FILNC1 and RPS5

Number of citations of the paper that reports this interaction (PubMedID 28978906)
44

Data Source:
BioGRID (unspecified method)

		FILNC1	RPS5
Description		FOXO induced long non-coding RNA 1	ribosomal protein S5
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Small Ribosomal Subunit Membrane Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Small-subunit Processome Synapse Extracellular Exosome Ribonucleoprotein Complex
	Molecular Function		RNA Binding MRNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding
	Biological Process		Cytoplasmic Translation Translation Translational Initiation Regulation Of Translational Fidelity Ribosomal Small Subunit Biogenesis
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs			Artenimol
Diseases
GWAS		Heel bone mineral density x serum urate levels interaction ( 34046847)	Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821)
Interacting Genes		88 interacting genes: AAAS ABCC1 ACTN1 ACTR2 AHSA1 AIMP2 AKAP8 ALDH1B1 AP1B1 AP3D1 ARAP1 ARF6 ATP2A2 CAND1 CCT6B CLPX CNDP2 COPG1 DDX24 DNM1 DNM1L DPM1 DYNC1H1 EEF1D EEF2 ERLIN1 GALK1 GMPS GSTO1 HDLBP HNRNPA0 HNRNPD HSPA1A IDH1 KTN1 LAMC1 LAS1L MAP1S MCM3 MRPL4 MSH2 MTHFD1L MYL12A NIBAN2 NKRF NOP56 NPEPPSP1 NSF NUP153 OASL OGT PCAT1 PDCD4 PES1 PFAS PLS3 PPME1 PSMC2 PSMC4 PSMD14 PSMD5 PURA QNG1 RIGI RO60 RPL13A RPS5 RPSA SART1 STT3B STXBP2 TAGLN2 TIMM50 TMEM126A TMX3 TRIP13 TTLL12 TTN U2AF1 UBA52 UBE4A VPS35 WARS1 XPO1 XPOT XRCC6 YWHAB ZCCHC8	4 interacting genes: FILNC1 MDM2 MYCBP2 PTEN
Entrez ID		100132735	6193
HPRD ID			04695
Ensembl ID		ENSG00000231426	ENSG00000083845
Uniprot IDs			P46782
PDB IDs			4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBS 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOL 6ZON 6ZP4 6ZUO 6ZV6 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I 7MQ8 7MQ9 7MQA 7QP6 7QP7 7R4X 7TQL 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 7XNX 7XNY 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8PPL 8QOI 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 8ZDC 8ZDD 9BKD 9BLN 9C3H 9G8M 9G8O
Enriched GO Terms of Interacting Partners?		RNA Binding Cytosol ATP Hydrolysis Activity Nucleotide Binding Cadherin Binding Ribonucleoprotein Complex Ficolin-1-rich Granule Lumen ATP Binding Extracellular Exosome Proteasome Accessory Complex Cytoplasm Translation Intracellular Transport Proteasome Regulatory Particle, Base Subcomplex Secretory Granule Lumen Nucleoplasm Actin Filament Binding Macromolecule Metabolic Process Nucleolus Mitochondrion-derived Vesicle Intracellular Protein Transport Organelle Localization Cellular Localization Establishment Of Localization In Cell Proteasome Complex Nucleobase-containing Compound Metabolic Process Actin Filament Network Formation ATP-dependent Protein Disaggregase Activity Proteasome-activating Activity LncRNA Binding Membrane Coat Ribosome Cytoplasmic Translation Establishment Of Organelle Localization Double-stranded DNA Binding Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Establishment Of Protein Localization ATP-dependent Protein Folding Chaperone Cellular Component Assembly Regulation Of Cytoplasmic Translation	Enzyme Binding Regulation Of Locomotion Response To Vitamin Regulation Of Developmental Process Regulation Of Protein Stability Regulation Of Cell Projection Organization Response To Formaldehyde Cellular Response To Vitamin B1 Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Regulation Of Neuron Projection Development Negative Regulation Of Synaptic Vesicle Clustering Central Nervous System Neuron Axonogenesis Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of Protein Kinase C Signaling Response To Cobalamin Beta-catenin Binding Regulation Of Plasma Membrane Bounded Cell Projection Organization Response To Vitamin B1 Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Response To Water-immersion Restraint Stress Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Cellular Response To Actinomycin D Negative Regulation Of Neuron Projection Development Negative Regulation Of Protein Metabolic Process Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Central Nervous System Myelin Maintenance Circadian Rhythm Rhythmic Synaptic Transmission Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Response To Nutrient Regulation Of Smooth Muscle Cell Proliferation Regulation Of Protein Kinase C Signaling Positive Regulation Of Metabolic Process Response To Erythropoietin Intracellular Signal Transduction Cellular Response To Erythropoietin NEDD8 Ligase Activity Response To Actinomycin D Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Ubiquitin-dependent Protein Catabolic Process Traversing Start Control Point Of Mitotic Cell Cycle Cellular Response To UV-C Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Negative Regulation Of Cell Projection Organization Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity
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