- and TIMM10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		-	TIMM10
Description		salt inducible kinase 1B (putative)	translocase of inner mitochondrial membrane 10
Image		No pdb structure
GO Annotations	Cellular Component		Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Intermembrane Space Membrane Mitochondrial Intermembrane Space Chaperone Complex TIM22 Mitochondrial Import Inner Membrane Insertion Complex
	Molecular Function		Protein Binding Zinc Ion Binding Membrane Insertase Activity Protein Homodimerization Activity Metal Ion Binding Protein-folding Chaperone Binding
	Biological Process		Protein Targeting To Mitochondrion Sensory Perception Of Sound Protein Transport Protein Insertion Into Mitochondrial Inner Membrane
Pathways		Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes	Mitochondrial protein import Mitochondrial protein import Mitochondrial protein degradation
Drugs		Dabrafenib Fostamatinib
Diseases
GWAS		HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)	Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		6 interacting genes: GINS4 LHX8 MESD PITX1 PRTFDC1 TIMM10	3 interacting genes: - TBC1D21 ZNF655
Entrez ID		102724428	26519
HPRD ID			03768
Ensembl ID		ENSG00000275993	ENSG00000134809
Uniprot IDs		P57059	P62072
PDB IDs			2BSK 7CGP
Enriched GO Terms of Interacting Partners?		Branchiomeric Skeletal Muscle Development Myoblast Fate Commitment Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Receptor Clustering TIM22 Mitochondrial Import Inner Membrane Insertion Complex Mitochondrial Intermembrane Space Chaperone Complex Purine Nucleoside Monophosphate Catabolic Process Purine Ribonucleoside Salvage Hypoxanthine Phosphoribosyltransferase Activity Nucleoside Salvage Guanine Salvage Guanine Metabolic Process GMP Catabolic Process Purine Nucleobase Biosynthetic Process CMG Complex Double-strand Break Repair Via Break-induced Replication GINS Complex	Aldehyde Metabolic Process Positive Regulation Of Deacetylase Activity Glycerone Kinase Activity Triokinase Activity FAD-AMP Lyase (cyclizing) Activity Retrograde Trans-synaptic Signaling By Endocannabinoid Monoacylglycerol Biosynthetic Process Cannabinoid Biosynthetic Process Diacylglycerol Catabolic Process Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Retinal Cell Programmed Cell Death Ciliary Neurotrophic Factor Receptor Binding Interleukin-6 Receptor Binding Ciliary Neurotrophic Factor-mediated Signaling Pathway Hydroxyacylglutathione Hydrolase Activity Methylglyoxal Metabolic Process Methylglyoxal Catabolic Process To Lactate Cellular Detoxification Of Methylglyoxal Methylglyoxal Catabolic Process To D-lactate Via S-lactoyl-glutathione CCR1 Chemokine Receptor Binding Release From Viral Latency Glycerol Catabolic Process Fructose Catabolic Process Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate Negative Regulation Of MDA-5 Signaling Pathway Sperm Mitochondrial Sheath Assembly Varicosity Muscle Organ Morphogenesis Lipoprotein Lipase Activity Positive Regulation Of Axon Regeneration Retinal Rod Cell Differentiation CAMP Response Element Binding Protein Binding Plasma Membrane To Endosome Transport Monoacylglycerol Lipase Activity Glyceraldehyde-3-phosphate Metabolic Process
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