RABGAP1L and MAP1LC3A

Number of citations of the paper that reports this interaction (PubMedID 22354992)
55

Data Source:
BioGRID (pull down)

		RABGAP1L	MAP1LC3A
Description		RAB GTPase activating protein 1 like	microtubule associated protein 1 light chain 3 alpha
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Early Endosome Golgi Apparatus Cytoplasmic Vesicle	Autophagosome Membrane Cytoplasm Late Endosome Autophagosome Cytosol Cytoskeleton Microtubule Endomembrane System Membrane Organelle Membrane Cytoplasmic Vesicle Autolysosome Synapse Glutamatergic Synapse
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding
	Biological Process	Endocytosis Protein Transport Regulation Of Protein Localization	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation JNK Cascade Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Response To Nutrient Levels Cellular Response To Amino Acid Starvation P38MAPK Cascade SMAD Protein Signal Transduction Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Cellular Response To Oxygen-glucose Deprivation Autophagosome Maturation
Pathways			Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Adult body size ( 32376654) Caffeine consumption from coffee or tea ( 33287642) Caffeine consumption from tea ( 33287642) Cerebrospinal fluid t-tau:AB1-42 ratio ( 26252872) Chronotype ( 30696823) Daytime nap ( 33568662) Femur bone mineral density x serum urate levels interaction ( 34046847) Medication use (anilides) ( 31015401) Neutrophil count ( 32888494) Systemic lupus erythematosus ( 26606652 33536424) Tea consumption ( 31046077) White blood cell count ( 32888494)	Alanine aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		12 interacting genes: ACAP1 ARFGAP1 DBN1 GABARAPL1 MAP1LC3A RAB13 RAB34 RAB36 RB1 TSPAN2 UQCC2 WDFY3	100 interacting genes: ABTB3 AKAP13 AMBRA1 ANK2 ANK3 ANKRD62 AP5B1 APOBR APP APPL1 ARHGAP6 ATF7IP2 ATG13 ATG2A ATG4B ATG7 ATXN3 BCL9 BNIP3L BRD9 CAMSAP1 CARS2 CCPG1 CDC37 CSAG1 DPPA4 DVL2 EPHA7 FUNDC1 GPSM1 HTATSF1 IRGQ IRS4 KIF15 KXD1 LINC00696 LMNB1 MAP1A MAP1S MAVS MDM2 MEFV MREG MRTFA MTX1 MYBPC1 NBR1 NCOR1 NEDD4 NEDD4L NEK9 NEURL4 OPRM1 OPTN PCNT PHB1 PIAS4 PRPF40A RABGAP1 RABGAP1L RASAL3 RDH12 RELB RESF1 RETREG3 RIC1 RTKN RTN3 SEC62 SLA2 SP1 SP3 SRPK1 STBD1 STK10 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TMEM132C TNIP1 TP53INP1 TP53INP2 TRIM21 TRIM25 TRIM32 TTN TUBA4A VPS9D1 ZBTB48 ZKSCAN4 ZNF304
Entrez ID		9910	84557
HPRD ID		16464	03144
Ensembl ID		ENSG00000152061	ENSG00000101460
Uniprot IDs		A0A0U1RRM5 A0A804HKD7 B7ZAP0 F1LJ00 F5H8L0 Q5R372 Q9UEL5 Q9Y3L8	Q9H492
PDB IDs		3HZJ	3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR 6TBE 7R9W 7R9Z 7RA0 8T2L 8T35 8T36 8T4T
Enriched GO Terms of Interacting Partners?		Autophagosome Autophagosome Membrane Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Macroautophagy Intracellular Protein Localization Protein Transport Trans-Golgi Network To Recycling Endosome Transport Mitophagy Autophagosome Maturation Golgi To Plasma Membrane Transport Positive Regulation Of Receptor Localization To Synapse Cell Communication By Chemical Coupling Membrane GTPase Activity Cellular Response To Insulin Stimulus Establishment Of Protein Localization GTP Binding Post-Golgi Vesicle-mediated Transport Plasma Membrane Bounded Cell Projection Organization Cytoplasmic Vesicle Recycling Endosome Membrane Protein Localization To Cell Leading Edge Golgi Apparatus Establishment Of Sertoli Cell Barrier Regulation Of Smoothened Signaling Pathway Ubiquitin Protein Ligase Binding Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Lipid Kinase Activity PML Body Chromatin Lock Complex Positive Regulation Of Collagen Fibril Organization Microglia Development Autophagy Autophagosome Organization Autophagy Of Mitochondrion Autophagosome Assembly Cellular Response To Oxygen-glucose Deprivation Phospholipid Binding	Autophagosome GTPase Activator Activity Regulation Of Cilium Assembly Autophagy Macroautophagy Positive Regulation Of Catabolic Process Positive Regulation Of Autophagy Regulation Of Organelle Assembly Autophagosome Assembly Regulation Of Cell Projection Organization Autophagosome Organization Regulation Of Cell Projection Assembly Cytoplasmic Vesicle Regulation Of Autophagy Regulation Of Plasma Membrane Bounded Cell Projection Organization Autophagy Of Mitochondrion Organelle Organization Cytosol Vacuole Organization Mitophagy Positive Regulation Of Macroautophagy Regulation Of Macroautophagy Regulation Of Cellular Component Organization Piecemeal Microautophagy Of The Nucleus Regulation Of Organelle Organization Microautophagy Nucleophagy Positive Regulation Of Metabolic Process Substrate Localization To Autophagosome M Band Cytoskeleton Organization Phagophore Assembly Site Vesicle-mediated Transport Transcription Repressor Complex Intracellular Protein Localization Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Microtubule Associated Complex Regulation Of Protein Localization Negative Regulation Of Viral Process Catabolic Process Protein Kinase Regulator Activity Suppression Of Viral Release By Host Regulation Of Viral Process Regulation Of GTPase Activity Cytoplasm Ubiquitin Protein Ligase Activity Positive Regulation Of Protein Catabolic Process Cytoskeletal Anchor Activity Protein-macromolecule Adaptor Activity
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