TBKBP1 and KLHL2

Number of citations of the paper that reports this interaction (PubMedID 19481056)
0

Data Source:
BioGRID (two hybrid)

		TBKBP1	KLHL2
Description		TBK1 binding protein 1	kelch like family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Serine/threonine Protein Kinase Complex	Ruffle Cytoplasm Cytosol Cytoskeleton Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex Cell Projection
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Actin Binding Protein Binding Identical Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Immune System Process Innate Immune Response Defense Response To Virus Type I Interferon-mediated Signaling Pathway	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 21743469 23749187) Asthma ( 31619474) Asthma (childhood onset) ( 31036433) Body mass index ( 26426971 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Human herpes virus 7 U14 antibody levels ( 33204752) Mean corpuscular hemoglobin ( 32888494) Multiple sclerosis ( 22190364) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)	Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)
Interacting Genes		6 interacting genes: AGO2 APBA3 CTNND2 IRAK1 KLHL2 TUBB	29 interacting genes: ACTC1 BCAM BYSL CCDC43 CDC37 CIMIP1 CLK2 CWC22 ELOA KLHL12 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TBKBP1 TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114
Entrez ID		9755	11275
HPRD ID		12239	09311
Ensembl ID		ENSG00000198933	ENSG00000109466
Uniprot IDs		A7MCY6	B4DFZ5 E9PEX9 O95198
PDB IDs			2XN4 4CHB
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Pancreatic Juice Secretion Intracellular Chloride Ion Homeostasis
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