TFG and NADSYN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TFG	NADSYN1
Description		trafficking from ER to golgi regulator	NAD synthetase 1
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Endoplasmic Reticulum Exit Site	Cytoplasm Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	Nucleotide Binding NAD+ Synthase (glutamine-hydrolyzing) Activity Glutaminase Activity Protein Binding ATP Binding Ligase Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Positive Regulation Of Canonical NF-kappaB Signal Transduction COPII Vesicle Coating	NAD+ Biosynthetic Process 'de Novo' NAD+ Biosynthetic Process From L-tryptophan NAD+ Biosynthetic Process Via The Salvage Pathway
Pathways		COPII-mediated vesicle transport Signaling by ALK fusions and activated point mutants	Nicotinate metabolism
Drugs			Glutamic acid
Diseases		Thyroid cancer Non-small cell lung cancer
GWAS		Refractive error ( 32231278)	Systemic lupus erythematosus ( 26502338) Vitamin D insufficiency ( 20541252) Vitamin D levels ( 20418485 29343764) Vitamin D levels (dietary vitamin D intake interaction) ( 29343764)
Interacting Genes		76 interacting genes: ACTMAP ANXA11 ARHGEF16 ARL15 BOLL BPIFA1 CEP126 CEP55 CFTR CRMP1 CRX CSTF2 DAZAP2 DVL3 ERG28 EWSR1 EYA2 FAM168A FOXH1 GBP2 GPRASP1 GRB2 HGS HNRNPF INCA1 INTS11 KHDC1 KRTAP26-1 LASP1 LENG8 MAGED1 MAPK1IP1L MED21 MED25 METTL27 MSS51 MYOT NADSYN1 NID2 OGT OXER1 PEF1 PFDN5 PIN1 PLA2G10 PLEKHG4 PLSCR1 POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PTPN6 RBPMS RIPPLY2 RNF4 SAXO4 SEC24A SF3A2 SF3B4 SMUG1 SNCA SPG21 SPMIP9 STAT5B STH TBX19 TRIM25 TSSK2 UBAP2 UBE2I VPS37C WWOX ZMYM5 ZNF34	13 interacting genes: ANKS1A COL8A1 CREB5 CUTC FRS3 GPANK1 HGS HOXC8 MYO15B NOXA1 NTAQ1 TFG UPF1
Entrez ID		10342	55191
HPRD ID		03932	16309
Ensembl ID		ENSG00000114354	ENSG00000172890
Uniprot IDs		Q05BK6 Q92734	Q6IA69
PDB IDs		8TEQ 8TER 9E7C	6OFB
Enriched GO Terms of Interacting Partners?		Protein Binding
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