- and MESD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		-	MESD
Description		salt inducible kinase 1B (putative)	mesoderm development LRP chaperone
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Endoplasmic Reticulum Plasma Membrane
	Molecular Function		Protein Binding Identical Protein Binding Protein Folding Chaperone Low-density Lipoprotein Particle Receptor Binding
	Biological Process		Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Protein Localization To Cell Surface Protein Localization To Plasma Membrane Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways		Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes
Drugs		Dabrafenib Fostamatinib
Diseases
GWAS		HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		6 interacting genes: GINS4 LHX8 MESD PITX1 PRTFDC1 TIMM10	78 interacting genes: - ABCG8 ABITRAM ACBD7 AKIRIN2 AKNAD1 AKT1 APP ARB2A ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KLHL20 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MAPDA MCM9 MELTF MKNK2 MRM1 MTNR1A NAA35 NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SLC6A20 SMARCB1 SNX5 SNX7 TEKTL1 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844
Entrez ID		102724428	23184
HPRD ID			12129
Ensembl ID		ENSG00000275993	ENSG00000117899
Uniprot IDs		P57059	Q14696
PDB IDs
Enriched GO Terms of Interacting Partners?		Branchiomeric Skeletal Muscle Development Myoblast Fate Commitment Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Receptor Clustering TIM22 Mitochondrial Import Inner Membrane Insertion Complex Mitochondrial Intermembrane Space Chaperone Complex Purine Nucleoside Monophosphate Catabolic Process Purine Ribonucleoside Salvage Hypoxanthine Phosphoribosyltransferase Activity Nucleoside Salvage Guanine Salvage Guanine Metabolic Process GMP Catabolic Process Purine Nucleobase Biosynthetic Process CMG Complex Double-strand Break Repair Via Break-induced Replication GINS Complex	Protein Binding Proton-transporting Two-sector ATPase Complex, Catalytic Domain
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