CDCA7L and NOP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CDCA7L	NOP2
Description		cell division cycle associated 7 like	NOP2 nucleolar protein
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Protein Binding	RNA Binding Protein Binding Methyltransferase Activity RNA Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity RRNA (cytosine-C5-)-methyltransferase Activity Transferase Activity
	Biological Process	Regulation Of DNA-templated Transcription Positive Regulation Of Cell Population Proliferation	Ribosomal Large Subunit Assembly Maturation Of LSU-rRNA RNA Methylation RRNA Processing RNA Processing Positive Regulation Of Cell Population Proliferation Methylation Ribosome Biogenesis Ribosomal Large Subunit Biogenesis RRNA Base Methylation Regulation Of Signal Transduction By P53 Class Mediator
Pathways			rRNA modification in the nucleus and cytosol TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
Drugs
Diseases
GWAS		Breast cancer ( 29059683) Gamma glutamyl transferase levels ( 33339817) Height ( 20189936) Multiple myeloma ( 26007630 33875642) Multiple myeloma and monoclonal gammopathy ( 26007630) Pre-treatment viral load in HIV-1 infection ( 31219150) Squamous cell lung carcinoma ( 28604730) Urate levels in obese individuals ( 25811787)
Interacting Genes		68 interacting genes: ABT1 ANKRD1 ANKRD11 ANKRD23 AVPI1 AXIN1 BAG5 BEND7 BRPF1 BYSL CARD9 CAVIN1 CCDC116 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 DMAP1 EIF4A3 FAM217B FAM9B GOLGA2 GPRASP3 HSF2BP ING5 JADE2 KRTAP10-7 LMO1 MCRS1 MDFI MEOX2 MFAP1 MLH1 MORN3 MRPL28 MYC NDUFB7 NOL12 NOP2 PBX1 PBX2 PICK1 PIH1D1 PIP4K2B PPP1R16A PPP1R16B PRDM14 PRPF31 RRP7A SNRNP48 SSX1 SSX2IP STX11 SUV39H1 TADA2A TFPT TNNI1 TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZGPAT ZNF250 ZNF438 ZNF620 ZNF821	16 interacting genes: CDC42 CDCA7L CEBPA CEP70 KPNA6 MCRS1 MT1F NPM1 PTPRJ PVT1 RAB2B RNF10 SUMO2 UBE2I USP7 VPS52
Entrez ID		55536	4839
HPRD ID		11481	01244
Ensembl ID		ENSG00000164649	ENSG00000111641
Uniprot IDs		A8K8X5 Q96GN5	P46087
PDB IDs		5YI9 6EMO	8FKT 8FKU 8FKV 8FKW 8FKX 8FKY
Enriched GO Terms of Interacting Partners?		Nucleus RRNA Metabolic Process Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding RRNA Processing Regulation Of RNA Metabolic Process Histone Acetyltransferase Complex Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Organization RNA Metabolic Process Chromatin Remodeling Chromosome Nucleolus Nucleic Acid Metabolic Process RNA Processing Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA Metabolic Process Regulation Of Primary Metabolic Process SnoRNA Localization Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Myosin Phosphatase Regulator Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Apoptotic Signaling Pathway MOZ/MORF Histone Acetyltransferase Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Protein Localization To Nucleolus Spliceosomal Complex Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Negative Regulation Of RNA Metabolic Process Skeletal System Morphogenesis DNA Binding Positive Regulation Of Biosynthetic Process Protein-RNA Complex Assembly Titin Binding Regulation Of DNA Replication Dorsal/ventral Axis Specification Regulation Of Signal Transduction By P53 Class Mediator Epigenetic Programming In The Zygotic Pronuclei Positive Regulation Of Telomere Maintenance In Response To DNA Damage	Macrophage Differentiation Positive Regulation Of Protein Localization To Nucleolus Regulation Of Protein Localization To Nucleolus Myeloid Cell Differentiation SUMO Transferase Activity PML Body Leukocyte Differentiation Mononuclear Cell Differentiation Myeloid Leukocyte Differentiation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nuclear Body Presynaptic Cytosol Postsynaptic Cytosol Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of RNA Biosynthetic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Stability Involved In Cellular Response To UV Regulation Of EIF2 Alpha Phosphorylation By DsRNA Embryonic Ectodermal Digestive Tract Development SUMO Conjugating Enzyme Activity Positive Regulation Of Macromolecule Biosynthetic Process Protein Sumoylation Glutamatergic Synapse Postsynapse Regulation Of Vesicle-mediated Transport Nucleolus Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Nuclear Transport Nucleocytoplasmic Transport GBD Domain Binding Storage Vacuole Response To Vitamin B2 C/EBP Complex Regulation Of Endoribonuclease Activity Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Regulation Of Growth Negative Regulation Of Protein Kinase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?