TFG and ZNF34

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TFG	ZNF34
Description		trafficking from ER to golgi regulator	zinc finger protein 34
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Endoplasmic Reticulum Exit Site	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Positive Regulation Of Canonical NF-kappaB Signal Transduction COPII Vesicle Coating	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		COPII-mediated vesicle transport Signaling by ALK fusions and activated point mutants	Generic Transcription Pathway
Drugs
Diseases		Thyroid cancer Non-small cell lung cancer
GWAS		Refractive error ( 32231278)	Blood metabolite levels ( 26401656) Logical memory (immediate recall) in normal cognition ( 29274321) Type 2 diabetes ( 30054458)
Interacting Genes		76 interacting genes: ACTMAP ANXA11 ARHGEF16 ARL15 BOLL BPIFA1 CEP126 CEP55 CFTR CRMP1 CRX CSTF2 DAZAP2 DVL3 ERG28 EWSR1 EYA2 FAM168A FOXH1 GBP2 GPRASP1 GRB2 HGS HNRNPF INCA1 INTS11 KHDC1 KRTAP26-1 LASP1 LENG8 MAGED1 MAPK1IP1L MED21 MED25 METTL27 MSS51 MYOT NADSYN1 NID2 OGT OXER1 PEF1 PFDN5 PIN1 PLA2G10 PLEKHG4 PLSCR1 POU2AF1 PRR20A PRR20B PRR20C PRR20D PRR20E PTPN6 RBPMS RIPPLY2 RNF4 SAXO4 SEC24A SF3A2 SF3B4 SMUG1 SNCA SPG21 SPMIP9 STAT5B STH TBX19 TRIM25 TSSK2 UBAP2 UBE2I VPS37C WWOX ZMYM5 ZNF34	44 interacting genes: ANKHD1 CYSRT1 DAZAP2 DTX2 FOXH1 GCM2 HGS HOXC8 KRTAP10-5 KRTAP26-1 KRTAP8-1 LENG8 LMO2 MAPKBP1 MKRN3 NFYC OTX1 PITX1 PITX2 PLSCR4 POU6F2 RBPMS RBPMS2 ROR2 RSPH1 RUSC1 SPAG8 TBX3 TBX6 TCF7L2 TFG TIAM1 TLE5 TLX3 TRIP13 UBAP2 VAC14 VENTX VGLL3 VPS37C WDR25 YTHDF1 ZC3H10 ZIC1
Entrez ID		10342	80778
HPRD ID		03932	11772
Ensembl ID		ENSG00000114354	ENSG00000196378
Uniprot IDs		Q05BK6 Q92734	A0A0C4DG42 E9PNZ6 Q8IZ26
PDB IDs		8TEQ 8TER 9E7C
Enriched GO Terms of Interacting Partners?		Protein Binding	DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Nucleus Sequence-specific Double-stranded DNA Binding Chromatin Regulation Of RNA Metabolic Process Regulation Of Gene Expression Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Myoblast Fate Commitment Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Embryonic Hindlimb Morphogenesis Pattern Specification Process Embryonic Morphogenesis Hindlimb Morphogenesis Cytoplasmic Stress Granule Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Transcription Regulator Complex Positive Regulation Of Macromolecule Metabolic Process Inner Ear Morphogenesis DNA Binding Outflow Tract Morphogenesis Wnt Signaling Pathway Regionalization Mitogen-activated Protein Kinase Kinase Kinase Binding Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Metabolic Process Negative Regulation Of Androgen Receptor Signaling Pathway Embryonic Digestive Tract Morphogenesis Axis Specification Sequence-specific DNA Binding DNA-binding Transcription Factor Binding Identical Protein Binding Cell Fate Specification Positive Regulation Of Metabolic Process Embryonic Limb Morphogenesis
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