ABI1 and WASF1

Number of citations of the paper that reports this interaction (PMID 15048123)
103

Data Source:
HPRD (in vitro)

		ABI1	WASF1
Gene Name		abl-interactor 1	WAS protein family, member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Endoplasmic Reticulum Cytosol Cytoskeleton Postsynaptic Density Lamellipodium Cell Junction Filopodium Growth Cone SCAR Complex Postsynaptic Membrane Extracellular Vesicular Exosome	Cytoskeleton Actin Cytoskeleton Cell Junction SCAR Complex Synapse
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Protein Tyrosine Kinase Activator Activity Protein Complex Binding	Actin Binding Protein Binding Protein Complex Binding Rac GTPase Binding
	Biological Process	Somitogenesis Movement Of Cell Or Subcellular Component Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Actin Polymerization Or Depolymerization Negative Regulation Of Cell Proliferation Peptidyl-tyrosine Phosphorylation Megakaryocyte Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Tyrosine Kinase Activity Lamellipodium Morphogenesis	Protein Complex Assembly Movement Of Cell Or Subcellular Component Rac Protein Signal Transduction Actin Filament Polymerization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System	Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ABL1 APBB1 CACNA1A CYFIP2 ENAH EPS8 EPS8L1 EVL GAS7 HSPA8 MINK1 NCK1 NCK2 NCKAP1 NEB NIN PAK2 PRPF40A SOS1 SOS2 SPTA1 SPTAN1 SRRM1 TCERG1 VASP WASF1 WASF2	28 interactors: ABI1 ABL1 ACTB ACTG1 ACTR2 BAD BAIAP2 BRK1 CDC42 CDK5 CRK CXCL8 CYFIP2 DNMBP FYN GNAI1 GRB2 IFT20 IL12A NCK1 NCKAP1 PFN1 PRKAR2A PSTPIP1 RAC1 SORBS2 SRGAP3 TRIP10
Entrez ID		10006	8936
HPRD ID		04336	05434
Ensembl ID		ENSG00000136754	ENSG00000112290
Uniprot IDs		B6VEX3 B6VEX4 B6VEX5 Q8IZP0	Q92558
PDB IDs			3P8C
Enriched GO Terms of Interacting Partners?		Neuron Projection Morphogenesis Cell Projection Morphogenesis Cell Part Morphogenesis Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Movement Of Cell Or Subcellular Component Neuron Projection Development Cell Morphogenesis Axon Guidance Cell Morphogenesis Involved In Differentiation Neuron Development Locomotion Actin Filament-based Process Regulation Of Actin Cytoskeleton Organization Axonogenesis Neuron Differentiation Regulation Of Actin Filament-based Process Axon Development Actin Cytoskeleton Organization Chemotaxis Regulation Of Cellular Component Organization Regulation Of Cytoskeleton Organization Cytoskeleton Organization Cell Development Actin Filament Organization Generation Of Neurons Neurogenesis Anatomical Structure Morphogenesis Nervous System Development Regulation Of Actin Filament Length Regulation Of Organelle Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Actin Filament Polymerization Immune Response-regulating Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To External Stimulus Regulation Of Cellular Component Size Regulation Of Actin Polymerization Or Depolymerization System Development Rac Protein Signal Transduction Cell Differentiation Fc Receptor Signaling Pathway Multicellular Organismal Development Organelle Organization Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Actin Polymerization Or Depolymerization Anatomical Structure Development	Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Fc Receptor Signaling Pathway Endocytosis Phagocytosis Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Vesicle-mediated Transport Innate Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Immune Response Defense Response Positive Regulation Of Immune System Process Positive Regulation Of Immune Response Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Immune System Process Actin Cytoskeleton Organization Actin Filament-based Process Immune System Process Response To Stress Signaling Blood Coagulation Cell Communication Hemostasis Movement Of Cell Or Subcellular Component Signal Transduction Regulation Of Actin Cytoskeleton Organization Regulation Of Cytoskeleton Organization Cell Surface Receptor Signaling Pathway Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Transport Cellular Response To Stimulus Regulation Of Body Fluid Levels Locomotion Wound Healing Cell Projection Morphogenesis Cell Part Morphogenesis Cytoskeleton Organization Cell Projection Organization Response To Stimulus Response To Wounding Axonogenesis Axon Guidance Ephrin Receptor Signaling Pathway Axon Development
Tagcloud ?		aba abl1 abscisic advantage arabidopsis assayed character contrary copies defense dormancy drought implicates lap le25 meja mrnas pin2 proteinase requisite seed signalling tas14 tomato transcripts transformants wilty wound wounding
Tagcloud (Difference) ?		aba abl1 abscisic advantage arabidopsis assayed character contrary copies defense dormancy drought implicates lap le25 meja mrnas pin2 proteinase requisite seed signalling tas14 tomato transcripts transformants wilty wound wounding
Tagcloud (Intersection) ?