TFG and SEC24A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TFG	SEC24A
Description		trafficking from ER to golgi regulator	SEC24 homolog A, COPII component
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Endoplasmic Reticulum Exit Site	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Membrane COPII Vesicle Coat Cytoplasmic Vesicle Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Identical Protein Binding	SNARE Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Positive Regulation Of Canonical NF-kappaB Signal Transduction COPII Vesicle Coating	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport Regulation Of Cholesterol Transport Cholesterol Homeostasis Positive Regulation Of Protein Secretion COPII-coated Vesicle Cargo Loading
Pathways		COPII-mediated vesicle transport Signaling by ALK fusions and activated point mutants	Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER SARS-CoV-2 activates/modulates innate and adaptive immune responses Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases		Thyroid cancer Non-small cell lung cancer
GWAS		Refractive error ( 32231278)
Interacting Genes		76 interacting genes: ACTMAP ANXA11 ARHGEF16 ARL15 BOLL BPIFA1 CEP126 CEP55 CFTR CRMP1 CRX CSTF2 DAZAP2 DVL3 ERG28 EWSR1 EYA2 FAM168A FOXH1 GBP2 GPRASP1 GRB2 HGS HNRNPF INCA1 INTS11 KHDC1 KRTAP26-1 LASP1 LENG8 MAGED1 MAPK1IP1L MED21 MED25 METTL27 MSS51 MYOT NADSYN1 NID2 OGT OXER1 PEF1 PFDN5 PIN1 PLA2G10 PLEKHG4 PLSCR1 POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PTPN6 RBPMS RIPPLY2 RNF4 SAXO4 SEC24A SF3A2 SF3B4 SMUG1 SNCA SPG21 SPMIP9 STAT5B STH TBX19 TRIM25 TSSK2 UBAP2 UBE2I VPS37C WWOX ZMYM5 ZNF34	7 interacting genes: ARID5A CBFA2T3 EWSR1 PEF1 TFG TRIP13 USP54
Entrez ID		10342	10802
HPRD ID		03932	08456
Ensembl ID		ENSG00000114354	ENSG00000113615
Uniprot IDs		Q05BK6 Q92734	B4E205 O95486
PDB IDs		8TEQ 8TER 9E7C	2NUP 2NUT 3EGD 3EGX 5VNE 5VNF 5VNG 5VNH 5VNI 5VNJ 5VNK 5VNL 5VNM 5VNN 5VNO 8HR0
Enriched GO Terms of Interacting Partners?		Protein Binding	COPII Vesicle Coating Vesicle Coating
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