FILNC1 and PES1

Number of citations of the paper that reports this interaction (PubMedID 28978906)
44

Data Source:
BioGRID (unspecified method)

		FILNC1	PES1
Description		FOXO induced long non-coding RNA 1	pescadillo ribosomal biogenesis factor 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Membrane Preribosome, Large Subunit Precursor PeBoW Complex
	Molecular Function		RNA Binding Protein Binding Ribonucleoprotein Complex Binding
	Biological Process		Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Cell Population Proliferation Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Regulation Of Cell Cycle
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Heel bone mineral density x serum urate levels interaction ( 34046847)	Gut microbiota relative abundance (Blautia) ( 33208821)
Interacting Genes		88 interacting genes: AAAS ABCC1 ACTN1 ACTR2 AHSA1 AIMP2 AKAP8 ALDH1B1 AP1B1 AP3D1 ARAP1 ARF6 ATP2A2 CAND1 CCT6B CLPX CNDP2 COPG1 DDX24 DNM1 DNM1L DPM1 DYNC1H1 EEF1D EEF2 ERLIN1 GALK1 GMPS GSTO1 HDLBP HNRNPA0 HNRNPD HSPA1A IDH1 KTN1 LAMC1 LAS1L MAP1S MCM3 MRPL4 MSH2 MTHFD1L MYL12A NIBAN2 NKRF NOP56 NPEPPSP1 NSF NUP153 OASL OGT PCAT1 PDCD4 PES1 PFAS PLS3 PPME1 PSMC2 PSMC4 PSMD14 PSMD5 PURA QNG1 RIGI RO60 RPL13A RPS5 RPSA SART1 STT3B STXBP2 TAGLN2 TIMM50 TMEM126A TMX3 TRIP13 TTLL12 TTN U2AF1 UBA52 UBE4A VPS35 WARS1 XPO1 XPOT XRCC6 YWHAB ZCCHC8	5 interacting genes: APP BOP1 CEBPA FILNC1 USP7
Entrez ID		100132735	23481
HPRD ID			05783
Ensembl ID		ENSG00000231426	ENSG00000100029
Uniprot IDs			B2RDF2 B3KTZ6 F6VXF5 O00541
PDB IDs			2EP8 8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL2 8FL3 8FL4 8FL6 8FL7 8FLA 8FLB 8FLD 8FLE 8INE 8INF 8IPX 8IPY 8IR3
Enriched GO Terms of Interacting Partners?		RNA Binding Cytosol ATP Hydrolysis Activity Nucleotide Binding Cadherin Binding Ribonucleoprotein Complex Ficolin-1-rich Granule Lumen ATP Binding Extracellular Exosome Proteasome Accessory Complex Cytoplasm Translation Intracellular Transport Proteasome Regulatory Particle, Base Subcomplex Secretory Granule Lumen Nucleoplasm Actin Filament Binding Macromolecule Metabolic Process Nucleolus Mitochondrion-derived Vesicle Intracellular Protein Transport Organelle Localization Cellular Localization Establishment Of Localization In Cell Proteasome Complex Nucleobase-containing Compound Metabolic Process Actin Filament Network Formation ATP-dependent Protein Disaggregase Activity Proteasome-activating Activity LncRNA Binding Membrane Coat Ribosome Cytoplasmic Translation Establishment Of Organelle Localization Double-stranded DNA Binding Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Establishment Of Protein Localization ATP-dependent Protein Folding Chaperone Cellular Component Assembly Regulation Of Cytoplasmic Translation	Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Positive Regulation Of Inflammatory Response Regulation Of Response To Calcium Ion Developmental Maturation Axon Midline Choice Point Recognition Amylin Binding Positive Regulation Of Protein Catabolic Process Regulation Of Proteolysis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Protein Catabolic Process Protein-containing Complex Lipoprotein Particle Memory Growth Factor Receptor Binding Main Axon Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Metal Ion Low-density Lipoprotein Particle Mediated Signaling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process CHOP-C/EBP Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 White Fat Cell Proliferation C/EBP Complex Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Symbiont-mediated Disruption Of Host Cell PML Body
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