IPO11 and PLCD4

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		IPO11	PLCD4
Gene Name		importin 11	phospholipase C, delta 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Endoplasmic Reticulum Plasma Membrane Nuclear Membrane
	Molecular Function	Ran GTPase Binding Protein Transporter Activity	Phosphatidylinositol Phospholipase C Activity Signal Transducer Activity Calcium Ion Binding
	Biological Process	Ribosomal Protein Import Into Nucleus	Acrosome Reaction Lipid Catabolic Process Intracellular Signal Transduction Phosphatidylinositol Metabolic Process
Pathways
Drugs
Diseases
GWAS		Alcohol and nictotine co-dependence ( 23216389)
Protein-Protein Interactions		11 interactors: C1orf94 EIF4A2 KEAP1 NXF1 PLCD4 RAN RPL12 TRAF2 UBE2E1 UBE2E2 UBE2E3	3 interactors: APP IPO11 TRIM39
Entrez ID		51194	84812
HPRD ID		10003	07296
Ensembl ID		ENSG00000086200	ENSG00000115556
Uniprot IDs		Q9UI26	Q9BRC7
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation ISG15-protein Conjugation Catabolic Process Protein K11-linked Ubiquitination Viral Process Cellular Response To Cytokine Stimulus Response To Cytokine Positive Regulation Of Proteolysis Cellular Macromolecule Catabolic Process Positive Regulation Of Protein Binding Negative Regulation Of RNA-directed RNA Polymerase Activity Cellular Protein Metabolic Process Cytokine-mediated Signaling Pathway Nuclear Export Positive Regulation Of Binding Ribosomal Small Subunit Export From Nucleus Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Ubiquitin-independent Protein Catabolic Process Regulation Of Protein Binding Nuclear-transcribed MRNA Catabolic Process Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process MRNA Catabolic Process Protein Metabolic Process Regulation Of Proteolysis Cytoplasmic Transport RNA Catabolic Process Negative Regulation Of Glial Cell Apoptotic Process Viral Life Cycle Cellular Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Ribosomal Large Subunit Export From Nucleus Histone H2B Ubiquitination Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Ribosomal Subunit Export From Nucleus Poly(A)+ MRNA Export From Nucleus Regulation Of Cell Cycle Phase Transition Translational Initiation Positive Regulation Of Protein Homodimerization Activity Metabolic Process Cellular Response To Nitric Oxide Nucleocytoplasmic Transport Proteasomal Protein Catabolic Process Regulation Of Binding	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Ribosomal Protein Import Into Nucleus Negative Regulation Of Protein Processing Axon Choice Point Recognition Regulation Of Protein Processing Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Neuron Remodeling Cellular Copper Ion Homeostasis Regulation Of Proteolysis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Protein Metabolic Process Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Apoptotic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Programmed Cell Death Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Death Death Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development
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