56	FILNC1
Description		NOP56 ribonucleoprotein	FOXO induced long non-coding RNA 1
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Sno(s)RNA-containing Ribonucleoprotein Complex Cytoplasm Membrane Box C/D Methylation Guide SnoRNP Complex Small-subunit Processome Pre-snoRNP Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding SnoRNA Binding Cadherin Binding Histone Methyltransferase Binding
	Biological Process	RRNA Processing Ribosome Biogenesis Ribosomal Small Subunit Biogenesis
Pathways		Association of TriC/CCT with target proteins during biosynthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS			Heel bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		9 interacting genes: BMPR2 CSNK2A1 DYNC1LI1 FILNC1 KLF6 PTEN SDCBP2 TCOF1 UBE2I	88 interacting genes: AAAS ABCC1 ACTN1 ACTR2 AHSA1 AIMP2 AKAP8 ALDH1B1 AP1B1 AP3D1 ARAP1 ARF6 ATP2A2 CAND1 CCT6B CLPX CNDP2 COPG1 DDX24 DNM1 DNM1L DPM1 DYNC1H1 EEF1D EEF2 ERLIN1 GALK1 GMPS GSTO1 HDLBP HNRNPA0 HNRNPD HSPA1A IDH1 KTN1 LAMC1 LAS1L MAP1S MCM3 MRPL4 MSH2 MTHFD1L MYL12A NIBAN2 NKRF NOP56 NPEPPSP1 NSF NUP153 OASL OGT PCAT1 PDCD4 PES1 PFAS PLS3 PPME1 PSMC2 PSMC4 PSMD14 PSMD5 PURA QNG1 RIGI RO60 RPL13A RPS5 RPSA SART1 STT3B STXBP2 TAGLN2 TIMM50 TMEM126A TMX3 TRIP13 TTLL12 TTN U2AF1 UBA52 UBE4A VPS35 WARS1 XPO1 XPOT XRCC6 YWHAB ZCCHC8
Entrez ID		10528	100132735
HPRD ID		10119
Ensembl ID		ENSG00000101361	ENSG00000231426
Uniprot IDs		O00567
PDB IDs		7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?		PML Body Regulation Of Smooth Muscle Cell Proliferation Osteoblast Differentiation Positive Regulation Of Signal Transduction Nucleoplasm Positive Regulation Of Cell Communication Regulation Of Osteoblast Differentiation Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Chondrocyte Proliferation Regulation Of Lung Blood Pressure Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Axonogenesis Regulation Of Intracellular Signal Transduction Pulmonary Valve Development Tricuspid Valve Morphogenesis Venous Blood Vessel Development Positive Regulation Of Signaling Regulation Of Epithelial Cell Migration System Development Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Activin Receptor Activity, Type II Regulation Of Chromosome Segregation Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Aggrephagy Regulation Of Cell Cycle Phase Transition Intracellular Transport Regulation Of Chromosome Separation Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Membrane Assembly Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol Phosphate Phosphatase Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Nucleolar Large RRNA Transcription By RNA Polymerase I RING-like Zinc Finger Domain Binding SUMO Ligase Complex Small Protein Activating Enzyme Binding HLH Domain Binding SUMO Conjugating Enzyme Activity Early Endosome To Recycling Endosome Transport Positive Regulation Of Cell Growth Positive Regulation Of Axon Extension Involved In Axon Guidance	RNA Binding Cytosol ATP Hydrolysis Activity Nucleotide Binding Cadherin Binding Ribonucleoprotein Complex Ficolin-1-rich Granule Lumen ATP Binding Extracellular Exosome Proteasome Accessory Complex Cytoplasm Translation Intracellular Transport Proteasome Regulatory Particle, Base Subcomplex Secretory Granule Lumen Nucleoplasm Actin Filament Binding Macromolecule Metabolic Process Nucleolus Mitochondrion-derived Vesicle Intracellular Protein Transport Organelle Localization Cellular Localization Establishment Of Localization In Cell Proteasome Complex Nucleobase-containing Compound Metabolic Process Actin Filament Network Formation ATP-dependent Protein Disaggregase Activity Proteasome-activating Activity LncRNA Binding Membrane Coat Ribosome Cytoplasmic Translation Establishment Of Organelle Localization Double-stranded DNA Binding Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Establishment Of Protein Localization ATP-dependent Protein Folding Chaperone Cellular Component Assembly Regulation Of Cytoplasmic Translation
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