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MED6 and CTDP1
Number of citations of the paper that reports this interaction (PMID
16239144
)
97
Data Source:
BioGRID
(pull down)
MED6
CTDP1
Gene Name
mediator complex subunit 6
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Membrane
Mediator Complex
Spindle Pole
Nucleoplasm
Cytoplasm
Centrosome
Spindle
Actin Cytoskeleton
Midbody
Spindle Midzone
Molecular Function
RNA Polymerase II Transcription Cofactor Activity
Transcription Coactivator Activity
Protein Binding
Transcription Factor Binding
DNA-directed RNA Polymerase Activity
CTD Phosphatase Activity
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Protein Dephosphorylation
Exit From Mitosis
Gene Expression
Viral Process
Positive Regulation Of Viral Transcription
Cell Division
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
RNA Polymerase II Pre-transcription Events
Late Phase of HIV Life Cycle
Pausing and recovery of Tat-mediated HIV elongation
Formation of RNA Pol II elongation complex
HIV elongation arrest and recovery
HIV Life Cycle
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
HIV Transcription Elongation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Schizophrenia (
23212062
)
Protein-Protein Interactions
15 interactors:
BCL6
CTDP1
ESR1
ESR2
MED25
MED8
MED9
PARP1
RARA
SMAD1
SMAD2
SMARCA4
SREBF1
SUZ12
TARDBP
42 interactors:
CDK7
CDK8
CDK9
CSNK2A1
CSNK2A2
CSNK2B
E2F1
ELP2
ELP3
ERH
GTF2F1
HIST1H4A
HIST2H2AC
INTS1
INTS3
INTS6
INTS7
INTS8
MED1
MED14
MED15
MED16
MED17
MED23
MED24
MED25
MED26
MED4
MED6
MED7
MED8
NDRG2
POLR2A
POLR2B
PRKDC
PRMT5
SNRNP70
SNRPB
STK38
TCEA1
UPP1
WDR77
Entrez ID
10001
9150
HPRD ID
04284
05377
Ensembl ID
ENSG00000133997
ENSG00000060069
Uniprot IDs
O75586
Q9Y5B0
PDB IDs
1J2X
1ONV
2K7L
Enriched GO Terms of Interacting Partners
?
Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Gene Expression
Negative Regulation Of Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
DNA-templated Transcription, Initiation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Intracellular Estrogen Receptor Signaling Pathway
Organ Growth
Regulation Of Binding
Positive Regulation Of Metabolic Process
Positive Regulation Of Binding
Regulation Of Cell Proliferation
Tissue Morphogenesis
Negative Regulation Of Cell Proliferation
Urogenital System Development
Cellular Response To Organic Cyclic Compound
Cellular Metabolic Process
Primary MiRNA Processing
Epithelial Cell Development
Regulation Of Gene Expression, Epigenetic
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Nucleobase-containing Compound Metabolic Process
RNA Metabolic Process
Transcription From RNA Polymerase II Promoter
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Transcription, DNA-templated
Gene Expression
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Transcription Elongation From RNA Polymerase II Promoter
Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Androgen Receptor Signaling Pathway
Regulation Of RNA Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
DNA-templated Transcription, Elongation
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Gene Expression
Regulation Of Metabolic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Viral Transcription
NcRNA Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
SnRNA Processing
Regulation Of Viral Transcription
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Viral Process
Stem Cell Maintenance
SnRNA Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Metabolic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cell Cycle Checkpoint
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Stem Cell Development
Positive Regulation Of Metabolic Process
7-methylguanosine MRNA Capping
Regulation Of Viral Process
Tagcloud
?
13q14
18qtel
1p32
3p14
3q21
4q11
4q24
5p13
5p15
5ptel
8p23
9qtel
c84c11
cgh
d1s427
d5s23
d8s504
d9s325
dab2
dxs7132
faf1
fhit
genosensor
imbalances
q12
rbp1
rbp2
shgc
xq12
Tagcloud (Difference)
?
13q14
18qtel
1p32
3p14
3q21
4q11
4q24
5p13
5p15
5ptel
8p23
9qtel
c84c11
cgh
d1s427
d5s23
d8s504
d9s325
dab2
dxs7132
faf1
fhit
genosensor
imbalances
q12
rbp1
rbp2
shgc
xq12
Tagcloud (Intersection)
?