CD151 and ITGA6

Number of citations of the paper that reports this interaction (PMID 10811835)
47

Data Source:
HPRD (in vivo)

		CD151	ITGA6
Gene Name		CD151 molecule (Raph blood group)	integrin, alpha 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane	Basement Membrane Plasma Membrane Cell-cell Adherens Junction Focal Adhesion External Side Of Plasma Membrane Basal Plasma Membrane Cell Surface Hemidesmosome Filopodium Integrin Alpha6-beta4 Complex
	Molecular Function	Integrin Binding Protein Binding	Integrin Binding Protein Binding Laminin Binding Metal Ion Binding
	Biological Process	Cell Adhesion Cell Migration Extracellular Matrix Organization Hemidesmosome Assembly Cell Junction Assembly T Cell Proliferation	Cell-substrate Junction Assembly Cell-matrix Adhesion Integrin-mediated Signaling Pathway Blood Coagulation Ectodermal Cell Differentiation Positive Regulation Of Cell-substrate Adhesion Single Organismal Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Extracellular Matrix Organization Hemidesmosome Assembly Cell-substrate Adhesion Cellular Response To Extracellular Stimulus Cell Adhesion Mediated By Integrin Cell Junction Assembly Nail Development Positive Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Skin Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Filopodium Assembly Digestive Tract Development Brown Fat Cell Differentiation Leukocyte Migration Cellular Response To Organic Cyclic Compound Renal System Development Amelogenesis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Cell junction organization Type I hemidesmosome assembly Collagen formation Assembly of collagen fibrils and other multimeric structures	Cell junction organization Syndecan interactions Type I hemidesmosome assembly Collagen formation Laminin interactions Integrin cell surface interactions Non-integrin membrane-ECM interactions Assembly of collagen fibrils and other multimeric structures Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			Alzheimer's disease biomarkers ( 23419831) Prostate cancer ( 19767753)
Protein-Protein Interactions		7 interactors: GRAMD1C ITGA3 ITGA6 ITGB1 MMP7 PTGFRN RNF128	21 interactors: ADAM9 APP BIN1 CALM1 CANX CD151 CD36 CD63 CD82 COL17A1 GIPC1 GRB2 ITGB1 ITGB4 PCSK5 PLEC PRKCD PXN RABIF RPSA TSPAN4
Entrez ID		977	3655
HPRD ID		03763	00945
Ensembl ID		ENSG00000177697	ENSG00000091409
Uniprot IDs		E9PMR4 P48509 Q6ZNZ0	P23229
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Cell-substrate Adhesion Integrin-mediated Signaling Pathway Cell Adhesion Mediated By Integrin Cell-matrix Adhesion Negative Regulation Of Rho Protein Signal Transduction Regulation Of Cell-substrate Adhesion Cell-substrate Adhesion Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Leukocyte Migration Positive Regulation Of Protein Localization To Plasma Membrane Mesodermal Cell Differentiation Response To Gonadotropin Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Cell Adhesion Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Blood Coagulation Hemostasis Maternal Process Involved In Female Pregnancy Response To Drug Mesoderm Formation Mesoderm Morphogenesis Antibacterial Peptide Secretion Antibacterial Peptide Biosynthetic Process Regulation Of Body Fluid Levels Wound Healing Regulation Of Cell Adhesion Formation Of Primary Germ Layer Response To Wounding Negative Regulation Of Cell Projection Organization Mesoderm Development Regulation Of Collagen Catabolic Process Cell Migration Immune System Process Gastrulation Calcium-independent Cell-matrix Adhesion Cell Junction Assembly Cell Motility Cellular Response To Extracellular Stimulus Formation Of Radial Glial Scaffolds Positive Regulation Of Neuron Projection Development Skin Development Female Pregnancy Ectodermal Cell Differentiation Negative Regulation Of Signal Transduction Learning Or Memory Cell-cell Adhesion Mediated By Integrin	Hemidesmosome Assembly Cell-substrate Junction Assembly Cell Activation Cell-matrix Adhesion Cell Junction Assembly Cell Adhesion Platelet Activation Cell-substrate Adhesion Extracellular Matrix Organization Extracellular Structure Organization Blood Coagulation Hemostasis Response To Wounding Cellular Component Assembly Secretion By Cell Regulation Of Body Fluid Levels Platelet Degranulation Response To Growth Factor Wound Healing Secretion Positive Regulation Of Endocytosis Positive Regulation Of Transport Integrin-mediated Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Regulation Of MAPK Cascade Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway ERBB Signaling Pathway Endocytosis Vesicle-mediated Transport Establishment Of Protein Localization Regulation Of Endocytosis Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Amino Acid Metabolic Process Movement Of Cell Or Subcellular Component Establishment Of Localization In Cell Regulation Of Protein Phosphorylation Cell-cell Adhesion Mediated By Integrin Response To Oxidative Stress Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Transport Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Immune System Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway
Tagcloud ?		ca19 captured cd10 cd11b cd11c cd13 cd138 cd166 cd181 cd24 cd25 cd26 cd31 cd49d cd95 clustering concordance crc dr enabling fluorescently galectin hierarchical infiltrating panels relapse signatures til tsp
Tagcloud (Difference) ?		ca19 captured cd10 cd11b cd11c cd13 cd138 cd166 cd181 cd24 cd25 cd26 cd31 cd49d cd95 clustering concordance crc dr enabling fluorescently galectin hierarchical infiltrating panels relapse signatures til tsp
Tagcloud (Intersection) ?