FILNC1 and CLPX

Number of citations of the paper that reports this interaction (PubMedID 28978906)
44

Data Source:
BioGRID (unspecified method)

		FILNC1	CLPX
Description		FOXO induced long non-coding RNA 1	caseinolytic mitochondrial matrix peptidase chaperone subunit X
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol Endopeptidase Clp Complex Mitochondrial Endopeptidase Clp Complex Mitochondrial Nucleoid
	Molecular Function		Nucleotide Binding ATP-dependent Peptidase Activity Protein Binding ATP Binding Zinc Ion Binding Peptidase Activator Activity Hydrolase Activity ATP Hydrolysis Activity Metal Ion Binding Protein Dimerization Activity Unfolded Protein Binding ATP-dependent Protein Folding Chaperone
	Biological Process		Protein Folding Proteolysis ATP Metabolic Process Proteolysis Involved In Protein Catabolic Process
Pathways			Mitochondrial protein degradation
Drugs
Diseases
GWAS		Heel bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		88 interacting genes: AAAS ABCC1 ACTN1 ACTR2 AHSA1 AIMP2 AKAP8 ALDH1B1 AP1B1 AP3D1 ARAP1 ARF6 ATP2A2 CAND1 CCT6B CLPX CNDP2 COPG1 DDX24 DNM1 DNM1L DPM1 DYNC1H1 EEF1D EEF2 ERLIN1 GALK1 GMPS GSTO1 HDLBP HNRNPA0 HNRNPD HSPA1A IDH1 KTN1 LAMC1 LAS1L MAP1S MCM3 MRPL4 MSH2 MTHFD1L MYL12A NIBAN2 NKRF NOP56 NPEPPSP1 NSF NUP153 OASL OGT PCAT1 PDCD4 PES1 PFAS PLS3 PPME1 PSMC2 PSMC4 PSMD14 PSMD5 PURA QNG1 RIGI RO60 RPL13A RPS5 RPSA SART1 STT3B STXBP2 TAGLN2 TIMM50 TMEM126A TMX3 TRIP13 TTLL12 TTN U2AF1 UBA52 UBE4A VPS35 WARS1 XPO1 XPOT XRCC6 YWHAB ZCCHC8	4 interacting genes: CLPP FBXL17 FILNC1 OGT
Entrez ID		100132735	10845
HPRD ID			07478
Ensembl ID		ENSG00000231426	ENSG00000166855
Uniprot IDs			O76031
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Cytosol ATP Hydrolysis Activity Nucleotide Binding Cadherin Binding Ribonucleoprotein Complex Ficolin-1-rich Granule Lumen ATP Binding Extracellular Exosome Proteasome Accessory Complex Cytoplasm Translation Intracellular Transport Proteasome Regulatory Particle, Base Subcomplex Secretory Granule Lumen Nucleoplasm Actin Filament Binding Macromolecule Metabolic Process Nucleolus Mitochondrion-derived Vesicle Intracellular Protein Transport Organelle Localization Cellular Localization Establishment Of Localization In Cell Proteasome Complex Nucleobase-containing Compound Metabolic Process Actin Filament Network Formation ATP-dependent Protein Disaggregase Activity Proteasome-activating Activity LncRNA Binding Membrane Coat Ribosome Cytoplasmic Translation Establishment Of Organelle Localization Double-stranded DNA Binding Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Establishment Of Protein Localization ATP-dependent Protein Folding Chaperone Cellular Component Assembly Regulation Of Cytoplasmic Translation	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Endopeptidase Clp Complex ATP-dependent Peptidase Activity Proteolysis Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Regulation Of Transcription By Glucose Mitochondrial Protein Catabolic Process NSL Complex Neural Crest Cell Differentiation
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