FEZ1 and STAR

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FEZ1	STAR
Description		fasciculation and elongation protein zeta 1	steroidogenic acute regulatory protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centrosome Cytoskeleton Microtubule Plasma Membrane Membrane Axon Dendrite Growth Cone Cell Projection Neuronal Cell Body	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix
	Molecular Function	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding	Protein Binding Lipid Binding Cholesterol Binding Cholesterol Transfer Activity
	Biological Process	Mitochondrion Organization Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Hippocampus Development Establishment Of Cell Polarity Establishment Of Mitochondrion Localization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Cellular Response To Growth Factor Stimulus Negative Regulation Of Autophagosome Assembly	Lipid Metabolic Process Steroid Biosynthetic Process Lipid Transport Cholesterol Metabolic Process Glucocorticoid Metabolic Process Intracellular Cholesterol Transport Regulation Of Steroid Biosynthetic Process Positive Regulation Of Bile Acid Biosynthetic Process
Pathways			Pregnenolone biosynthesis Mitochondrial protein degradation
Drugs
Diseases			Congenital adrenal hyperplasia (CAH) 46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS)
GWAS		Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Breast cancer (survival) ( 25890600) Schizophrenia ( 22688191 23894747)	Menopause (age at onset) ( 26414677) Orthostatic hypotension ( 24124408) Schizophrenia ( 29483656)
Interacting Genes		60 interacting genes: BARD1 BORA BRD1 C8orf33 CCL7 CEP126 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 DYRK1A FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT LRIF1 MEST NBR1 NDUFB9 NEK1 NRIP1 OLFML3 P4HB PAM16 PCNT PDCD7 PPP4R3B PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 STAR TAC3 TAF1D TAF9 TBC1D25 TEDC2 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251	12 interacting genes: AGTRAP CCHCR1 CMTM4 DGAT2L6 FEZ1 LIPE MAGEA11 MAPK3 NUCB2 RABEP1 SMPD2 STX8
Entrez ID		9638	6770
HPRD ID		09212	02794
Ensembl ID		ENSG00000149557	ENSG00000147465
Uniprot IDs		Q99689	P49675 Q6IBK0
PDB IDs			3P0L 5OMA 6T5F 6T5H
Enriched GO Terms of Interacting Partners?		Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Autophagosome Microtubule Cytoskeleton Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Response To Stress Centrosome Regulation Of Macroautophagy Microtubule Cytoskeleton Organization Involved In Mitosis Microtubule-based Process Positive Regulation Of Protein Lipidation Cytoskeleton Regulation Of Endoplasmic Reticulum Tubular Network Organization RNA Polymerase II General Transcription Initiation Factor Binding Regulation Of Protein Lipidation Regulation Of Organelle Assembly Regulation Of Microtubule-based Process RNA Polymerase II General Transcription Initiation Factor Activity Positive Regulation Of Macroautophagy Positive Regulation Of Organelle Assembly Regulation Of Autophagy Microtubule Organizing Center Mitotic Spindle Organization Axon Negative Regulation Of Microtubule Polymerization Or Depolymerization Chondroitin Sulfate Binding Regulation Of Autophagosome Assembly Regulation Of Organelle Organization	Caveola
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