ABI1 and NIN

Number of citations of the paper that reports this interaction (PMID 15048123)
103

Data Source:
HPRD (in vitro)

		ABI1	NIN
Gene Name		abl-interactor 1	ninein (GSK3B interacting protein)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Endoplasmic Reticulum Cytosol Cytoskeleton Postsynaptic Density Lamellipodium Cell Junction Filopodium Growth Cone SCAR Complex Postsynaptic Membrane Extracellular Vesicular Exosome	Spindle Pole Nucleolus Centrosome Centriole Microtubule
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Protein Tyrosine Kinase Activator Activity Protein Complex Binding	Calcium Ion Binding Protein Binding GTP Binding
	Biological Process	Somitogenesis Movement Of Cell Or Subcellular Component Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Actin Polymerization Or Depolymerization Negative Regulation Of Cell Proliferation Peptidyl-tyrosine Phosphorylation Megakaryocyte Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Tyrosine Kinase Activity Lamellipodium Morphogenesis	Microtubule Anchoring At Centrosome Centrosome Localization Centrosome-templated Microtubule Nucleation
Pathways		Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS			Cognitive performance ( 20125193)
Protein-Protein Interactions		27 interactors: ABL1 APBB1 CACNA1A CYFIP2 ENAH EPS8 EPS8L1 EVL GAS7 HSPA8 MINK1 NCK1 NCK2 NCKAP1 NEB NIN PAK2 PRPF40A SOS1 SOS2 SPTA1 SPTAN1 SRRM1 TCERG1 VASP WASF1 WASF2	9 interactors: ABI1 AURKA BICD1 C14orf166 GSK3B PIAS1 PRKACA SUMO1 UBE2I
Entrez ID		10006	51199
HPRD ID		04336	09785
Ensembl ID		ENSG00000136754	ENSG00000100503
Uniprot IDs		B6VEX3 B6VEX4 B6VEX5 Q8IZP0	Q5XUU0 Q8N4C6
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuron Projection Morphogenesis Cell Projection Morphogenesis Cell Part Morphogenesis Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Movement Of Cell Or Subcellular Component Neuron Projection Development Cell Morphogenesis Axon Guidance Cell Morphogenesis Involved In Differentiation Neuron Development Locomotion Actin Filament-based Process Regulation Of Actin Cytoskeleton Organization Axonogenesis Neuron Differentiation Regulation Of Actin Filament-based Process Axon Development Actin Cytoskeleton Organization Chemotaxis Regulation Of Cellular Component Organization Regulation Of Cytoskeleton Organization Cytoskeleton Organization Cell Development Actin Filament Organization Generation Of Neurons Neurogenesis Anatomical Structure Morphogenesis Nervous System Development Regulation Of Actin Filament Length Regulation Of Organelle Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Actin Filament Polymerization Immune Response-regulating Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To External Stimulus Regulation Of Cellular Component Size Regulation Of Actin Polymerization Or Depolymerization System Development Rac Protein Signal Transduction Cell Differentiation Fc Receptor Signaling Pathway Multicellular Organismal Development Organelle Organization Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Actin Polymerization Or Depolymerization Anatomical Structure Development	Regulation Of Proteasomal Protein Catabolic Process Peptidyl-amino Acid Modification Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Protein Sumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Binding Regulation Of Proteolysis Positive Regulation Of Proteolysis Innate Immune Response Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Binding Peptidyl-serine Phosphorylation Positive Regulation Of Protein Export From Nucleus Protein Localization To Cytoskeleton Regulation Of Protein Binding Regulation Of Cellular Protein Metabolic Process Protein Localization To Organelle Cellular Protein Modification Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Immune Response Regulation Of Immune System Process Regulation Of Cardiac Muscle Hypertrophy Regulation Of Protein Export From Nucleus Defense Response Negative Regulation Of Biosynthetic Process Response To Cytokine Histone Phosphorylation Peptidyl-lysine Modification Regulation Of Signal Transduction Cellular Protein Metabolic Process Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cell Differentiation Regulation Of Immune Response Negative Regulation Of Protein Binding Positive Regulation Of Protein Modification Process Nuclear Envelope Organization Regulation Of Signaling Organelle Organization
Tagcloud ?		aba abl1 abscisic advantage arabidopsis assayed character contrary copies defense dormancy drought implicates lap le25 meja mrnas pin2 proteinase requisite seed signalling tas14 tomato transcripts transformants wilty wound wounding	3op amido arbuzov arhnp arnc carbamoyl carboxylation cnar dinickel dismantling ipr ipr2 isonitrile methacrylamide narh nhar nix ococh opr2 osime3 phosphinate pincer poc poch2 reactivities siloxide siloxido trinickel valent
Tagcloud (Difference) ?		aba abl1 abscisic advantage arabidopsis assayed character contrary copies defense dormancy drought implicates lap le25 meja mrnas pin2 proteinase requisite seed signalling tas14 tomato transcripts transformants wilty wound wounding	3op amido arbuzov arhnp arnc carbamoyl carboxylation cnar dinickel dismantling ipr ipr2 isonitrile methacrylamide narh nhar nix ococh opr2 osime3 phosphinate pincer poc poch2 reactivities siloxide siloxido trinickel valent
Tagcloud (Intersection) ?