IPO11 and UBE2E2

Number of citations of the paper that reports this interaction (PMID 15545318)
20

Data Source:
BioGRID (pull down)

		IPO11	UBE2E2
Gene Name		importin 11	ubiquitin-conjugating enzyme E2E 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Ran GTPase Binding Protein Transporter Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity ISG15 Transferase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Ribosomal Protein Import Into Nucleus	Cellular Response To DNA Damage Stimulus ISG15-protein Conjugation Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Alcohol and nictotine co-dependence ( 23216389)
Protein-Protein Interactions		11 interactors: C1orf94 EIF4A2 KEAP1 NXF1 PLCD4 RAN RPL12 TRAF2 UBE2E1 UBE2E2 UBE2E3	61 interactors: APP ARIH1 ARIH2 ARRDC3 BARD1 BRCA1 CHFR CUL3 CUL9 DAZAP2 DTX3 DTX3L DZIP3 FAM9B FHL1 IPO11 ISG15 MARCH3 MDM2 MID1 MID2 MKRN3 MUL1 NFE2L2 PCGF2 PRAM1 RING1 RLIM RNF10 RNF103 RNF11 RNF111 RNF114 RNF125 RNF14 RNF166 RNF185 RNF19A RNF2 RNF25 RNF4 RNF5 RNF8 SRPK1 SRPK2 STUB1 TRIM2 TRIM23 TRIM27 TRIM28 TRIM31 TRIM32 TRIM37 TRIM38 TRIM39 TRIM45 TRIM50 UBA1 UBOX5 XIAP ZNRF1
Entrez ID		51194	7325
HPRD ID		10003	06779
Ensembl ID		ENSG00000086200
Uniprot IDs		Q9UI26	Q96LR5
PDB IDs			1Y6L
Enriched GO Terms of Interacting Partners?		Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation ISG15-protein Conjugation Catabolic Process Protein K11-linked Ubiquitination Viral Process Cellular Response To Cytokine Stimulus Response To Cytokine Positive Regulation Of Proteolysis Cellular Macromolecule Catabolic Process Positive Regulation Of Protein Binding Negative Regulation Of RNA-directed RNA Polymerase Activity Cellular Protein Metabolic Process Cytokine-mediated Signaling Pathway Nuclear Export Positive Regulation Of Binding Ribosomal Small Subunit Export From Nucleus Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Ubiquitin-independent Protein Catabolic Process Regulation Of Protein Binding Nuclear-transcribed MRNA Catabolic Process Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process MRNA Catabolic Process Protein Metabolic Process Regulation Of Proteolysis Cytoplasmic Transport RNA Catabolic Process Negative Regulation Of Glial Cell Apoptotic Process Viral Life Cycle Cellular Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Ribosomal Large Subunit Export From Nucleus Histone H2B Ubiquitination Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Ribosomal Subunit Export From Nucleus Poly(A)+ MRNA Export From Nucleus Regulation Of Cell Cycle Phase Transition Translational Initiation Positive Regulation Of Protein Homodimerization Activity Metabolic Process Cellular Response To Nitric Oxide Nucleocytoplasmic Transport Proteasomal Protein Catabolic Process Regulation Of Binding	Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Cellular Protein Metabolic Process Protein Metabolic Process Protein Polyubiquitination Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Metabolic Process Negative Regulation Of Viral Process Protein Autoubiquitination Catabolic Process Regulation Of Viral Process Proteolysis Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Regulation Of Viral Release From Host Cell Metabolic Process Histone Ubiquitination Negative Regulation Of Cellular Metabolic Process Histone H2A Ubiquitination Innate Immune Response Negative Regulation Of Viral Release From Host Cell Protein Monoubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Histone Monoubiquitination Proteasomal Protein Catabolic Process Negative Regulation Of Viral Transcription Response To Stress Regulation Of Protein Ubiquitination Protein K6-linked Ubiquitination Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Immune Response Regulation Of Cell Cycle Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination Cellular Response To Stress Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Defense Response Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Gene Expression
Tagcloud ?			3p24 amino assigned bond cdna conjugating drosophila e1 encoding enzyme extension fluorescence formed hybridization identity kb product shares similarity thioester transcribed transcript ubc ubcd2 ubch6 ubch8 ubcm2 ubiquitin
Tagcloud (Difference) ?			3p24 amino assigned bond cdna conjugating drosophila e1 encoding enzyme extension fluorescence formed hybridization identity kb product shares similarity thioester transcribed transcript ubc ubcd2 ubch6 ubch8 ubcm2 ubiquitin
Tagcloud (Intersection) ?