EIF4A3 and MAGOH

Number of citations of the paper that reports this interaction (PMID 14730019)
44

Data Source:
HPRD (in vivo)

		EIF4A3	MAGOH
Gene Name		eukaryotic translation initiation factor 4A3	mago-nashi homolog, proliferation-associated (Drosophila)
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytosol Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	MRNA Binding ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Poly(A) Binding Poly(A) RNA Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Splicing, Via Spliceosome RRNA Processing Gene Expression Negative Regulation Of Translation Cytokine-mediated Signaling Pathway Positive Regulation Of Translation Embryonic Cranial Skeleton Morphogenesis MRNA Transport	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus Regulation Of Translation RNA Splicing Gene Expression MRNA 3'-end Processing
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Deadenylation of mRNA ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes Deadenylation-dependent mRNA decay	Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CASC3 CCDC174 CDCA7L MAGOH NXF1 PDCD4 RBM8A UPF1 YWHAQ	11 interactors: ALYREF CORO1A EIF4A3 GOLGA2 IPO13 MAP1B NXF1 RBM8A TADA2A XIST YWHAQ
Entrez ID		9775	4116
HPRD ID		06482	04005
Ensembl ID		ENSG00000141543	ENSG00000162385
Uniprot IDs		P38919	B1ARP8 P61326
PDB IDs		2HXY 2HYI 2J0Q 2J0S 2J0U 2XB2 3EX7	1P27 2HYI 2J0Q 2J0S 2XB2 3EX7
Enriched GO Terms of Interacting Partners?		MRNA Transport RNA Transport RNA Localization MRNA Export From Nucleus RNA Export From Nucleus Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear Export Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Nucleocytoplasmic Transport Nuclear Transport Regulation Of Translation Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression MRNA Metabolic Process Cellular Localization Regulation Of Alternative MRNA Splicing, Via Spliceosome Cytoplasmic Transport Intracellular Transport Termination Of RNA Polymerase II Transcription Cellular Macromolecule Catabolic Process Regulation Of Gene Expression RNA Splicing Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Gene Expression Regulation Of MRNA Splicing, Via Spliceosome DNA-templated Transcription, Termination MRNA Processing Regulation Of Protein Metabolic Process MRNA 3'-end Processing Regulation Of MRNA Processing Regulation Of RNA Splicing RNA 3'-end Processing RNA Processing Transport RNA Metabolic Process Catabolic Process Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Histone MRNA Catabolic Process Poly(A)+ MRNA Export From Nucleus Intracellular MRNA Localization Dosage Compensation By Inactivation Of X Chromosome Regulation Of Translational Termination Negative Regulation Of JUN Kinase Activity Dosage Compensation Histone MRNA Metabolic Process	MRNA Transport RNA Transport RNA Localization Intracellular Transport MRNA Export From Nucleus Nucleocytoplasmic Transport Establishment Of Localization In Cell RNA Export From Nucleus Nuclear Transport MRNA 3'-end Processing Cytoplasmic Transport Cellular Localization RNA 3'-end Processing Nuclear Export MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Transport Termination Of RNA Polymerase II Transcription RNA Splicing DNA-templated Transcription, Termination MRNA Processing Regulation Of Intracellular Transport Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Posttranscriptional Regulation Of Gene Expression Early Endosome To Recycling Endosome Transport MRNA Metabolic Process Uropod Organization RNA Processing Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Regulation Of Tubulin Deacetylation Negative Regulation Of Vesicle Fusion RNA Catabolic Process Viral MRNA Export From Host Cell Nucleus Establishment Of Monopolar Cell Polarity Phagolysosome Assembly Poly(A)+ MRNA Export From Nucleus Nerve Growth Factor Signaling Pathway Transcription From RNA Polymerase II Promoter Mitochondrion Transport Along Microtubule Regulation Of Organelle Organization Regulation Of Translation Regulation Of Cellular Component Organization Negative Regulation Of Actin Nucleation Establishment Of Mitochondrion Localization Replication Fork Processing
Tagcloud ?		attained chmp4c conceptually dba deg degs domestication dudeg dudegs ehh foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592	appearance bodies casc3 core correlate correlates cytoplasm cytoplasmic deregulation determining disassembly eif4aiii ejc exon fate foci granules junction loaded localizes mln51 movements onto overexpressed overexpressing rbm8a spliced unlike y14
Tagcloud (Difference) ?		attained chmp4c conceptually dba deg degs domestication dudeg dudegs ehh foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592	appearance bodies casc3 core correlate correlates cytoplasm cytoplasmic deregulation determining disassembly eif4aiii ejc exon fate foci granules junction loaded localizes mln51 movements onto overexpressed overexpressing rbm8a spliced unlike y14
Tagcloud (Intersection) ?