TP53BP1 and ATM

  • Number of citations of the paper that reports this interaction (PMID 12447390)
  • 151
  • Data Source:
  • BioGRID (pull down, enzymatic study, enzymatic study)
  • HPRD (in vivo, in vitro)

TP53BP1

ATM

Gene Name tumor protein p53 binding protein 1 ATM serine/threonine kinase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 34 interactors: ARAP1 ATM BLM BRCA1 CCNB1 CDK1 CRB2 DCLRE1A DCLRE1C DYNLL1 E2F1 EP300 GALNTL5 H2AFX HIST1H4A HIST2H4A HIST4H4 IFI16 LIG4 MDC1 MEOX2 NCOA3 NEK1 NFKB1 PAXIP1 PCNT PLK1 RAD18 RELA SPAG9 TFDP1 TP53 USP28 VAC14 76 interactors: AATF ABL1 AP1B1 AP2A2 AP2B1 AP3B2 ATR BCL10 BLM BRCA1 BRCA2 CDC6 CDKN2C CHD4 CHEK1 CHEK2 CREB1 CSNK1D CXXC5 DAXX DCLRE1C DDX1 DYRK2 E2F1 E4F1 EEF1E1 EIF3E EIF4EBP1 EXO1 FANCD2 FOXO3 H2AFX HIF1A KAT5 KAT8 LIG4 MCM2 MDC1 MDM2 MDM4 MRE11A NBN PARP1 PEX5 POLR2A PRKDC PTS RAD17 RAD51 RAD9A RBBP8 RHEB RNF20 RNF40 RPA1 RPA2 SMC1A SOCS1 SPSB1 STK11 TCL1A TELO2 TERF1 TERF2 TIPARP TOP1 TOPBP1 TP53 TP53BP1 TRAF6 TREX1 VPRBP WRN XPA XRCC5 ZEB1
Entrez ID 7158 472
HPRD ID 05569 06347
Ensembl ID ENSG00000067369 ENSG00000149311
Uniprot IDs F8VY86 Q12888 Q13315
PDB IDs 1GZH 1KZY 1XNI 2G3R 2IG0 2LVM 3LGF 3LGL 3LH0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abstract  adenocarcinoma  bonferroni  carcinogenesis  cardia  cc  confirm  correction  ga  gc  gca  genotype  genotypes  ldr  ligation  needed  nucleotide  p21  p73  polymorphisms  remained  remaining  replication  rs1059234  rs3176352  rs560191  rs762623  snps  tt 
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
Tagcloud (Difference) ?
abstract  adenocarcinoma  bonferroni  carcinogenesis  cardia  cc  confirm  correction  ga  gc  gca  genotype  genotypes  ldr  ligation  needed  nucleotide  p21  p73  polymorphisms  remained  remaining  replication  rs1059234  rs3176352  rs560191  rs762623  snps  tt 
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
Tagcloud (Intersection) ?