TRIM22 and CASK

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TRIM22	CASK
Gene Name		tripartite motif containing 22	calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Nuclear Speck	Basement Membrane Nuclear Lamina Nucleolus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Actin Cytoskeleton Basolateral Plasma Membrane Nuclear Matrix Presynaptic Membrane Ciliary Membrane
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Zinc Ion Binding Ligase Activity	Guanylate Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding Calmodulin Binding ATP Binding Neurexin Family Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Immune Response Response To Virus Viral Process Protein Ubiquitination Cytokine-mediated Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Protein Trimerization Negative Regulation Of Nucleic Acid-templated Transcription	Negative Regulation Of Cell-matrix Adhesion Protein Phosphorylation Cell Adhesion Negative Regulation Of Keratinocyte Proliferation Extracellular Matrix Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleotide Phosphorylation Negative Regulation Of Wound Healing Calcium Ion Import Positive Regulation Of Calcium Ion Import Negative Regulation Of Cellular Response To Growth Factor Stimulus
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system	Syndecan interactions Nephrin interactions Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CASK CIC CREB1 RERE TAF7 USP7 ZZZ3	60 interactors: APBA1 ATP2B4 BNIP3L C16orf70 CADM1 CASKIN1 CDK9 CNTNAP2 CNTNAP4 DFNB31 DLG1 DLG4 DUSP3 ELL2 EPB41 EPS8 ERBB2IP F11R FCHSD2 GCNT3 GLS2 GRIK2 GRIN2A HGS ID1 IL15RA IL18 KCNA4 KCNJ12 KCNJ2 KCNJ4 LIN7A LIN7B MARS MLLT6 NPHS1 NRXN1 NRXN2 NRXN3 P2RX7 PARK2 PCBP2 PCM1 PLK2 PRKD2 PTGS2 RAB3A RPH3A SDC1 SDC2 SDC3 SDC4 SH2D4A SMEK1 SRPK2 TANC1 TBR1 TRIM22 TSPYL2 WNT7B
Entrez ID		10346	8573
HPRD ID		05951	02164
Ensembl ID		ENSG00000132274	ENSG00000147044
Uniprot IDs		B4DQS5 Q8IYM9	O14936
PDB IDs			1KGD 1KWA 1ZL8 3C0G 3C0H 3C0I 3MFR 3MFS 3MFT 3MFU 3TAC
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Lung Alveolus Development Lactation Transcription, DNA-templated RNA Biosynthetic Process Protein Stabilization Spermine Transport Regulation Of Metabolic Process Body Fluid Secretion Regulation Of Protein Stability RNA Metabolic Process Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Mammary Gland Development Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Maintenance Of DNA Methylation Lung Development Respiratory Tube Development Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription By Competitive Promoter Binding Cellular Metabolic Process Respiratory System Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Keratinocyte Proliferation Lung Saccule Development Positive Regulation Of Calcium Ion Import Multicellular Organismal Development Cellular Response To Zinc Ion Type I Pneumocyte Differentiation Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Intracellular Estrogen Receptor Signaling Pathway Histone Deubiquitination	Synaptic Transmission Signaling Cell Communication Cell-cell Signaling Regulation Of Neurotransmitter Levels Learning Vocalization Behavior Neurotransmitter Secretion Neurotransmitter Transport Single-organism Behavior Learning Or Memory Behavior Cognition Establishment Or Maintenance Of Apical/basal Cell Polarity Cellular Protein Localization Cellular Localization Response To External Stimulus Anatomical Structure Development Social Behavior Cellular Component Assembly Regulation Of Synaptic Transmission System Development Regulation Of Cellular Component Organization Response To Stimulus Synapse Organization Regulation Of Grooming Behavior Regulation Of Organelle Organization Protein Localization To Membrane Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Response To Abiotic Stimulus Multicellular Organismal Development Regulation Of Ion Transport Protein Localization Secretion By Cell Membrane Depolarization Developmental Process Anatomical Structure Morphogenesis Neurological System Process Maintenance Of Apical/basal Cell Polarity Cell Adhesion Membrane Organization Receptor Localization To Synapse Regulation Of Cellular Localization Synapse Assembly Regulation Of Signaling Positive Regulation Of Transport Angiogenesis Regulation Of Intracellular Signal Transduction Secretion Positive Regulation Of Exosomal Secretion
Tagcloud ?		addresses bisulfite blotting breast clonogenic correlates de genotoxic greatly h1299 hypermethylation inducible instead leukemic lines malignant mammary monoclonal motif negatively notion null p53 panel relapse similarly supported tripartite wilms	channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gk gkap guanylate heterologous homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic termed zo
Tagcloud (Difference) ?		addresses bisulfite blotting breast clonogenic correlates de genotoxic greatly h1299 hypermethylation inducible instead leukemic lines malignant mammary monoclonal motif negatively notion null p53 panel relapse similarly supported tripartite wilms	channels clustering coclusters coimmunoprecipitates colocalizes constituent cooh enzymatic fact gk gkap guanylate heterologous homology isolation junction lin maguk nh2 obscure organization pdz postsynaptic psd sap90 sh3 synaptic termed zo
Tagcloud (Intersection) ?