CCNB1IP1 and KRT15

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CCNB1IP1	KRT15
Description		cyclin B1 interacting protein 1	keratin 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Synaptonemal Complex Nucleus Chromosome	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis Scaffold Protein Binding
	Biological Process	Blastocyst Formation Reciprocal Meiotic Recombination Spermatid Development Protein Ubiquitination Chiasma Assembly Meiotic Cell Cycle	Morphogenesis Of An Epithelium Epidermis Development Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS
Interacting Genes		12 interacting genes: APP CCNB1 CDK1 CUL5 EPM2AIP1 KEAP1 KRT15 NF2 NTAQ1 PRKAA2 SYT17 UBE2L3	144 interacting genes: ABI2 ABI3 ABLIM1 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5PO BEX2 C1orf216 CALCOCO1 CARD9 CATSPERT CCDC120 CCDC185 CCDC187 CCDC87 CCHCR1 CCNB1IP1 CCNC CDK18 CEP57 COX5B CREB5 CYTH4 DEPP1 DES DEUP1 DGCR6L DRC4 DTNB EFHC1 ENKD1 EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAPLN2 HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KDM1A KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT1 KRT18 KRT19 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RAMAC RCOR3 RHPN1 RIBC1 RIBC2 RNF6 RPP25 RSPH14 SGF29 SIRPA SMARCB1 SMARCD1 SMARCE1 SNAPIN SPG21 SSX2IP TBC1D21 TCHP TEKT4 TELO2 TIMM8A TLE5 TMSB4X TRIM42 TRIML2 TSG101 TTC23 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638 ZNF688
Entrez ID		57820	3866
HPRD ID		07000	01009
Ensembl ID		ENSG00000100814	ENSG00000171346
Uniprot IDs		A0A384MR52 Q9NPC3	B3KVF5 P19012
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Generation Of Precursor Metabolites And Energy Cyclin B1-CDK1 Complex Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Cell Cycle Phase Transition Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Ventricular Cardiac Muscle Cell Development Protein Polyubiquitination Regulation Of Developmental Growth Response To Metal Ion Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Small Molecule Metabolic Process Regulation Of Protein Localization To Nucleus Positive Regulation Of Glycolytic Process Nucleus Positive Regulation Of Protein Localization Mitotic Cell Cycle Phase Transition Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Developmental Growth Positive Regulation Of Cardiac Muscle Cell Proliferation Post-translational Protein Modification Positive Regulation Of Chromosome Segregation Cellular Response To Metal Ion Positive Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Protein Localization Response To Copper Ion Positive Regulation Of ATP Metabolic Process Positive Regulation Of Heart Growth Cytosol Negative Regulation Of Cell-matrix Adhesion Cardiac Muscle Cell Development Protein K11-linked Ubiquitination Cellular Response To Oxidative Stress Regulation Of Cardiac Muscle Cell Proliferation Protein Modification Process Cardiac Cell Development Regulation Of Developmental Process Positive Regulation Of Cellular Component Organization Amyloid-beta Complex Regulation Of Cellular Component Organization Growth Cone Lamellipodium Regulation Of Growth Regulation Of Response To Calcium Ion Regulation Of Glycolytic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Organ Growth Response To DDT Cell Cycle G2/M Phase Transition	Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Protein Binding Cytoskeleton Structural Constituent Of Cytoskeleton Microtubule-based Process Intermediate Filament Cytoskeleton Microtubule-based Movement Centrosome Axonemal A Tubule Inner Sheath Flagellated Sperm Motility Sperm Motility Intermediate Filament Polymerization Or Depolymerization Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Brahma Complex NpBAF Complex Establishment Of Cell Polarity Involved In Ameboidal Cell Migration RSC-type Complex Regulation Of Sister Chromatid Segregation NBAF Complex Cell Projection Microtubule Cytoskeleton Organization Motile Cilium Nucleosome Disassembly Microtubule Cilium Movement Sperm Mitochondrial Sheath Assembly Protein-DNA Complex Disassembly
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