EFS and SORBS2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EFS	SORBS2
Gene Name		embryonal Fyn-associated substrate	sorbin and SH3 domain containing 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Plasma Membrane Actin Cytoskeleton Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	SH3 Domain Binding Protein Domain Specific Binding	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Structural Constituent Of Muscle Protein Domain Specific Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Cell Adhesion Intracellular Signal Transduction	Actin Filament Organization Cell Adhesion Biological_process Cell Migration
Pathways
Drugs
Diseases
GWAS			Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		21 interactors: ABI2 APP BCAR1 BLK CRK FYN LYST NPAS2 NUP155 OSTF1 PTK2 PTK2B PTPN12 SH2D3C SORBS2 SORBS3 SRC TRAPPC6A TSSK1B UBC ZNF417	35 interactors: ABL1 ABL2 ACTN1 ADAM15 AKT1 AKT2 ATPAF2 CBL DLGAP1 DLGAP2 DLGAP4 EFS EGFR FLOT1 MDM2 MLLT4 NCK2 NR1H2 PAK1 PAK2 PALLD PKM PTK2B PTPN12 RPL9 SEMA6A SH2D4A SYNJ1 TRAF4 VCL VPS37C WAS WASF1 YWHAE YWHAZ
Entrez ID		10278	8470
HPRD ID		09932	12473
Ensembl ID		ENSG00000100842	ENSG00000154556
Uniprot IDs		B4DJ56 O43281	B7Z3D7 B7Z997 O94875
PDB IDs			4IGZ
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Autophosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Innate Immune Response Platelet Activation Immune Response-regulating Cell Surface Receptor Signaling Pathway Signal Complex Assembly Positive Regulation Of Immune System Process Blood Coagulation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Hemostasis Cell Activation Peptidyl-tyrosine Phosphorylation Immune Response-regulating Signaling Pathway Actin Filament Organization Cellular Response To Peptide Hormone Stimulus Cell Migration Cellular Response To Peptide Locomotion Regulation Of Body Fluid Levels Cell Motility Enzyme Linked Receptor Protein Signaling Pathway Wound Healing Protein Autophosphorylation Immune Response Regulation Of Immune System Process Positive Regulation Of Immune Response Defense Response Phosphate-containing Compound Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Phosphorylation Neurotrophin Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase Activity Response To Wounding Ephrin Receptor Signaling Pathway Response To Peptide Hormone Movement Of Cell Or Subcellular Component Cellular Response To Organonitrogen Compound Response To Peptide Fc Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Cell Adhesion Response To Organonitrogen Compound Integrin-mediated Signaling Pathway Immune System Process Positive Regulation Of Signal Transduction Regulation Of Immune Response Antigen Receptor-mediated Signaling Pathway	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Component Movement Signaling Positive Regulation Of Transport Cell Communication Positive Regulation Of Organelle Organization Programmed Cell Death Regulation Of Cell Motility Cell Death Death Protein Autophosphorylation Regulation Of Cellular Component Organization Cell Activation Regulation Of Locomotion Regulation Of Cellular Ketone Metabolic Process Regulation Of Organelle Organization Positive Regulation Of Intracellular Transport Regulation Of Signaling Axonogenesis Cell Morphogenesis Involved In Differentiation Regulation Of Catalytic Activity Cellular Localization Regulation Of Signal Transduction Apoptotic Process Regulation Of Oxidoreductase Activity Cell Development Axon Development Positive Regulation Of Signal Transduction Fc Receptor Signaling Pathway Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cellular Localization Regulation Of Intracellular Transport Neuron Projection Development Innate Immune Response Actin Filament Organization Neuron Projection Morphogenesis Neurogenesis Positive Regulation Of Oxidoreductase Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization Cell Projection Organization Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Cell Adhesion Movement Of Cell Or Subcellular Component Neuron Development Regulation Of Actin Cytoskeleton Organization
Tagcloud ?		alg aplastic austria beginning bmt cessation cr csa cured cyclosporin evaluable germany immunosuppressive ist mentioned microliter nonresponders pmn probability pts relapsed relapses resp saa sibling suffered tapering transfusions vsaa
Tagcloud (Difference) ?		alg aplastic austria beginning bmt cessation cr csa cured cyclosporin evaluable germany immunosuppressive ist mentioned microliter nonresponders pmn probability pts relapsed relapses resp saa sibling suffered tapering transfusions vsaa
Tagcloud (Intersection) ?