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DPP3 and TERF2IP
Number of citations of the paper that reports this interaction (PMID
21044950
)
9
Data Source:
BioGRID
(two hybrid)
DPP3
TERF2IP
Gene Name
dipeptidyl-peptidase 3
telomeric repeat binding factor 2, interacting protein
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Plasma Membrane
Extracellular Vesicular Exosome
Nuclear Chromosome
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nuclear Chromosome, Telomeric Region
Nucleus
Nuclear Envelope
Nucleoplasm
Cytoplasm
Mre11 Complex
Molecular Function
Protein Binding
Metallopeptidase Activity
Dipeptidyl-peptidase Activity
Zinc Ion Binding
Protein Binding
Telomeric DNA Binding
Biological Process
Proteolysis
Telomere Maintenance
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Telomere Maintenance Via Telomerase
Regulation Of Double-strand Break Repair Via Homologous Recombination
Telomere Maintenance Via Telomere Lengthening
Protection From Non-homologous End Joining At Telomere
Negative Regulation Of Telomere Maintenance
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of DNA Recombination At Telomere
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Localization To Chromosome, Telomeric Region
Pathways
Telomere Maintenance
Packaging Of Telomere Ends
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
Cellular Senescence
Meiotic synapsis
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Protein-Protein Interactions
9 interactors:
APP
ATP5C1
HSPA8
KEAP1
LIG4
POT1
TERF1
TERF2IP
TINF2
125 interactors:
ADA
AIMP2
AK1
AKR1A1
AKR1B10
AKR7A3
AKT1
ANXA5
AP2B1
APEX1
ARPP21
BABAM1
BANP
BCL7B
C1orf174
C9orf78
CALML3
CHMP2B
COTL1
CPNE2
CPNE3
CRK
CRYBB1
CRYGS
CTBP1
DBNL
DDX23
DDX24
DDX39A
DHX38
DNMT3A
DPP3
ENAH
EPAS1
EPS8L1
FABP2
FAM122A
GAGE5
GAMT
GNMT
GPKOW
HAAO
HAGH
HDGFRP3
HIST1H1A
HIST1H2AL
HIST1H4B
HMGB1
HMGB3
HMGN3
HMGN4
HNRNPK
IDO1
IL1RN
LANCL2
LGALSL
MAGOHB
MCM2
MDH1
MPG
MRTO4
MT1X
MT3
NAIF1
NASP
NOL3
NUDT14
NUDT18
NUMA1
NXNL1
OCM2
OGFR
PACSIN2
PACSIN3
PAFAH1B3
PCNP
PCP4
PEA15
PGLS
PGM1
PML
PNMT
POLD1
PPM1G
PPP1R2
PPP6R3
PRDX6
PRX
PTMA
RABIF
RAD50
RASSF5
RBBP9
RECQL4
RGMA
RIF1
RPAP1
RPP25
S100P
SBDS
SCLY
SCRN2
SET
SMARCC2
SNCG
SP100
TALDO1
TBC1D10A
TBCA
TERF2
TMSB10
TMSB4Y
TOR1AIP1
TSSC4
TWF2
UCHL1
VGLL4
WDR5
WIPI2
XAGE2
XPO1
XRCC5
XRCC6
ZNF146
ZNF414
Entrez ID
10072
54386
HPRD ID
06012
05452
Ensembl ID
ENSG00000254986
ENSG00000166848
Uniprot IDs
Q5JPB8
Q9NY33
Q9NYB0
PDB IDs
3FVY
3T6B
3T6J
1FEX
3K6G
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Telomere Maintenance Via Telomerase
Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomerase
Telomere Maintenance
Negative Regulation Of Chromosome Organization
Negative Regulation Of DNA Metabolic Process
RNA-dependent DNA Replication
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of DNA Replication
Regulation Of Chromosome Organization
Cellular Nitrogen Compound Metabolic Process
Protein Localization To Chromosome, Telomeric Region
Telomere Capping
Nitrogen Compound Metabolic Process
DNA Replication
Telomere Assembly
Negative Regulation Of Telomerase Activity
Positive Regulation Of Telomere Maintenance
Regulation Of DNA Replication
Regulation Of Telomerase Activity
Chromosome Organization
DNA Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of DNA Biosynthetic Process
Protein Localization To Chromosome
Homeostatic Process
Regulation Of DNA Biosynthetic Process
Neuron Apoptotic Process
Regulation Of Organelle Organization
Neuron Death
Regulation Of Cellular Component Organization
Biosynthetic Process
Positive Regulation Of Organelle Organization
Negative Regulation Of Protein ADP-ribosylation
DNA Ligation Involved In DNA Recombination
Negative Regulation Of Fibril Organization
Positive Regulation Of DNA Strand Elongation
Negative Regulation Of DNA Recombination At Telomere
Regulation Of Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Protein ADP-ribosylation
Synaptic Growth At Neuromuscular Junction
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Chromosome Organization
Telomere Maintenance
Cellular Nitrogen Compound Metabolic Process
Organelle Organization
Nitrogen Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Chromatin Organization
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
DNA Conformation Change
Chromatin Modification
Cell Cycle
Cellular Response To Stress
DNA Metabolic Process
Cellular Response To DNA Damage Stimulus
Sequestering Of Actin Monomers
DNA Recombination
Telomere Maintenance Via Telomere Lengthening
Catabolic Process
DNA Duplex Unwinding
Cellular Aldehyde Metabolic Process
Cellular Hyperosmotic Salinity Response
DNA Geometric Change
DNA Replication
Energy Reserve Metabolic Process
Nucleosome Organization
Organophosphate Catabolic Process
Response To Stress
Chromatin Assembly Or Disassembly
Deoxyribose Phosphate Catabolic Process
Cellular Localization
Cellular Metabolic Process
Protein Localization To Nucleus
Glycogen Metabolic Process
Nucleocytoplasmic Transport
Chromatin Remodeling
Base-excision Repair
Cellular Response To X-ray
Nuclear Transport
Aromatic Compound Catabolic Process
Nucleosome Assembly
Deoxyribonucleotide Catabolic Process
DNA Strand Elongation Involved In DNA Replication
Small Molecule Metabolic Process
DNA Strand Elongation
Biosynthetic Process
Chromatin Assembly
Regulation Of Cysteine-type Endopeptidase Activity
Negative Regulation Of Transport
Energy Derivation By Oxidation Of Organic Compounds
Tagcloud
?
acd
add
broader
clustered
clustering
convincingly
correction
cosegregated
ends
families
fisher
germline
inactivating
lod
logarithm
melanoma
nonsense
pot1
predispose
probands
q320x
r364x
shelterin
tailed
terf1
tinf
tinf2
yates
Tagcloud (Difference)
?
acd
add
broader
clustered
clustering
convincingly
correction
cosegregated
ends
families
fisher
germline
inactivating
lod
logarithm
melanoma
nonsense
pot1
predispose
probands
q320x
r364x
shelterin
tailed
terf1
tinf
tinf2
yates
Tagcloud (Intersection)
?