FILNC1 and SART1

Number of citations of the paper that reports this interaction (PubMedID 28978906)
44

Data Source:
BioGRID (unspecified method)

		FILNC1	SART1
Description		FOXO induced long non-coding RNA 1	spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Golgi Apparatus Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function		RNA Binding Protein Binding
	Biological Process		Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Maturation Of 5S RRNA MRNA Processing RNA Splicing MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Cytotoxic T Cell Differentiation
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Heel bone mineral density x serum urate levels interaction ( 34046847)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		88 interacting genes: AAAS ABCC1 ACTN1 ACTR2 AHSA1 AIMP2 AKAP8 ALDH1B1 AP1B1 AP3D1 ARAP1 ARF6 ATP2A2 CAND1 CCT6B CLPX CNDP2 COPG1 DDX24 DNM1 DNM1L DPM1 DYNC1H1 EEF1D EEF2 ERLIN1 GALK1 GMPS GSTO1 HDLBP HNRNPA0 HNRNPD HSPA1A IDH1 KTN1 LAMC1 LAS1L MAP1S MCM3 MRPL4 MSH2 MTHFD1L MYL12A NIBAN2 NKRF NOP56 NPEPPSP1 NSF NUP153 OASL OGT PCAT1 PDCD4 PES1 PFAS PLS3 PPME1 PSMC2 PSMC4 PSMD14 PSMD5 PURA QNG1 RIGI RO60 RPL13A RPS5 RPSA SART1 STT3B STXBP2 TAGLN2 TIMM50 TMEM126A TMX3 TRIP13 TTLL12 TTN U2AF1 UBA52 UBE4A VPS35 WARS1 XPO1 XPOT XRCC6 YWHAB ZCCHC8	16 interacting genes: APP CEBPA CHERP FILNC1 HSF2BP IGHE RNF10 SNW1 SRPK2 SRSF4 SUMO2 UBC UBE2I UBL5 WBP4 ZCCHC10
Entrez ID		100132735	9092
HPRD ID			10440
Ensembl ID		ENSG00000231426	ENSG00000175467
Uniprot IDs			O43290
PDB IDs			4PYU 5O9Z 6AHD 6QW6 6QX9 8H6E 8H6J 8H6K 8H6L 8Q7N 8QO9 8QOZ 8QP8 8QP9 8QPA 8QPB 8QPE 8QPK 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 8Y6O
Enriched GO Terms of Interacting Partners?		RNA Binding Cytosol ATP Hydrolysis Activity Nucleotide Binding Cadherin Binding Ribonucleoprotein Complex Ficolin-1-rich Granule Lumen ATP Binding Extracellular Exosome Proteasome Accessory Complex Cytoplasm Translation Intracellular Transport Proteasome Regulatory Particle, Base Subcomplex Secretory Granule Lumen Nucleoplasm Actin Filament Binding Macromolecule Metabolic Process Nucleolus Mitochondrion-derived Vesicle Intracellular Protein Transport Organelle Localization Cellular Localization Establishment Of Localization In Cell Proteasome Complex Nucleobase-containing Compound Metabolic Process Actin Filament Network Formation ATP-dependent Protein Disaggregase Activity Proteasome-activating Activity LncRNA Binding Membrane Coat Ribosome Cytoplasmic Translation Establishment Of Organelle Localization Double-stranded DNA Binding Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Establishment Of Protein Localization ATP-dependent Protein Folding Chaperone Cellular Component Assembly Regulation Of Cytoplasmic Translation	Protein Tag Activity Macromolecule Metabolic Process MRNA Processing RNA Binding RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing Regulation Of MRNA Splicing, Via Spliceosome SUMO Transferase Activity RNA Metabolic Process MRNA Metabolic Process Nucleoplasm Regulation Of MRNA Processing Presynaptic Cytosol Postsynaptic Cytosol Regulation Of Proteolysis Protein Modification Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Macrophage Differentiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding IgE B Cell Receptor Complex Nuclear Speck Regulation Of RNA Splicing SUMO Conjugating Enzyme Activity MRNA Splicing, Via Spliceosome Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Protein Sumoylation Positive Regulation Of Calcium-mediated Signaling Presynapse Acetylcholine Receptor Activator Activity Macrophage Activation Antibacterial Humoral Response Lipoprotein Particle Positive Regulation Of Protein Import Response To Vitamin B2 C/EBP Complex Acute Inflammatory Response Nucleic Acid Metabolic Process Primary Adaptive Immune Response B Cell Antigen Processing And Presentation Type I Hypersensitivity Glutamatergic Synapse Nucleic Acid Binding Positive Regulation Of Neuron Apoptotic Process PTB Domain Binding
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