TMEM94 and LTB4R2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		TMEM94	LTB4R2
Description		transmembrane protein 94	leukotriene B4 receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Nucleoplasm Plasma Membrane Membrane
	Molecular Function	P-type Magnesium Transporter Activity	Leukotriene B4 Receptor Activity G Protein-coupled Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Monoatomic Ion Transport Intracellular Magnesium Ion Homeostasis Magnesium Ion Transport From Cytosol To Endoplasmic Reticulum	Chemotaxis Signal Transduction G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Keratinocyte Migration Leukotriene Signaling Pathway
Pathways			Leukotriene receptors G alpha (q) signalling events
Drugs			Amelubant Leukotriene B4
Diseases
GWAS			Anorectal malformation ( 31136621) Height ( 28552196)
Interacting Genes		5 interacting genes: BUD31 GPR35 HTR2C LTB4R2 MC4R	46 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MYO1E OBSL1 P4HTM PER1 PIGM PKD1 RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B
Entrez ID		9772	56413
HPRD ID		11068	16153
Ensembl ID		ENSG00000177728	ENSG00000213906
Uniprot IDs		B7Z9U5 J3QLC5 J3QRY7 J3QSG7 Q12767	B4E292 Q9NPC1
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Feeding Behavior Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding Melanocyte-stimulating Hormone Receptor Activity Response To Melanocyte-stimulating Hormone Leukotriene B4 Receptor Activity Leukotriene Receptor Activity G Protein-coupled Serotonin Receptor Complex Regulation Of Corticotropin-releasing Hormone Secretion Leukotriene Signaling Pathway Melanocortin Receptor Activity Keratinocyte Migration C-X-C Chemokine Receptor Activity Negative Regulation Of Voltage-gated Calcium Channel Activity Phospholipase C-activating Serotonin Receptor Signaling Pathway Regulation Of Eating Behavior Serotonin Binding Positive Regulation Of Phospholipid Biosynthetic Process Serotonin Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity G Protein-coupled Serotonin Receptor Activity Serotonin Receptor Activity Positive Regulation Of Bone Resorption Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Phospholipid Biosynthetic Process Neurotransmitter Receptor Activity G Protein-coupled Serotonin Receptor Signaling Pathway Chemokine Receptor Activity Regulation Of Appetite Negative Regulation Of Transporter Activity Neuropeptide Binding Regulation Of Feeding Behavior	Endoplasmic Reticulum Membrane Endoplasmic Reticulum Membrane Extracellular Exosome Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Vesicle Oligosaccharyltransferase Complex B
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