FILNC1 and OASL

Number of citations of the paper that reports this interaction (PubMedID 28978906)
44

Data Source:
BioGRID (unspecified method)

		FILNC1	OASL
Description		FOXO induced long non-coding RNA 1	2'-5'-oligoadenylate synthetase like
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane
	Molecular Function		2'-5'-oligoadenylate Synthetase Activity DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Nucleotidyltransferase Activity Nuclear Thyroid Hormone Receptor Binding
	Biological Process		Immune System Process Response To Virus Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Type I Interferon-mediated Signaling Pathway Interleukin-27-mediated Signaling Pathway Defense Response To Other Organism Antiviral Innate Immune Response Positive Regulation Of RIG-I Signaling Pathway
Pathways			Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Heel bone mineral density x serum urate levels interaction ( 34046847)	Alanine aminotransferase levels ( 33547301) C-reactive protein ( 22939635) C-reactive protein levels ( 24763700 30388399) Cardiovascular disease risk factors ( 21943158) Hematocrit ( 32888494) Hemoglobin ( 32888494) N-glycan levels ( 21203500 21908519) Serum metabolite levels ( 23093944) Type 2 diabetes ( 30054458)
Interacting Genes		88 interacting genes: AAAS ABCC1 ACTN1 ACTR2 AHSA1 AIMP2 AKAP8 ALDH1B1 AP1B1 AP3D1 ARAP1 ARF6 ATP2A2 CAND1 CCT6B CLPX CNDP2 COPG1 DDX24 DNM1 DNM1L DPM1 DYNC1H1 EEF1D EEF2 ERLIN1 GALK1 GMPS GSTO1 HDLBP HNRNPA0 HNRNPD HSPA1A IDH1 KTN1 LAMC1 LAS1L MAP1S MCM3 MRPL4 MSH2 MTHFD1L MYL12A NIBAN2 NKRF NOP56 NPEPPSP1 NSF NUP153 OASL OGT PCAT1 PDCD4 PES1 PFAS PLS3 PPME1 PSMC2 PSMC4 PSMD14 PSMD5 PURA QNG1 RIGI RO60 RPL13A RPS5 RPSA SART1 STT3B STXBP2 TAGLN2 TIMM50 TMEM126A TMX3 TRIP13 TTLL12 TTN U2AF1 UBA52 UBE4A VPS35 WARS1 XPO1 XPOT XRCC6 YWHAB ZCCHC8	4 interacting genes: FILNC1 MBD1 SEZ6L2 THRA
Entrez ID		100132735	8638
HPRD ID			04473
Ensembl ID		ENSG00000231426	ENSG00000135114
Uniprot IDs			A0A7P0T9H8 Q15646
PDB IDs			1WH3 4XQ7
Enriched GO Terms of Interacting Partners?		RNA Binding Cytosol ATP Hydrolysis Activity Nucleotide Binding Cadherin Binding Ribonucleoprotein Complex Ficolin-1-rich Granule Lumen ATP Binding Extracellular Exosome Proteasome Accessory Complex Cytoplasm Translation Intracellular Transport Proteasome Regulatory Particle, Base Subcomplex Secretory Granule Lumen Nucleoplasm Actin Filament Binding Macromolecule Metabolic Process Nucleolus Mitochondrion-derived Vesicle Intracellular Protein Transport Organelle Localization Cellular Localization Establishment Of Localization In Cell Proteasome Complex Nucleobase-containing Compound Metabolic Process Actin Filament Network Formation ATP-dependent Protein Disaggregase Activity Proteasome-activating Activity LncRNA Binding Membrane Coat Ribosome Cytoplasmic Translation Establishment Of Organelle Localization Double-stranded DNA Binding Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Establishment Of Protein Localization ATP-dependent Protein Folding Chaperone Cellular Component Assembly Regulation Of Cytoplasmic Translation	Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Thyroid Hormone Receptor Signaling Pathway Female Courtship Behavior Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Positive Regulation Of Female Receptivity Double-stranded Methylated DNA Binding Unmethylated CpG Binding Transcription By RNA Polymerase II Regulation Of Female Receptivity Regulation Of Thyroid Hormone Receptor Signaling Pathway Type I Pneumocyte Differentiation Female Mating Behavior Negative Regulation Of DNA-templated Transcription Initiation Thyroid Hormone Binding Negative Regulation Of Transcription Initiation By RNA Polymerase II Cerebellar Purkinje Cell Layer Development General Transcription Initiation Factor Binding DNA-templated Transcription Synapse Maturation Cell Aggregation Cartilage Condensation Mating Behavior Retinoic Acid Receptor Signaling Pathway Methyl-CpG Binding Lung Epithelial Cell Differentiation TBP-class Protein Binding Lung Cell Differentiation Thyroid Gland Development Regulation Of Myeloid Cell Apoptotic Process Reproductive Behavior DNA Methylation-dependent Constitutive Heterochromatin Formation Response To Cold
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