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IPO11 and RAN
Number of citations of the paper that reports this interaction (PMID
11809816
)
16
Data Source:
HPRD
(in vivo)
IPO11
RAN
Gene Name
importin 11
RAN, member RAS oncogene family
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Chromatin
Nucleus
Nuclear Pore
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Melanosome
Recycling Endosome
Extracellular Vesicular Exosome
Molecular Function
Ran GTPase Binding
Protein Transporter Activity
Chromatin Binding
Transcription Coactivator Activity
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Protein Domain Specific Binding
Poly(A) RNA Binding
Androgen Receptor Binding
Biological Process
Ribosomal Protein Import Into Nucleus
Ribosomal Large Subunit Export From Nucleus
Ribosomal Small Subunit Export From Nucleus
DNA Metabolic Process
Protein Import Into Nucleus
Protein Export From Nucleus
Mitotic Spindle Organization
Mitotic Nuclear Division
Signal Transduction
Small GTPase Mediated Signal Transduction
Spermatid Development
Gene Expression
Viral Process
Viral Life Cycle
Actin Cytoskeleton Organization
Androgen Receptor Signaling Pathway
Positive Regulation Of Protein Binding
Cellular Protein Complex Localization
Small Molecule Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Cell Division
Intracellular Transport Of Virus
Pathways
Transcriptional regulation by small RNAs
Metabolism of lipids and lipoproteins
Nuclear import of Rev protein
HIV Infection
Regulatory RNA pathways
Rev-mediated nuclear export of HIV RNA
Host Interactions of HIV factors
MicroRNA (miRNA) biogenesis
Influenza Infection
Interactions of Rev with host cellular proteins
Late Phase of HIV Life Cycle
Influenza Life Cycle
Regulation of cholesterol biosynthesis by SREBP (SREBF)
Export of Viral Ribonucleoproteins from Nucleus
HIV Life Cycle
Rev-mediated nuclear export of HIV RNA
NEP/NS2 Interacts with the Cellular Export Machinery
Drugs
Diseases
GWAS
Alcohol and nictotine co-dependence (
23216389
)
Protein-Protein Interactions
11 interactors:
C1orf94
EIF4A2
KEAP1
NXF1
PLCD4
RAN
RPL12
TRAF2
UBE2E1
UBE2E2
UBE2E3
55 interactors:
ABL1
ADRB2
AR
ASAP2
BCAR1
BMPR1B
CSE1L
EP300
GADD45G
GIT1
IPO11
IPO13
IPO5
IPO7
KIAA1377
KPNA2
KPNB1
MBP
MSL1
NEK9
NR3C1
NSMF
NUP153
NUP50
NUPR1
NUTF2
NXF1
NXT1
PAK4
PTMA
RANBP1
RANBP10
RANBP2
RANBP3
RANBP9
RANGAP1
RANGRF
RCC1
RGPD5
RPL7
SMAD1
SMAD2
SMARCB1
SMURF2
SNUPN
SPAG8
SSRP1
TGFBR1
TNPO1
TNPO2
XPO1
XPO4
XPO5
XPO7
XPOT
Entrez ID
51194
5901
HPRD ID
10003
03109
Ensembl ID
ENSG00000086200
Uniprot IDs
Q9UI26
B4DV51
P62826
PDB IDs
1I2M
1IBR
1K5D
1K5G
1QBK
1RRP
3CH5
3EA5
3GJ0
3GJ3
3GJ4
3GJ5
3GJ6
3GJ7
3GJ8
3GJX
3NBY
3NBZ
3NC0
3NC1
3ZJY
4GMX
4GPT
4HAT
4HAU
4HAV
4HAW
4HAX
4HAY
4HAZ
4HB0
4HB2
4HB3
4HB4
Enriched GO Terms of Interacting Partners
?
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
ISG15-protein Conjugation
Catabolic Process
Protein K11-linked Ubiquitination
Viral Process
Cellular Response To Cytokine Stimulus
Response To Cytokine
Positive Regulation Of Proteolysis
Cellular Macromolecule Catabolic Process
Positive Regulation Of Protein Binding
Negative Regulation Of RNA-directed RNA Polymerase Activity
Cellular Protein Metabolic Process
Cytokine-mediated Signaling Pathway
Nuclear Export
Positive Regulation Of Binding
Ribosomal Small Subunit Export From Nucleus
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Proteasomal Ubiquitin-independent Protein Catabolic Process
Regulation Of Protein Binding
Nuclear-transcribed MRNA Catabolic Process
Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
MRNA Catabolic Process
Protein Metabolic Process
Regulation Of Proteolysis
Cytoplasmic Transport
RNA Catabolic Process
Negative Regulation Of Glial Cell Apoptotic Process
Viral Life Cycle
Cellular Metabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Ribosomal Large Subunit Export From Nucleus
Histone H2B Ubiquitination
Positive Regulation Of Protein Catabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Ribosomal Subunit Export From Nucleus
Poly(A)+ MRNA Export From Nucleus
Regulation Of Cell Cycle Phase Transition
Translational Initiation
Positive Regulation Of Protein Homodimerization Activity
Metabolic Process
Cellular Response To Nitric Oxide
Nucleocytoplasmic Transport
Proteasomal Protein Catabolic Process
Regulation Of Binding
Nucleocytoplasmic Transport
Nuclear Transport
Cytoplasmic Transport
Intracellular Transport
Protein Transport
Establishment Of Protein Localization
Establishment Of Localization In Cell
Intracellular Protein Transport
Nuclear Import
Protein Localization
Cellular Localization
Protein Localization To Nucleus
Protein Import Into Nucleus
Viral Process
Cellular Protein Localization
Protein Import
Establishment Of Protein Localization To Organelle
RNA Transport
RNA Localization
Protein Localization To Organelle
Protein Targeting
Protein Export From Nucleus
Nuclear Export
Transport
Ribosomal Protein Import Into Nucleus
Positive Regulation Of Ran GTPase Activity
Viral Life Cycle
MRNA Transport
Cellular Response To Organic Substance
Mitotic Cell Cycle
Mitotic Nuclear Envelope Disassembly
Nuclear Envelope Disassembly
NLS-bearing Protein Import Into Nucleus
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Response To Organic Substance
Regulation Of Nucleocytoplasmic Transport
Cell Cycle
Positive Regulation Of Metabolic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Cell Cycle Process
Nuclear Envelope Organization
Mitotic Cell Cycle Process
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Protein Export From Nucleus
Intracellular Transport Of Virus
Regulation Of Intracellular Transport
Cellular Response To Transforming Growth Factor Beta Stimulus
Viral Transcription
Tagcloud
?
5a
accessible
actually
arginine
bandshift
bi
cargo
characterised
directional
dissociated
export
exports
gtpase
heterodimer
import
imported
importin
localisation
masks
multimeric
nes
nls
nucleoplasm
overlaps
rab
rev
rip
shuttle
unspliced
Tagcloud (Difference)
?
5a
accessible
actually
arginine
bandshift
bi
cargo
characterised
directional
dissociated
export
exports
gtpase
heterodimer
import
imported
importin
localisation
masks
multimeric
nes
nls
nucleoplasm
overlaps
rab
rev
rip
shuttle
unspliced
Tagcloud (Intersection)
?