TFG and METTL27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TFG	METTL27
Description		trafficking from ER to golgi regulator	methyltransferase like 27
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Positive Regulation Of Canonical NF-kappaB Signal Transduction COPII Vesicle Coating
Pathways		COPII-mediated vesicle transport Signaling by ALK fusions and activated point mutants
Drugs
Diseases		Thyroid cancer Non-small cell lung cancer
GWAS		Refractive error ( 32231278)
Interacting Genes		76 interacting genes: ACTMAP ANXA11 ARHGEF16 ARL15 BOLL BPIFA1 CEP126 CEP55 CFTR CRMP1 CRX CSTF2 DAZAP2 DVL3 ERG28 EWSR1 EYA2 FAM168A FOXH1 GBP2 GPRASP1 GRB2 HGS HNRNPF INCA1 INTS11 KHDC1 KRTAP26-1 LASP1 LENG8 MAGED1 MAPK1IP1L MED21 MED25 METTL27 MSS51 MYOT NADSYN1 NID2 OGT OXER1 PEF1 PFDN5 PIN1 PLA2G10 PLEKHG4 PLSCR1 POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PTPN6 RBPMS RIPPLY2 RNF4 SAXO4 SEC24A SF3A2 SF3B4 SMUG1 SNCA SPG21 SPMIP9 STAT5B STH TBX19 TRIM25 TSSK2 UBAP2 UBE2I VPS37C WWOX ZMYM5 ZNF34	29 interacting genes: A1CF ATXN1 ATXN1L CCDC120 CSTF2 DOK6 EFHC1 ENKD1 FOXC2 GLYCTK GPANK1 GRB2 HGS KDM1A LMO4 NOXA1 PITX1 PRKAB2 PRMT6 PROP1 SAXO4 SNRPC TBX6 TEKT3 TFG TLX3 VPS37C ZIC1 ZNF77
Entrez ID		10342	155368
HPRD ID		03932	15661
Ensembl ID		ENSG00000114354	ENSG00000165171
Uniprot IDs		Q05BK6 Q92734	Q8N6F8
PDB IDs		8TEQ 8TER 9E7C
Enriched GO Terms of Interacting Partners?		Protein Binding	POZ Domain Binding Axonemal A Tubule Inner Sheath Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Sequence-specific Double-stranded DNA Binding Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
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