FILNC1 and STXBP2

Number of citations of the paper that reports this interaction (PubMedID 28978906)
44

Data Source:
BioGRID (unspecified method)

		FILNC1	STXBP2
Description		FOXO induced long non-coding RNA 1	syntaxin binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component		Extracellular Region Cytosol Plasma Membrane Apical Plasma Membrane Secretory Granule Specific Granule Azurophil Granule Zymogen Granule Membrane Cytolytic Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule Presynapse
	Molecular Function		Protein Binding Syntaxin-1 Binding Syntaxin Binding Syntaxin-3 Binding
	Biological Process		Leukocyte Mediated Cytotoxicity Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Protein Transport Vesicle-mediated Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation Regulated Exocytosis Cellular Response To Type II Interferon Presynaptic Dense Core Vesicle Exocytosis
Pathways			Platelet degranulation Other interleukin signaling
Drugs
Diseases
GWAS		Heel bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		88 interacting genes: AAAS ABCC1 ACTN1 ACTR2 AHSA1 AIMP2 AKAP8 ALDH1B1 AP1B1 AP3D1 ARAP1 ARF6 ATP2A2 CAND1 CCT6B CLPX CNDP2 COPG1 DDX24 DNM1 DNM1L DPM1 DYNC1H1 EEF1D EEF2 ERLIN1 GALK1 GMPS GSTO1 HDLBP HNRNPA0 HNRNPD HSPA1A IDH1 KTN1 LAMC1 LAS1L MAP1S MCM3 MRPL4 MSH2 MTHFD1L MYL12A NIBAN2 NKRF NOP56 NPEPPSP1 NSF NUP153 OASL OGT PCAT1 PDCD4 PES1 PFAS PLS3 PPME1 PSMC2 PSMC4 PSMD14 PSMD5 PURA QNG1 RIGI RO60 RPL13A RPS5 RPSA SART1 STT3B STXBP2 TAGLN2 TIMM50 TMEM126A TMX3 TRIP13 TTLL12 TTN U2AF1 UBA52 UBE4A VPS35 WARS1 XPO1 XPOT XRCC6 YWHAB ZCCHC8	14 interacting genes: DDX20 FILNC1 GEMIN2 GEMIN4 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2
Entrez ID		100132735	6813
HPRD ID			03423
Ensembl ID		ENSG00000231426	ENSG00000076944
Uniprot IDs			Q15833 Q53GF4
PDB IDs			4CCA
Enriched GO Terms of Interacting Partners?		RNA Binding Cytosol ATP Hydrolysis Activity Nucleotide Binding Cadherin Binding Ribonucleoprotein Complex Ficolin-1-rich Granule Lumen ATP Binding Extracellular Exosome Proteasome Accessory Complex Cytoplasm Translation Intracellular Transport Proteasome Regulatory Particle, Base Subcomplex Secretory Granule Lumen Nucleoplasm Actin Filament Binding Macromolecule Metabolic Process Nucleolus Mitochondrion-derived Vesicle Intracellular Protein Transport Organelle Localization Cellular Localization Establishment Of Localization In Cell Proteasome Complex Nucleobase-containing Compound Metabolic Process Actin Filament Network Formation ATP-dependent Protein Disaggregase Activity Proteasome-activating Activity LncRNA Binding Membrane Coat Ribosome Cytoplasmic Translation Establishment Of Organelle Localization Double-stranded DNA Binding Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Establishment Of Protein Localization ATP-dependent Protein Folding Chaperone Cellular Component Assembly Regulation Of Cytoplasmic Translation	SMN-Sm Protein Complex Spliceosomal SnRNP Assembly SNAP Receptor Activity SMN Complex Protein-RNA Complex Assembly Gemini Of Cajal Bodies SNARE Complex Spliceosomal Complex Assembly Small Nuclear Ribonucleoprotein Complex Protein-containing Complex Assembly RNA Splicing Exocytosis Vesicle Fusion Cellular Component Assembly Organelle Membrane Fusion Protein-containing Complex Organization 7-methylguanosine Cap Hypermethylation MRNA Processing Organelle Fusion U4 SnRNP Methylosome Vesicle Organization Membrane Fusion Vesicle Docking Specific Granule SNARE Binding MRNA Metabolic Process Organelle Localization By Membrane Tethering U1 SnRNP Secretion By Cell U5 SnRNP RNA Splicing, Via Transesterification Reactions Membrane Docking Vesicle-mediated Transport In Synapse U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2 SnRNP Secretory Granule U2-type Spliceosomal Complex Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex U2-type Catalytic Step 2 Spliceosome Secretion Synaptic Vesicle Exocytosis RNA Processing Calcium-ion Regulated Exocytosis Histone Pre-mRNA DCP Binding Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex U4/U6 X U5 Tri-snRNP Complex Neuron Projection
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