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IPO11 and EIF4A2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
IPO11
EIF4A2
Gene Name
importin 11
eukaryotic translation initiation factor 4A2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Eukaryotic Translation Initiation Factor 4F Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Ran GTPase Binding
Protein Transporter Activity
Translation Initiation Factor Activity
Helicase Activity
Protein Binding
ATP Binding
ATPase Activity
Poly(A) RNA Binding
Biological Process
Ribosomal Protein Import Into Nucleus
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Nuclear-transcribed MRNA Poly(A) Tail Shortening
Translation
Translational Initiation
Regulation Of Translational Initiation
Gene Expression
Viral Process
Cytokine-mediated Signaling Pathway
Cellular Protein Metabolic Process
Negative Regulation Of RNA-directed RNA Polymerase Activity
Pathways
Translation initiation complex formation
Translation
Deadenylation of mRNA
ISG15 antiviral mechanism
Interferon Signaling
Cytokine Signaling in Immune system
L13a-mediated translational silencing of Ceruloplasmin expression
Antiviral mechanism by IFN-stimulated genes
Deadenylation-dependent mRNA decay
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Initiation
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
Cap-dependent Translation Initiation
Drugs
Diseases
GWAS
Alcohol and nictotine co-dependence (
23216389
)
Protein-Protein Interactions
11 interactors:
C1orf94
EIF4A2
KEAP1
NXF1
PLCD4
RAN
RPL12
TRAF2
UBE2E1
UBE2E2
UBE2E3
17 interactors:
BRCA1
CLNS1A
DPPA4
ECT2
EIF4G1
EIF4G2
IPO11
MDFI
NEK2
PDCD4
PFDN1
PIH1D2
SLC16A9
SSX2IP
TK1
TRIM36
TRIM39
Entrez ID
51194
1974
HPRD ID
10003
03062
Ensembl ID
ENSG00000086200
ENSG00000156976
Uniprot IDs
Q9UI26
Q14240
Q9NZE6
PDB IDs
3BOR
Enriched GO Terms of Interacting Partners
?
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
ISG15-protein Conjugation
Catabolic Process
Protein K11-linked Ubiquitination
Viral Process
Cellular Response To Cytokine Stimulus
Response To Cytokine
Positive Regulation Of Proteolysis
Cellular Macromolecule Catabolic Process
Positive Regulation Of Protein Binding
Negative Regulation Of RNA-directed RNA Polymerase Activity
Cellular Protein Metabolic Process
Cytokine-mediated Signaling Pathway
Nuclear Export
Positive Regulation Of Binding
Ribosomal Small Subunit Export From Nucleus
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Proteasomal Ubiquitin-independent Protein Catabolic Process
Regulation Of Protein Binding
Nuclear-transcribed MRNA Catabolic Process
Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
MRNA Catabolic Process
Protein Metabolic Process
Regulation Of Proteolysis
Cytoplasmic Transport
RNA Catabolic Process
Negative Regulation Of Glial Cell Apoptotic Process
Viral Life Cycle
Cellular Metabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Ribosomal Large Subunit Export From Nucleus
Histone H2B Ubiquitination
Positive Regulation Of Protein Catabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Ribosomal Subunit Export From Nucleus
Poly(A)+ MRNA Export From Nucleus
Regulation Of Cell Cycle Phase Transition
Translational Initiation
Positive Regulation Of Protein Homodimerization Activity
Metabolic Process
Cellular Response To Nitric Oxide
Nucleocytoplasmic Transport
Proteasomal Protein Catabolic Process
Regulation Of Binding
Regulation Of Cell Cycle
Centrosome Organization
Microtubule Organizing Center Organization
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Cellular Protein Metabolic Process
Regulation Of Microtubule-based Process
Regulation Of Protein Metabolic Process
Negative Regulation Of DNA Binding
Cell Death
Death
Regulation Of Centrosome Cycle
Centrosome Cycle
Positive Regulation Of Histone H4-K20 Methylation
Negative Regulation Of Centriole-centriole Cohesion
Positive Regulation Of Histone H4-K16 Acetylation
Fetal Process Involved In Parturition
Regulation Of Translational Initiation
Regulation Of JUN Kinase Activity
Skeletal Muscle Cell Proliferation
Positive Regulation Of Histone H3-K9 Acetylation
Regulation Of Chromosome Segregation
Cell Cycle
Regulation Of DNA Binding
Embryo Development Ending In Birth Or Egg Hatching
Negative Regulation Of Binding
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Regulation Of Centriole-centriole Cohesion
Microtubule Cytoskeleton Organization
Negative Regulation Of Cell Cycle
Apoptotic Process
Cellular Response To Indole-3-methanol
Regulation Of Mitotic Centrosome Separation
Programmed Cell Death
Regulation Of Cell Cycle Process
Developmental Process
Ribosomal Protein Import Into Nucleus
Intraciliary Transport Involved In Cilium Morphogenesis
Negative Regulation Of Centriole Replication
Response To Cortisol
Thymidine Metabolic Process
Cell Cycle Process
Regulation Of Cytoskeleton Organization
Response To Ionizing Radiation
Dosage Compensation By Inactivation Of X Chromosome
Deoxyribonucleoside Monophosphate Biosynthetic Process
Protein K6-linked Ubiquitination
Regulation Of JNK Cascade
Negative Regulation Of Cytoskeleton Organization
Tagcloud
?
4f
adult
biogenesis
confer
deprivation
differed
differs
eif4f
eif4g1
fetal
gestation
helicase
hepatocyte
insensitive
liver
nutrient
oligopyrimidine
preinitiation
rapamycin
refeeding
ribosome
sensing
top
tracts
translation
weights
went
Tagcloud (Difference)
?
4f
adult
biogenesis
confer
deprivation
differed
differs
eif4f
eif4g1
fetal
gestation
helicase
hepatocyte
insensitive
liver
nutrient
oligopyrimidine
preinitiation
rapamycin
refeeding
ribosome
sensing
top
tracts
translation
weights
went
Tagcloud (Intersection)
?