FILNC1 and ALDH1B1

Number of citations of the paper that reports this interaction (PubMedID 28978906)
44

Data Source:
BioGRID (unspecified method)

		FILNC1	ALDH1B1
Description		FOXO induced long non-coding RNA 1	aldehyde dehydrogenase 1 family member B1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function		Aldehyde Dehydrogenase (NAD+) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor NAD Binding
	Biological Process		Carbohydrate Metabolic Process Ethanol Catabolic Process Aldehyde Metabolic Process
Pathways			Ethanol oxidation Mitochondrial protein degradation
Drugs			NADH
Diseases
GWAS		Heel bone mineral density x serum urate levels interaction ( 34046847)	Alcohol consumption (drinkers vs non-drinkers) ( 31959922) Clostridioides difficle infection in antibiotics-users ( 33841421) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Longevity (100 years and older) ( 33948810) Metabolite levels ( 23823483) Pulse pressure ( 27841878) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure ( 27841878) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		88 interacting genes: AAAS ABCC1 ACTN1 ACTR2 AHSA1 AIMP2 AKAP8 ALDH1B1 AP1B1 AP3D1 ARAP1 ARF6 ATP2A2 CAND1 CCT6B CLPX CNDP2 COPG1 DDX24 DNM1 DNM1L DPM1 DYNC1H1 EEF1D EEF2 ERLIN1 GALK1 GMPS GSTO1 HDLBP HNRNPA0 HNRNPD HSPA1A IDH1 KTN1 LAMC1 LAS1L MAP1S MCM3 MRPL4 MSH2 MTHFD1L MYL12A NIBAN2 NKRF NOP56 NPEPPSP1 NSF NUP153 OASL OGT PCAT1 PDCD4 PES1 PFAS PLS3 PPME1 PSMC2 PSMC4 PSMD14 PSMD5 PURA QNG1 RIGI RO60 RPL13A RPS5 RPSA SART1 STT3B STXBP2 TAGLN2 TIMM50 TMEM126A TMX3 TRIP13 TTLL12 TTN U2AF1 UBA52 UBE4A VPS35 WARS1 XPO1 XPOT XRCC6 YWHAB ZCCHC8	5 interacting genes: EXOSC10 FABP2 FILNC1 OGT XRN2
Entrez ID		100132735	219
HPRD ID			00005
Ensembl ID		ENSG00000231426	ENSG00000137124
Uniprot IDs			A0A384MTJ7 P30837
PDB IDs			7MJC 7MJD 7RAD
Enriched GO Terms of Interacting Partners?		RNA Binding Cytosol ATP Hydrolysis Activity Nucleotide Binding Cadherin Binding Ribonucleoprotein Complex Ficolin-1-rich Granule Lumen ATP Binding Extracellular Exosome Proteasome Accessory Complex Cytoplasm Translation Intracellular Transport Proteasome Regulatory Particle, Base Subcomplex Secretory Granule Lumen Nucleoplasm Actin Filament Binding Macromolecule Metabolic Process Nucleolus Mitochondrion-derived Vesicle Intracellular Protein Transport Organelle Localization Cellular Localization Establishment Of Localization In Cell Proteasome Complex Nucleobase-containing Compound Metabolic Process Actin Filament Network Formation ATP-dependent Protein Disaggregase Activity Proteasome-activating Activity LncRNA Binding Membrane Coat Ribosome Cytoplasmic Translation Establishment Of Organelle Localization Double-stranded DNA Binding Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Establishment Of Protein Localization ATP-dependent Protein Folding Chaperone Cellular Component Assembly Regulation Of Cytoplasmic Translation	Cellular Response To Nutrient 3'-5'-RNA Exonuclease Activity Lipid Binding Exonuclease Activity Nuclear Polyadenylation-dependent Antisense Transcript Catabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Nuclear Polyadenylation-dependent SnoRNA Catabolic Process Nuclear Polyadenylation-dependent SnRNA Catabolic Process Nuclear Polyadenylation-dependent CUT Catabolic Process Nuclease Activity Nuclear-transcribed MRNA Catabolic Process Transcription Termination Site Sequence-specific DNA Binding MRNA Catabolic Process Apical Cortex Long-chain Fatty Acid Binding Response To Nutrient Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRNA Surveillance RNA Catabolic Process SnRNA Catabolic Process TRAMP-dependent TRNA Surveillance Pathway RRNA Processing Nuclear Polyadenylation-dependent RRNA Catabolic Process Sno(s)RNA Catabolic Process Positive Regulation Of MRNA Cis Splicing, Via Spliceosome CUT Catabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Termination Of RNA Polymerase II Transcription 5'-3' RNA Exonuclease Activity Poly(A)-dependent SnoRNA 3'-end Processing RRNA Metabolic Process Positive Regulation Of Monocyte Differentiation Cellular Response To Nutrient Levels RRNA 3'-end Processing Nucleolar Exosome (RNase Complex) Regulation Of Transcription By Glucose 5'-3' Exonuclease Activity Cellular Response To Vitamin D TRNA Decay Nuclear MRNA Surveillance NSL Complex Myoblast Proliferation Regulation Of Telomerase RNA Localization To Cajal Body Intestinal Lipid Absorption
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