TFG and MYOT

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TFG	MYOT
Gene Name		TRK-fused gene	myotilin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome	Actin Cytoskeleton Z Disc Sarcolemma
	Molecular Function	Signal Transducer Activity Protein Binding Identical Protein Binding	Actin Binding Protein Binding Structural Constituent Of Muscle Alpha-actinin Binding
	Biological Process	Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Muscle Contraction
Pathways
Drugs
Diseases
GWAS			Heart rate ( 23583979)
Protein-Protein Interactions		30 interactors: ANXA11 ARHGEF16 ARL15 BOLL C14orf1 CEP55 CRMP1 CSTF2 EWSR1 GBP2 GPRASP1 GRB2 HNRNPF KIAA1377 MAGED1 MAPK1IP1L MED21 MYOT PEF1 PIN1 PLSCR1 PTPN6 RBPMS RIPPLY2 SEC24A SPG21 STAT5B TRIM25 TSSK2 VPS37C	12 interactors: ACTN1 APP AXIN1 FLNA FLNC GPRASP2 LRP12 NME7 ST7 TFG TRIM55 TRIM63
Entrez ID		10342	9499
HPRD ID		03932	04981
Ensembl ID		ENSG00000114354	ENSG00000120729
Uniprot IDs		Q05BK6 Q92734	B4DT68 Q9UBF9
PDB IDs			2KDG 2KKQ
Enriched GO Terms of Interacting Partners?		Response To Cytokine Cytokine-mediated Signaling Pathway Cell Separation After Cytokinesis Response To Interferon-beta JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Growth Hormone Receptor Signaling Pathway Interferon-gamma-mediated Signaling Pathway Cellular Response To Growth Hormone Stimulus Cellular Response To Cytokine Stimulus Regulation Of B Cell Differentiation Immune System Process Cellular Response To Interferon-gamma Defense Response Positive Regulation Of Immune Response Acute-phase Response Response To Growth Hormone Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Interferon-gamma Cellular Response To Organic Substance Mitotic Cytokinesis Negative Regulation Of Type I Interferon Production Platelet Activation JAK-STAT Cascade Positive Regulation Of T Cell Activation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Activation Neurotrophin Signaling Pathway Innate Immune Response Cell Surface Receptor Signaling Pathway Abortive Mitotic Cell Cycle G-protein Coupled Receptor Catabolic Process Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Regulation Of Immune Response Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Cytokinesis, Completion Of Separation Acute Inflammatory Response Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Viral Process Positive Regulation Of Immune System Process T Cell Costimulation Receptor Metabolic Process Cell Cycle Immune Response-activating Cell Surface Receptor Signaling Pathway Response To External Stimulus Regulation Of Body Fluid Levels	Platelet Degranulation Actin Crosslink Formation Signal Transduction Signaling Platelet Activation Cell Junction Assembly Cell Communication Response To Stimulus Receptor Clustering Vesicle-mediated Transport Microtubule-based Process Cellular Response To Stimulus Exocytosis Wnt-activated Signaling Pathway Involved In Forebrain Neuron Fate Commitment Canonical Wnt Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Blood Coagulation Hemostasis Synaptic Growth At Neuromuscular Junction Cellular Component Assembly Determination Of Left/right Symmetry Establishment Of Localization In Cell Determination Of Bilateral Symmetry Collateral Sprouting In Absence Of Injury Axial Mesoderm Formation Secretion By Cell Microtubule-based Transport Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Localization To Tight Junction Cytoskeleton-dependent Intracellular Transport Regulation Of Body Fluid Levels Neural Plate Anterior/posterior Regionalization Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Collateral Sprouting Axon Midline Choice Point Recognition Wound Healing Regulation Of Growth Transport Secretion Skeletal Muscle Atrophy Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axial Mesoderm Morphogenesis Olfactory Placode Formation Regulation Of Protein Import Into Nucleus Muscle Cell Development Cellular Localization Endocytosis Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Striated Muscle Atrophy Axon Choice Point Recognition Cell Activation
Tagcloud ?		architecture associate cargo carriers coat coated compartments concentrate copii cup en ergic exit export flexible interface interorganellar laden leave neighboring octameric polymers route slows submicron tight traverse trk uncoating	bag3 causative cryab desmin disorganizations dnajb6 encode fhl1 flnc focal hereditary hmerf hyaline inclusions mfm muscles myofibril myofibrillar myopathy name pathologically pathomechanisms quite spheroid summarized ttn unexpectedly vcp zasp
Tagcloud (Difference) ?		architecture associate cargo carriers coat coated compartments concentrate copii cup en ergic exit export flexible interface interorganellar laden leave neighboring octameric polymers route slows submicron tight traverse trk uncoating	bag3 causative cryab desmin disorganizations dnajb6 encode fhl1 flnc focal hereditary hmerf hyaline inclusions mfm muscles myofibril myofibrillar myopathy name pathologically pathomechanisms quite spheroid summarized ttn unexpectedly vcp zasp
Tagcloud (Intersection) ?