CDCA7L and ANKRD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CDCA7L	ANKRD1
Description		cell division cycle associated 7 like	ankyrin repeat domain 1
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Fibrillar Center Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Myofibril I Band Protein-containing Complex
	Molecular Function	Protein Binding	P53 Binding DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Titin Binding Histone Deacetylase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding R-SMAD Binding
	Biological Process	Regulation Of DNA-templated Transcription Positive Regulation Of Cell Population Proliferation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Skeletal Muscle Cell Differentiation Response To Muscle Stretch Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Sarcomere Organization Positive Regulation Of DNA-templated Transcription Positive Regulation Of Protein Secretion Cardiac Muscle Tissue Morphogenesis Cellular Response To Lipopolysaccharide Cellular Response To Mechanical Stimulus Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Hypoxia Cellular Response To Xenobiotic Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Phospholipase C/protein Kinase C Signal Transduction Negative Regulation Of DNA Biosynthetic Process
Pathways			PPARA activates gene expression
Drugs
Diseases
GWAS		Breast cancer ( 29059683) Gamma glutamyl transferase levels ( 33339817) Height ( 20189936) Multiple myeloma ( 26007630 33875642) Multiple myeloma and monoclonal gammopathy ( 26007630) Pre-treatment viral load in HIV-1 infection ( 31219150) Squamous cell lung carcinoma ( 28604730) Urate levels in obese individuals ( 25811787)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Intraocular pressure ( 29617998) Refractive error ( 32231278)
Interacting Genes		68 interacting genes: ABT1 ANKRD1 ANKRD11 ANKRD23 AVPI1 AXIN1 BAG5 BEND7 BRPF1 BYSL CARD9 CAVIN1 CCDC116 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 DMAP1 EIF4A3 FAM217B FAM9B GOLGA2 GPRASP3 HSF2BP ING5 JADE2 KRTAP10-7 LMO1 MCRS1 MDFI MEOX2 MFAP1 MLH1 MORN3 MRPL28 MYC NDUFB7 NOL12 NOP2 PBX1 PBX2 PICK1 PIH1D1 PIP4K2B PPP1R16A PPP1R16B PRDM14 PRPF31 RRP7A SNRNP48 SSX1 SSX2IP STX11 SUV39H1 TADA2A TFPT TNNI1 TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZGPAT ZNF250 ZNF438 ZNF620 ZNF821	23 interacting genes: APPL1 ARHGDIB ASH2L CASQ2 CDCA7L DNAJB6 DST DYSF LRPPRC MAPRE3 MEOX2 MYBPC1 MYL1 MYOM2 MYPN NAGK REPS1 SPANXN2 TRIM55 TRIM63 TTN TULP3 ZNF446
Entrez ID		55536	27063
HPRD ID		11481	10647
Ensembl ID		ENSG00000164649	ENSG00000148677
Uniprot IDs		A8K8X5 Q96GN5	A0A384NYH5 Q15327
PDB IDs		5YI9 6EMO
Enriched GO Terms of Interacting Partners?		Nucleus RRNA Metabolic Process Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding RRNA Processing Regulation Of RNA Metabolic Process Histone Acetyltransferase Complex Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Organization RNA Metabolic Process Chromatin Remodeling Chromosome Nucleolus Nucleic Acid Metabolic Process RNA Processing Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA Metabolic Process Regulation Of Primary Metabolic Process SnoRNA Localization Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Myosin Phosphatase Regulator Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Apoptotic Signaling Pathway MOZ/MORF Histone Acetyltransferase Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Protein Localization To Nucleolus Spliceosomal Complex Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Negative Regulation Of RNA Metabolic Process Skeletal System Morphogenesis DNA Binding Positive Regulation Of Biosynthetic Process Protein-RNA Complex Assembly Titin Binding Regulation Of DNA Replication Dorsal/ventral Axis Specification Regulation Of Signal Transduction By P53 Class Mediator Epigenetic Programming In The Zygotic Pronuclei Positive Regulation Of Telomere Maintenance In Response To DNA Damage	Z Disc M Band Sarcomere Organization Structural Constituent Of Muscle Muscle Contraction Actin Filament-based Process Actomyosin Structure Organization Muscle System Process Microtubule Actin Cytoskeleton Organization Calcium Ion Binding Titin Binding Contractile Muscle Fiber Muscle Filament Sliding Muscle Alpha-actinin Binding Cytoskeleton Organization Actin-myosin Filament Sliding Microtubule Plus-end Binding Negative Regulation Of Phagocytosis Myosin Filament Microtubule Plus-end I Band Calcium Ion Sequestering Activity Actin-mediated Cell Contraction Monocyte Activation Involved In Immune Response Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis N-acetylglucosamine Kinase Activity Muramyl Dipeptide Kinase Activity Beta-tubulin Binding Cardiac Muscle Contraction Structural Molecule Activity H Zone Purkinje Myocyte To Ventricular Cardiac Muscle Cell Signaling Limb Development Myofibril Sarcomere Titin-telethonin Complex Structural Molecule Activity Conferring Elasticity Condensed Nuclear Chromosome Sarcomerogenesis Bronchus Morphogenesis Negative Regulation Of Mitochondrial MRNA Catabolic Process Negative Regulation Of Mitochondrial RNA Catabolic Process Positive Regulation Of Macropinocytosis N-acylmannosamine Kinase Activity N-acetylmannosamine Metabolic Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
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