RABGAP1L and ACAP1

Number of citations of the paper that reports this interaction (PubMedID 25814554)
62

Data Source:
BioGRID (two hybrid)

		RABGAP1L	ACAP1
Description		RAB GTPase activating protein 1 like	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Early Endosome Golgi Apparatus Cytoplasmic Vesicle	Cytoplasm Endosome Membrane Recycling Endosome Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Endocytosis Protein Transport Regulation Of Protein Localization	Protein Transport
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Caffeine consumption from coffee or tea ( 33287642) Caffeine consumption from tea ( 33287642) Cerebrospinal fluid t-tau:AB1-42 ratio ( 26252872) Chronotype ( 30696823) Daytime nap ( 33568662) Femur bone mineral density x serum urate levels interaction ( 34046847) Medication use (anilides) ( 31015401) Neutrophil count ( 32888494) Systemic lupus erythematosus ( 26606652 33536424) Tea consumption ( 31046077) White blood cell count ( 32888494)	Autoimmune thyroid disease ( 32581359) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Systemic lupus erythematosus ( 33272962 33536424) White blood cell count ( 32888494)
Interacting Genes		12 interacting genes: ACAP1 ARFGAP1 DBN1 GABARAPL1 MAP1LC3A RAB13 RAB34 RAB36 RB1 TSPAN2 UQCC2 WDFY3	12 interacting genes: AKT1 FCHSD2 GRB2 IFFO1 ITGB1 NEBL RABGAP1L SH3RF1 SNCA TFRC UQCRB VAMP3
Entrez ID		9910	9744
HPRD ID		16464	08474
Ensembl ID		ENSG00000152061	ENSG00000072818
Uniprot IDs		A0A0U1RRM5 A0A804HKD7 B7ZAP0 F1LJ00 F5H8L0 Q5R372 Q9UEL5 Q9Y3L8	Q15027
PDB IDs		3HZJ	3JUE 3T9K 4CKG 4CKH 4F1P 4NSW 5H3D
Enriched GO Terms of Interacting Partners?		Autophagosome Autophagosome Membrane Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Macroautophagy Intracellular Protein Localization Protein Transport Trans-Golgi Network To Recycling Endosome Transport Mitophagy Autophagosome Maturation Golgi To Plasma Membrane Transport Positive Regulation Of Receptor Localization To Synapse Cell Communication By Chemical Coupling Membrane GTPase Activity Cellular Response To Insulin Stimulus Establishment Of Protein Localization GTP Binding Post-Golgi Vesicle-mediated Transport Plasma Membrane Bounded Cell Projection Organization Cytoplasmic Vesicle Recycling Endosome Membrane Protein Localization To Cell Leading Edge Golgi Apparatus Establishment Of Sertoli Cell Barrier Regulation Of Smoothened Signaling Pathway Ubiquitin Protein Ligase Binding Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Lipid Kinase Activity PML Body Chromatin Lock Complex Positive Regulation Of Collagen Fibril Organization Microglia Development Autophagy Autophagosome Organization Autophagy Of Mitochondrion Autophagosome Assembly Cellular Response To Oxygen-glucose Deprivation Phospholipid Binding	Vesicle-mediated Transport Receptor Internalization Receptor-mediated Endocytosis Endocytosis Import Into Cell Recycling Endosome Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Protein Localization To Cell Periphery SNARE Complex Assembly Positive Regulation Of Receptor Recycling Regulation Of Cell Activation Positive Regulation Of Fibroblast Migration Perinuclear Region Of Cytoplasm Regulation Of Neurotransmitter Uptake Endosome Regulation Of T Cell Activation Regulation Of Receptor Recycling Phosphatidylinositol-3,4-bisphosphate Binding Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Regulation Of Protein Localization To Cell Periphery Cell Cortex Protein Kinase Binding Cellular Response To Low-density Lipoprotein Particle Stimulus Cell Migration Involved In Sprouting Angiogenesis Regulation Of Protein Localization Positive Regulation Of Protein Localization Negative Regulation Of Programmed Cell Death Regulation Of Protein-containing Complex Assembly Organelle Localization Response To Iron Ion Response To Copper Ion Lamellipodium Golgi To Plasma Membrane Protein Transport Blood Vessel Endothelial Cell Migration Cellular Response To Lipoprotein Particle Stimulus Phosphatidylinositol-3,4,5-trisphosphate Binding Positive Regulation Of Organelle Organization Regulation Of Lymphocyte Activation Regulation Of Immune System Process Regulation Of Fibroblast Migration Response To Cytokine T Cell Costimulation Response To Peptide Postsynapse Positive Regulation Of Actin Filament Polymerization Hsp70 Protein Binding Protein Transport Positive Regulation Of Cellular Component Organization
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