FEZ1 and MEST

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		FEZ1	MEST
Gene Name		fasciculation and elongation protein zeta 1 (zygin I)	mesoderm specific transcript
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Microtubule Plasma Membrane Microtubule Cytoskeleton Axon Dendrite	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding	Hydrolase Activity
	Biological Process	Transport Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Establishment Of Mitochondrion Localization Cellular Response To Growth Factor Stimulus	Mesoderm Development Metabolic Process Regulation Of Lipid Storage Response To Retinoic Acid
Pathways
Drugs
Diseases
GWAS		Schizophrenia ( 22688191 23894747)
Protein-Protein Interactions		57 interactors: BARD1 BORA BRD1 C16orf59 C8orf33 CCL7 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT KIAA1377 LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 SMEK2 STAR TAC3 TAF1D TAF9 TBC1D25 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251	16 interactors: APP BAG6 BLOC1S2 CD300C CEP70 CMTM3 CRELD2 DBN1 FEZ1 FST HGS ING5 KIFAP3 MPZL2 ZNF205 ZNF579
Entrez ID		9638	4232
HPRD ID		09212	06776
Ensembl ID		ENSG00000149557	ENSG00000106484
Uniprot IDs		Q99689	A4D1L9 B4DQW6 Q5EB52
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Organelle Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Process Vesicle Transport Along Microtubule Cell Cycle Mitotic Cell Cycle Microtubule-based Process Microtubule Cytoskeleton Organization Regulation Of Metabolic Process Response To Radiation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Heterocycle Metabolic Process Cellular Process Cellular Homeostasis Organelle Transport Along Microtubule Positive Regulation Of Metabolic Process Response To Ionizing Radiation Response To Stimulus Movement Of Cell Or Subcellular Component Cell Division Regulation Of Intracellular Signal Transduction Cell Cycle Process Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Synaptic Transmission Regulation Of Microtubule-based Process Response To Abiotic Stimulus Cellular Nitrogen Compound Metabolic Process Establishment Or Maintenance Of Cell Polarity Cellular Metabolic Process Mitotic Nuclear Division Mitotic Cell Cycle Process Homeostatic Process Regulation Of Signal Transduction Regulation Of Signaling Mitochondrial Calcium Ion Homeostasis Regulation Of Organelle Organization Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Component Organization Nitrogen Compound Metabolic Process DNA-templated Transcription, Elongation Establishment Of Protein Localization To Organelle Anatomical Structure Development Nervous System Development RNA Metabolic Process Diencephalon Development Transcription, DNA-templated	Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Localization Axon Cargo Transport Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Calcium-dependent Cell-cell Adhesion Microtubule-based Movement Regulation Of Gene Expression Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Organelle Localization Regulation Of ERBB Signaling Pathway Synaptic Growth At Neuromuscular Junction Immune System Process Regulation Of Signaling Regulation Of Cell Proliferation Membrane Organization Collateral Sprouting In Absence Of Injury Cell Communication By Chemical Coupling Regulation Of Dendrite Development Organelle Localization Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Cell Differentiation Internal Protein Amino Acid Acetylation Collateral Sprouting Axon Midline Choice Point Recognition Protein Acetylation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Plus-end-directed Vesicle Transport Along Microtubule Regulation Of Cellular Process Axon Choice Point Recognition Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of B Cell Receptor Signaling Pathway Regulation Of Neuron Differentiation Regulation Of Signal Transduction Protein Insertion Into ER Membrane Chemotaxis Establishment Of Localization In Cell Neuron Remodeling Negative Regulation Of Activin Receptor Signaling Pathway Mitochondrial Outer Membrane Permeabilization Platelet Dense Granule Organization Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of Hair Follicle Development Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Establishment Of Vesicle Localization Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365	bovid contributions die diverged domestic establishes evolutionarily father genomes igf2 imprinted imprinting know mammals mother parthenogenetic paternal peg1 placental postimplantation proceed retardation retarded ruminant ruminants sheep theories versa vice
Tagcloud (Difference) ?		atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365	bovid contributions die diverged domestic establishes evolutionarily father genomes igf2 imprinted imprinting know mammals mother parthenogenetic paternal peg1 placental postimplantation proceed retardation retarded ruminant ruminants sheep theories versa vice
Tagcloud (Intersection) ?