CD151 and TMEM139

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD151	TMEM139
Description		CD151 molecule (Raph blood group)	transmembrane protein 139
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Basement Membrane Cytosol Plasma Membrane Focal Adhesion Cell Surface Membrane	Membrane
	Molecular Function	Integrin Binding Protein Binding	Protein Binding
	Biological Process	Cell Adhesion Cell Migration Positive Regulation Of Cell Migration T Cell Proliferation Wound Healing, Spreading Of Cells Positive Regulation Of Endocytosis
Pathways		Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly
Drugs
Diseases		Nephropathy with pretibial epidermolysis bullosa and deafness
GWAS		Mean platelet volume ( 27863252 32888494) Platelet count ( 32888494)
Interacting Genes		12 interacting genes: ARL13B BCL7A GRAMD1C ITGA3 ITGA6 ITGB1 KLRC1 MMP7 PTGFRN RNF128 TMEM139 TSPAN18	41 interacting genes: ABHD16A AGTRAP APOL2 ATP6V0C BCL2L2 CD151 CDS2 CLN6 CMTM5 CTSA CXCL16 CYB5B FAXDC2 KCNK1 MALL MARCHF5 MIP NAPB NEDD4 NINJ2 NKG7 NSG1 PLPP4 PMP22 SEC22B SFTPC SLC30A8 SLC35A1 SMCO4 SMURF2 TMEM107 TMEM120B TMEM19 TMEM60 TRAF3IP3 UBIAD1 UPK1B VAMP5 YAP1 YIF1A ZFPL1
Entrez ID		977	135932
HPRD ID		03763	08298
Ensembl ID		ENSG00000177697	ENSG00000178826
Uniprot IDs		P48509 Q6ZNZ0	Q8IV31
PDB IDs
Enriched GO Terms of Interacting Partners?		Integrin Alpha6-beta1 Complex Integrin Alpha3-beta1 Complex Integrin Complex Formation Of Radial Glial Scaffolds Cell-matrix Adhesion Integrin-mediated Signaling Pathway Mesodermal Cell Differentiation Laminin Binding Negative Regulation Of Rho Protein Signal Transduction Cell-substrate Adhesion Myoblast Fusion Fibronectin Binding Receptor Complex Syncytium Formation By Plasma Membrane Fusion Cell-cell Fusion Syncytium Formation Positive Regulation Of Cell Migration Positive Regulation Of Locomotion Positive Regulation Of Cell Motility Integrin Alpha6-beta4 Complex Myoblast Fate Specification Integrin Alpha7-beta1 Complex Inhibitory MHC Class Ib Receptor Activity Antibacterial Peptide Secretion Signaling Receptor Activity Cell Surface Negative Regulation Of Small GTPase Mediated Signal Transduction Synaptic Membrane Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Periphery Neuromuscular Junction Positive Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse Integrin Alpha8-beta1 Complex Integrin Alpha1-beta1 Complex Integrin Alpha5-beta1 Complex Integrin Alpha10-beta1 Complex Integrin Alphav-beta1 Complex Integrin Alpha11-beta1 Complex Cardiac Cell Fate Specification Integrin Alpha9-beta1 Complex HLA-E Specific Inhibitory MHC Class Ib Receptor Activity External Side Of Plasma Membrane Positive Regulation Of GTPase Activity Growth Cone Filopodium Regulation Of Rho Protein Signal Transduction Positive Regulation Of Protein Localization To Membrane Integrin Alpha4-beta1 Complex Integrin Alpha2-beta1 Complex Natural Killer Cell Inhibitory Signaling Pathway CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation	Membrane Endoplasmic Reticulum Membrane Golgi Membrane
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