TFG and TSSK2

Number of citations of the paper that reports this interaction (PubMedID 11591653)
29

Data Source:
HPRD (in vivo)

		TFG	TSSK2
Description		trafficking from ER to golgi regulator	testis specific serine kinase 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Endoplasmic Reticulum Exit Site	Acrosomal Vesicle Nucleus Cytoplasm Centriole Cytoskeleton
	Molecular Function	Protein Binding Identical Protein Binding	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein-containing Complex Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Positive Regulation Of Canonical NF-kappaB Signal Transduction COPII Vesicle Coating	Protein Phosphorylation Spermatogenesis Spermatid Development Cell Differentiation Protein Autophosphorylation
Pathways		COPII-mediated vesicle transport Signaling by ALK fusions and activated point mutants
Drugs
Diseases		Thyroid cancer Non-small cell lung cancer
GWAS		Refractive error ( 32231278)	Platelet aggregation ( 29185836)
Interacting Genes		76 interacting genes: ACTMAP ANXA11 ARHGEF16 ARL15 BOLL BPIFA1 CEP126 CEP55 CFTR CRMP1 CRX CSTF2 DAZAP2 DVL3 ERG28 EWSR1 EYA2 FAM168A FOXH1 GBP2 GPRASP1 GRB2 HGS HNRNPF INCA1 INTS11 KHDC1 KRTAP26-1 LASP1 LENG8 MAGED1 MAPK1IP1L MED21 MED25 METTL27 MSS51 MYOT NADSYN1 NID2 OGT OXER1 PEF1 PFDN5 PIN1 PLA2G10 PLEKHG4 PLSCR1 POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PTPN6 RBPMS RIPPLY2 RNF4 SAXO4 SEC24A SF3A2 SF3B4 SMUG1 SNCA SPG21 SPMIP9 STAT5B STH TBX19 TRIM25 TSSK2 UBAP2 UBE2I VPS37C WWOX ZMYM5 ZNF34	8 interacting genes: APP FAM229B LZTS2 PTPRD SKIC2 TFG TSEN15 TSKS
Entrez ID		10342	23617
HPRD ID		03932	10255
Ensembl ID		ENSG00000114354	ENSG00000206203
Uniprot IDs		Q05BK6 Q92734	A0ZT99 Q96PF2
PDB IDs		8TEQ 8TER 9E7C
Enriched GO Terms of Interacting Partners?		Protein Binding	Acetylcholine Receptor Activator Activity Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Postsynapse Organization Lipoprotein Particle Regulation Of Protein Localization To Nucleus Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Developmental Growth Involved In Morphogenesis Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Ski Complex Nuclear-transcribed MRNA Catabolic Process, 3'-5' Exonucleolytic Nonsense-mediated Decay Primary Ureteric Bud Growth Regulation Of Synapse Assembly Regulation Of Spontaneous Synaptic Transmission Negative Regulation Of Wnt Signaling Pathway NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Trans-synaptic Signaling By Trans-synaptic Complex Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway 3'-5' RNA Helicase Activity Ureter Morphogenesis
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