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MED6
Gene Name
mediator complex subunit 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Membrane
Mediator Complex
Molecular Function
RNA Polymerase II Transcription Cofactor Activity
Transcription Coactivator Activity
Protein Binding
Transcription Factor Binding
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-protein Interactions
15 interactors:
BCL6
CTDP1
ESR1
ESR2
MED25
MED8
MED9
PARP1
RARA
SMAD1
SMAD2
SMARCA4
SREBF1
SUZ12
TARDBP
Entrez ID
10001
HPRD ID
04284
Ensembl ID
ENSG00000133997
Uniprot IDs
O75586
PDB IDs
Enriched GO Terms of Interacting Partners
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Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Gene Expression
Negative Regulation Of Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
DNA-templated Transcription, Initiation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Intracellular Estrogen Receptor Signaling Pathway
Organ Growth
Regulation Of Binding
Positive Regulation Of Metabolic Process
Positive Regulation Of Binding
Regulation Of Cell Proliferation
Tissue Morphogenesis
Negative Regulation Of Cell Proliferation
Urogenital System Development
Cellular Response To Organic Cyclic Compound
Cellular Metabolic Process
Primary MiRNA Processing
Epithelial Cell Development
Regulation Of Gene Expression, Epigenetic
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