TFG and VPS37C

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TFG	VPS37C
Gene Name		TRK-fused gene	vacuolar protein sorting 37 homolog C (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome	ESCRT I Complex Endosome Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Signal Transducer Activity Protein Binding Identical Protein Binding	Protein Binding Calcium-dependent Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Protein Transport Viral Process Endosomal Transport Viral Life Cycle Virion Assembly Viral Protein Processing Membrane Organization Intracellular Transport Of Virus
Pathways			Assembly Of The HIV Virion Synthesis And Processing Of GAG, GAGPOL Polyproteins HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Membrane binding and targetting of GAG proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		30 interactors: ANXA11 ARHGEF16 ARL15 BOLL C14orf1 CEP55 CRMP1 CSTF2 EWSR1 GBP2 GPRASP1 GRB2 HNRNPF KIAA1377 MAGED1 MAPK1IP1L MED21 MYOT PEF1 PIN1 PLSCR1 PTPN6 RBPMS RIPPLY2 SEC24A SPG21 STAT5B TRIM25 TSSK2 VPS37C	32 interactors: ABI2 AES APP C1orf94 CEP55 DAZAP2 DDIT3 FAM168A GOLGA2 HGS HNRNPUL1 MAPK1IP1L PDCD6 PDCD6IP PKNOX1 PLSCR1 PSMA3 RBPMS RFX6 RINT1 SH3GL1 SORBS2 SORBS3 STAM2 TACC3 TFG TFIP11 TSG101 UBC VPS28 WWP2 XIAP
Entrez ID		10342	55048
HPRD ID		03932	15652
Ensembl ID		ENSG00000114354	ENSG00000167987
Uniprot IDs		Q05BK6 Q92734	A5D8V6
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Cytokine Cytokine-mediated Signaling Pathway Cell Separation After Cytokinesis Response To Interferon-beta JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Growth Hormone Receptor Signaling Pathway Interferon-gamma-mediated Signaling Pathway Cellular Response To Growth Hormone Stimulus Cellular Response To Cytokine Stimulus Regulation Of B Cell Differentiation Immune System Process Cellular Response To Interferon-gamma Defense Response Positive Regulation Of Immune Response Acute-phase Response Response To Growth Hormone Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Interferon-gamma Cellular Response To Organic Substance Mitotic Cytokinesis Negative Regulation Of Type I Interferon Production Platelet Activation JAK-STAT Cascade Positive Regulation Of T Cell Activation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Activation Neurotrophin Signaling Pathway Innate Immune Response Cell Surface Receptor Signaling Pathway Abortive Mitotic Cell Cycle G-protein Coupled Receptor Catabolic Process Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Regulation Of Immune Response Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Cytokinesis, Completion Of Separation Acute Inflammatory Response Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Viral Process Positive Regulation Of Immune System Process T Cell Costimulation Receptor Metabolic Process Cell Cycle Immune Response-activating Cell Surface Receptor Signaling Pathway Response To External Stimulus Regulation Of Body Fluid Levels	Virion Assembly Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Viral Protein Processing Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of ERBB Signaling Pathway Viral Life Cycle Cellular Protein Catabolic Process Endosomal Transport Intracellular Transport Of Virus Protein Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Apoptotic Process Programmed Cell Death Regulation Of Cellular Process Cell Death Regulation Of Extracellular Vesicular Exosome Assembly Death Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Modification-dependent Protein Catabolic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Viral Process Intracellular Transport Cellular Macromolecule Catabolic Process Viral Budding Membrane Organization Gene Expression Positive Regulation Of Exocytosis Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Ubiquitination Cell Cycle Regulation Of Cellular Localization Regulation Of Transcription From RNA Polymerase II Promoter Protein Processing Negative Regulation Of Signal Transduction Establishment Of Protein Localization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Localization Positive Regulation Of Metabolic Process Proteasomal Protein Catabolic Process Cell Separation After Cytokinesis
Tagcloud ?		architecture associate cargo carriers coat coated compartments concentrate copii cup en ergic exit export flexible interface interorganellar laden leave neighboring octameric polymers route slows submicron tight traverse trk uncoating	bl bud budding cargo degrade escrt hairpin hijacks jr k38a multivesicular mvb nl4 p6 polyproteins pppy producer pseudovirus ptap retroviral retrovirus retroviruses tank tbk1 tethering tzm ubiquitylated ultrastructure vero
Tagcloud (Difference) ?		architecture associate carriers coat coated compartments concentrate copii cup en ergic exit export flexible interface interorganellar laden leave neighboring octameric polymers route slows submicron tight traverse trk uncoating	bl bud budding degrade escrt hairpin hijacks jr k38a multivesicular mvb nl4 p6 polyproteins pppy producer pseudovirus ptap retroviral retrovirus retroviruses tank tbk1 tethering tzm ubiquitylated ultrastructure vero
Tagcloud (Intersection) ?		cargo