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WASF1
Description
WASP family member 1
Image
GO Annotations
Cellular Component
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Cytosol
Cytoskeleton
Focal Adhesion
Actin Cytoskeleton
Lamellipodium
SCAR Complex
Dendrite Cytoplasm
Protein-containing Complex
Synapse
Anchoring Junction
Postsynapse
Molecular Function
Actin Binding
Protein Binding
Small GTPase Binding
Protein Kinase A Regulatory Subunit Binding
Protein Kinase A Binding
Arp2/3 Complex Binding
Biological Process
Receptor-mediated Endocytosis
Mitochondrion Organization
Rac Protein Signal Transduction
Actin Cytoskeleton Organization
Actin Filament Polymerization
Neuron Projection Development
Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Protein-containing Complex Assembly
Lamellipodium Morphogenesis
Dendrite Extension
Modification Of Postsynaptic Actin Cytoskeleton
Dendritic Transport Of Mitochondrion
Cellular Response To Brain-derived Neurotrophic Factor Stimulus
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
RAC1 GTPase cycle
RAC3 GTPase cycle
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Novel Interacting Genes
1 novel interacting genes:
MMS22L
Interacting Genes
38 interacting genes:
ABI1
ABI3
ABL1
ACTB
ACTG1
ACTR2
BAD
BRK1
CCDC196
CDC42
CDK5
CRK
CXCL8
CYFIP2
DNMBP
EFHC1
FYN
GNAI1
GRB2
HSF2BP
IFT20
IL12A
ING5
LMO2
MAPKAPK2
NCK1
NCK2
NCKAP1
NYAP2
OSTF1
PFN1
PRKAR2A
PSTPIP1
RAC1
SORBS2
SRGAP3
TRAF2
TRIP10
Entrez ID
8936
HPRD ID
05434
Ensembl ID
ENSG00000112290
Uniprot IDs
Q92558
PDB IDs
3P8C
4N78
7USC
7USD
7USE
Enriched GO Terms of Interacting Partners
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Actin Cytoskeleton Organization
Actin Filament-based Process
Cell Motility
Cell Projection Organization
Regulation Of Actin Cytoskeleton Organization
Regulation Of Actin Filament Organization
SCAR Complex
Regulation Of Actin Filament-based Process
Regulation Of Cytoskeleton Organization
Positive Regulation Of Supramolecular Fiber Organization
Cytoskeleton Organization
Regulation Of Cellular Component Organization
Regulation Of Organelle Organization
Regulation Of Lamellipodium Assembly
Positive Regulation Of Cytoskeleton Organization
Lamellipodium
Cell Migration
Cell Projection Morphogenesis
Regulation Of Supramolecular Fiber Organization
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Positive Regulation Of Actin Filament Polymerization
Regulation Of Cell Projection Organization
Regulation Of Lamellipodium Organization
Regulation Of Protein-containing Complex Assembly
Plasma Membrane Bounded Cell Projection Organization
Positive Regulation Of Lamellipodium Assembly
Ephrin Receptor Binding
Positive Regulation Of Cell Projection Organization
Cell Projection Assembly
Neuron Projection Morphogenesis
Signal Transduction
Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly
Positive Regulation Of Cell Adhesion
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament Polymerization
Positive Regulation Of Cellular Component Biogenesis
Regulation Of Cell Adhesion
Positive Regulation Of Lamellipodium Organization
Signaling Adaptor Activity
Positive Regulation Of Protein Polymerization
Regulation Of Cell Projection Assembly
Lamellipodium Organization
Establishment Or Maintenance Of Cell Polarity
Phosphotyrosine Residue Binding
Plasma Membrane Bounded Cell Projection Assembly
Regulation Of Cellular Component Size
Organelle Organization
Ephrin Receptor Signaling Pathway
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