EIF4A3 and CDCA7L

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EIF4A3	CDCA7L
Gene Name		eukaryotic translation initiation factor 4A3	cell division cycle associated 7-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome	Nucleus Nucleolus Cytoplasm
	Molecular Function	MRNA Binding ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Poly(A) Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Splicing, Via Spliceosome RRNA Processing Gene Expression Negative Regulation Of Translation Cytokine-mediated Signaling Pathway Positive Regulation Of Translation Embryonic Cranial Skeleton Morphogenesis MRNA Transport	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Deadenylation of mRNA ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS			Height ( 20189936)
Protein-Protein Interactions		9 interactors: CASC3 CCDC174 CDCA7L MAGOH NXF1 PDCD4 RBM8A UPF1 YWHAQ	35 interactors: ABT1 ANKRD11 BEND7 BYSL CARD9 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 EIF4A3 FAM9B ING5 KRTAP10-7 LMO1 MDFI MFAP1 MORN3 MYC NOP2 PPP1R16B PRDM14 PRPF31 SSX2IP STX11 SUV39H1 TADA2A TFPT TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZNF250 ZNF821
Entrez ID		9775	55536
HPRD ID		06482	11481
Ensembl ID		ENSG00000141543	ENSG00000164649
Uniprot IDs		P38919	A8K8X5 Q96GN5
PDB IDs		2HXY 2HYI 2J0Q 2J0S 2J0U 2XB2 3EX7
Enriched GO Terms of Interacting Partners?		MRNA Transport RNA Transport RNA Localization MRNA Export From Nucleus RNA Export From Nucleus Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear Export Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Nucleocytoplasmic Transport Nuclear Transport Regulation Of Translation Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression MRNA Metabolic Process Cellular Localization Regulation Of Alternative MRNA Splicing, Via Spliceosome Cytoplasmic Transport Intracellular Transport Termination Of RNA Polymerase II Transcription Cellular Macromolecule Catabolic Process Regulation Of Gene Expression RNA Splicing Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Gene Expression Regulation Of MRNA Splicing, Via Spliceosome DNA-templated Transcription, Termination MRNA Processing Regulation Of Protein Metabolic Process MRNA 3'-end Processing Regulation Of MRNA Processing Regulation Of RNA Splicing RNA 3'-end Processing RNA Processing Transport RNA Metabolic Process Catabolic Process Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Histone MRNA Catabolic Process Poly(A)+ MRNA Export From Nucleus Intracellular MRNA Localization Dosage Compensation By Inactivation Of X Chromosome Regulation Of Translational Termination Negative Regulation Of JUN Kinase Activity Dosage Compensation Histone MRNA Metabolic Process	RNA Metabolic Process RRNA Metabolic Process Nucleobase-containing Compound Metabolic Process RRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Ribonucleoprotein Complex Biogenesis Ribosome Biogenesis Nitrogen Compound Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Transcription, DNA-templated Chromatin Modification Positive Regulation Of Cell Death RNA Biosynthetic Process Chromatin Organization NcRNA Metabolic Process Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromosome Organization Regulation Of RNA Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process Positive Regulation Of JNK Cascade Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Negative Regulation Of Cellular Metabolic Process Macromolecule Biosynthetic Process Organelle Organization Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Maturation Of SSU-rRNA Activation Of JUN Kinase Activity Regulation Of JNK Cascade Blastocyst Formation Histone Modification Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Ribosomal Small Subunit Biogenesis Regulation Of Metabolic Process
Tagcloud ?		attained chmp4c conceptually dba deg degs domestication dudeg dudegs ehh foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592	able accelerate activate collectively colony constitute conversely division ectopic erk1 hcc hepatocellular inhibits interact knockdown malignant mechanistic myc nude overexpression phenotypes promotes promoting regulate strongly subcutaneous transplantation unclear upregulated
Tagcloud (Difference) ?		attained chmp4c conceptually dba deg degs domestication dudeg dudegs ehh foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592	able accelerate activate collectively colony constitute conversely division ectopic erk1 hcc hepatocellular inhibits interact knockdown malignant mechanistic myc nude overexpression phenotypes promotes promoting regulate strongly subcutaneous transplantation unclear upregulated
Tagcloud (Intersection) ?