CDCA7L and DEDD2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CDCA7L	DEDD2
Gene Name		cell division cycle associated 7-like	death effector domain containing 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Nucleoplasm Nucleolus
	Molecular Function	Protein Binding	DNA Binding Protein Binding Receptor Signaling Complex Scaffold Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation	Transcription, DNA-templated RNA Processing Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors RRNA Catabolic Process Cellular Homeostasis Apoptotic Nuclear Changes Intracellular Signal Transduction Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Height ( 20189936)
Protein-Protein Interactions		35 interactors: ABT1 ANKRD11 BEND7 BYSL CARD9 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 EIF4A3 FAM9B ING5 KRTAP10-7 LMO1 MDFI MFAP1 MORN3 MYC NOP2 PPP1R16B PRDM14 PRPF31 SSX2IP STX11 SUV39H1 TADA2A TFPT TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZNF250 ZNF821	11 interactors: CASP10 CASP8 CDCA7L CDK6 CFLAR DEDD GTF3C3 HNRNPAB NR2E3 RBFOX2 RHOXF2
Entrez ID		55536	162989
HPRD ID		11481	10868
Ensembl ID		ENSG00000164649	ENSG00000160570
Uniprot IDs		A8K8X5 Q96GN5	Q8WXF8
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process RRNA Metabolic Process Nucleobase-containing Compound Metabolic Process RRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Ribonucleoprotein Complex Biogenesis Ribosome Biogenesis Nitrogen Compound Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Transcription, DNA-templated Chromatin Modification Positive Regulation Of Cell Death RNA Biosynthetic Process Chromatin Organization NcRNA Metabolic Process Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromosome Organization Regulation Of RNA Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process Positive Regulation Of JNK Cascade Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Negative Regulation Of Cellular Metabolic Process Macromolecule Biosynthetic Process Organelle Organization Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Maturation Of SSU-rRNA Activation Of JUN Kinase Activity Regulation Of JNK Cascade Blastocyst Formation Histone Modification Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Ribosomal Small Subunit Biogenesis Regulation Of Metabolic Process	Regulation Of Necroptotic Process Regulation Of Necrotic Cell Death Tissue Development Regulation Of Myeloid Cell Differentiation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intracellular Receptor Signaling Pathway Organ Development Regulation Of Erythrocyte Differentiation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Gene Expression Regulation Of Cell Proliferation Apoptotic Signaling Pathway Cell Dedifferentiation Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Development Programmed Cell Death Activation Of Cysteine-type Endopeptidase Activity System Development Regulation Of Metabolic Process Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Cell Death Death Extrinsic Apoptotic Signaling Pathway Regulation Of Transcription, DNA-templated Zymogen Activation Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Rhodopsin Gene Expression Negative Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter TRAIL-activated Apoptotic Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Regulation Of Rhodopsin Gene Expression Negative Regulation Of Myoblast Fusion Multicellular Organismal Development Positive Regulation Of Peptidase Activity Cell Differentiation Negative Regulation Of Gene Expression Radial Glia Guided Migration Of Purkinje Cell Regulation Of Definitive Erythrocyte Differentiation Anatomical Structure Development Negative Regulation Of Biosynthetic Process
Tagcloud ?		able accelerate activate collectively colony constitute conversely division ectopic erk1 hcc hepatocellular inhibits interact knockdown malignant mechanistic myc nude overexpression phenotypes promotes promoting regulate strongly subcutaneous transplantation unclear upregulated	annotation atra bindings birc3 braf casp4 casp8 changed effector erk expressions fas fate fenretinide fewer hspa1a huh7 inducing mek participated profiled raf ras rxralpha sosc2 tnfaip3 tnfalpha traf2 uses
Tagcloud (Difference) ?		able accelerate activate collectively colony constitute conversely division ectopic erk1 hcc hepatocellular inhibits interact knockdown malignant mechanistic myc nude overexpression phenotypes promotes promoting regulate strongly subcutaneous transplantation unclear upregulated	annotation atra bindings birc3 braf casp4 casp8 changed effector erk expressions fas fate fenretinide fewer hspa1a huh7 inducing mek participated profiled raf ras rxralpha sosc2 tnfaip3 tnfalpha traf2 uses
Tagcloud (Intersection) ?